scholarly journals The past, present and future of enzyme measurements using surface enhanced Raman spectroscopy

2010 ◽  
Vol 1 (2) ◽  
pp. 151 ◽  
Author(s):  
Iain A. Larmour ◽  
Karen Faulds ◽  
Duncan Graham
2018 ◽  
Vol 54 (1) ◽  
pp. 10-25 ◽  
Author(s):  
Rajapandiyan Panneerselvam ◽  
Guo-Kun Liu ◽  
Yao-Hui Wang ◽  
Jun-Yang Liu ◽  
Song-Yuan Ding ◽  
...  

This feature article discusses developmental bottleneck issues in surface Raman spectroscopy in its early stages and surface-enhanced Raman spectroscopy (SERS) in the past four decades and future perspectives.


RSC Advances ◽  
2017 ◽  
Vol 7 (25) ◽  
pp. 14959-14965 ◽  
Author(s):  
Xinxin Yu ◽  
Ranran Cai ◽  
Yuqing Song ◽  
Qiang Gao ◽  
Nan Pan ◽  
...  

During the past decades, researchers have made great efforts towards an ideal surface enhanced Raman spectroscopy (SERS) substrate.


2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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