Strategies to prolong the plasma residence time of peptidedrugs

MedChemComm ◽  
2010 ◽  
Vol 1 (5) ◽  
pp. 319-324 ◽  
Author(s):  
Lisa Pollaro ◽  
Christian Heinis
Keyword(s):  
Residence Time ◽  
Peptide Drugs

Well established as well as recently developed strategies to prevent the fast clearance of peptide drugs from the circulation are reviewed.

Residence Time in Hyporheic Bioactive Layers Explains Nitrate Uptake in Streams

2020 ◽  
Author(s):  
Angang Li ◽  
Susana Bernal ◽  
Brady Kohler ◽  
Steven A. Thomas ◽  
Eugènia Martí ◽  
...  
Keyword(s):  
Residence Time ◽  
Nitrate Uptake

Conformationally Constrained Peptide Drugs Targeted at the Blood-Brain Barrier

1995 ◽  
Author(s):  
Thomas P. Davis ◽  
Thomas J. Abbruscato ◽  
Elizabeth Brownson ◽  
Victor J. Hruby
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Peptide Drugs ◽  
Conformationally Constrained ◽  
Blood Brain

Modeling the Effect of Flow Structures on Canal System Residence Time

2008 ◽  
Author(s):  
N. P. Benfer ◽  
B. A. King ◽  
C. J. Lemckert ◽  
S. Zigic
Keyword(s):  
Residence Time ◽  
Flow Structures ◽  
Canal System
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