scholarly journals Biomedical tissue phantoms with controlled geometric and optical properties for Raman spectroscopy and tomography

The Analyst ◽  
2011 ◽  
Vol 136 (21) ◽  
pp. 4437 ◽  
Author(s):  
Francis W. L. Esmonde-White ◽  
Karen A. Esmonde-White ◽  
Matthew R. Kole ◽  
Steven A. Goldstein ◽  
Blake J. Roessler ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Properties ◽  
Tissue Phantoms

scholarly journals Studying the distribution of deep Raman spectroscopy signals using liquid tissue phantoms with varying optical properties

The Analyst ◽  
2015 ◽  
Vol 140 (15) ◽  
pp. 5112-5119 ◽  
Author(s):  
Martha Z. Vardaki ◽  
Benjamin Gardner ◽  
Nicholas Stone ◽  
Pavel Matousek
Keyword(s):  
Raman Spectroscopy ◽  
Optical Properties ◽  
Tissue Phantoms ◽  
Transmission Raman

We studied experimentally the magnitude and origin of Raman signals in a transmission Raman geometry as a function of optical properties of the medium and the location of Raman scatterer within the phantom.

scholarly journals An experimental and numerical modelling investigation of the optical properties of Intralipid using deep Raman spectroscopy

The Analyst ◽  
2021 ◽  
Author(s):  
Laura Jane Moran ◽  
Freddy Wordingham ◽  
Ben Gardner ◽  
Nick Stone ◽  
Tim J Harries
Keyword(s):  
Raman Spectroscopy ◽  
Monte Carlo ◽  
Optical Properties ◽  
Numerical Modelling ◽  
Monte Carlo Simulations ◽  
Tissue Phantoms

In this study, Monte Carlo simulations were created to investigate the distribution of Raman signals in tissue phantoms and to validate the arctk code that was used. The aim was...

scholarly journals Multi-layered tissue head phantoms for noninvasive optical diagnostics

2015 ◽  
Vol 08 (03) ◽  
pp. 1541005 ◽  
Author(s):  
M. S. Wróbel ◽  
A. P. Popov ◽  
A. V. Bykov ◽  
M. Kinnunen ◽  
M. Jędrzejewska-Szczerska ◽  
...  
Keyword(s):  
Optical Properties ◽  
Near Infrared ◽  
Optical Measurement ◽  
Human Head ◽  
Medical Diagnostics ◽  
Optical Parameters ◽  
Measurement Systems ◽  
Tissue Phantoms ◽  
Optical And Mechanical Properties

Extensive research in the area of optical sensing for medical diagnostics requires development of tissue phantoms with optical properties similar to those of living human tissues. Development and improvement of in vivo optical measurement systems requires the use of stable tissue phantoms with known characteristics, which are mainly used for calibration of such systems and testing their performance over time. Optical and mechanical properties of phantoms depend on their purpose. Nevertheless, they must accurately simulate specific tissues they are supposed to mimic. Many tissues and organs including head possess a multi-layered structure, with specific optical properties of each layer. However, such a structure is not always addressed in the present-day phantoms. In this paper, we focus on the development of a plain-parallel multi-layered phantom with optical properties (reduced scattering coefficient [Formula: see text] and absorption coefficient μa) corresponding to the human head layers, such as skin, skull, and gray and white matter of the brain tissue. The phantom is intended for use in noninvasive diffuse near-infrared spectroscopy (NIRS) of human brain. Optical parameters of the fabricated phantoms are reconstructed using spectrophotometry and inverse adding-doubling calculation method. The results show that polyvinyl chloride-plastisol (PVCP) and zinc oxide ( ZnO ) nanoparticles are suitable materials for fabrication of tissue mimicking phantoms with controlled scattering properties. Good matching was found between optical properties of phantoms and the corresponding values found in the literature.

scholarly journals Discovering new 3D bioprinting applications: Analyzing the case of optical tissue phantoms

2018 ◽  
Vol 5 (1) ◽  
Author(s):  
Marisela Rodriguez-Salvador
Keyword(s):  
Optical Properties ◽  
3D Printing ◽  
Clinical Training ◽  
Three Dimensional ◽  
Biological Tissues ◽  
3D Bioprinting ◽  
Technology Intelligence ◽  
Biomedical Device ◽  
Tissue Phantoms ◽  
Scientific Papers

Optical tissue phantoms enable to mimic the optical properties of biological tissues for biomedical device calibration, new equipment validation, and clinical training for the detection, and treatment of diseases. Unfortunately, current methods for their development present some problems, such as a lack of repeatability in their optical properties. Where the use of three-dimensional (3D) printing or 3D bioprinting could address these issues. This paper aims to evaluate the use of this technology in the development of optical tissue phantoms. A competitive technology intelligence methodology was applied by analyzing Scopus, Web of Science, and patents from January 1, 2000, to July 31, 2018. The main trends regarding methods, materials, and uses, as well as predominant countries, institutions, and journals, were determined. The results revealed that, while 3D printing is already employed (in total, 108 scientific papers and 18 patent families were identified), 3D bioprinting is not yet applied for optical tissue phantoms. Nevertheless, it is expected to have significant growth. This research gives biomedical scientists a new window of opportunity for exploring the use of 3D bioprinting in a new area that may support testing of new equipment and development of techniques for the diagnosis and treatment of diseases.

scholarly journals Laser-generated plasmas by graphene nanoplatelets embedded into polyethylene

2017 ◽  
Vol 35 (2) ◽  
pp. 294-303 ◽  
Author(s):  
L. Torrisi ◽  
G. Ceccio ◽  
N. Restuccia ◽  
E. Messina ◽  
P. G. Gucciardi ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Properties ◽  
Nd:Yag Laser ◽  
Charge Separation ◽  
Ion Beams ◽  
Carbon Ions ◽  
Physical Processes ◽  
Equilibrium Plasma ◽  
Matter Interaction ◽  
Flight Measurements

AbstractGraphene micrometric particles have been embedded into polyethylene at different concentrations by using chemical–physical processes. The synthesized material was characterized in terms of mechanical and optical properties, and Raman spectroscopy. Obtained targets were irradiated by using a Nd:YAG laser at intensities of the order of 1010 W/cm2 to generate non-equilibrium plasma expanding in vacuum. The laser–matter interaction produces charge separation effects with consequent acceleration of protons and carbon ions. Plasma was characterized using time-of-flight measurements of the accelerated ions. Applications of the produced targets in order to generate carbon and proton ion beams from laser-generated plasma are presented and discussed.

Raman Spectroscopy and Optical Properties of Porous Silicon

1993 ◽  
pp. 383-392
Author(s):  
D. J. Lockwood ◽  
G. C. Aers ◽  
L. B. Allard ◽  
B. Bryskiewicz ◽  
S. Charbonneau ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Properties ◽  
Porous Silicon

scholarly journals Preparation, Raman spectroscopy, surface morphology and optical properties of TiPcCl2 nanostructured films: thickness effect

2021 ◽  
Vol 53 (9) ◽  
Author(s):  
S. A. Al-Ghamdi ◽  
Taymour A. Hamdalla ◽  
A. A. A. Darwish ◽  
Ahmed Obaid M. Alzahrani ◽  
E. F. M. El-Zaidia ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Properties ◽  
Surface Morphology ◽  
Thickness Effect ◽  
Nanostructured Films
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