1-(2-Picolyl)-substituted 1,2,3-triazole as novel chelating ligand for the preparation of ruthenium complexes with potential anticancer activity

2011 ◽  
Vol 40 (19) ◽  
pp. 5188 ◽  
Author(s):  
Ioannis Bratsos ◽  
Damijana Urankar ◽  
Ennio Zangrando ◽  
Petia Genova-Kalou ◽  
Janez Košmrlj ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Ruthenium Complexes ◽  
Chelating Ligand

Fine‐feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity †

2021 ◽  
Author(s):  
Houston D. Cole ◽  
John A. Roque ◽  
Liubov M. Lifshits ◽  
Rachel Hodges ◽  
Patrick C. Barrett ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Ruthenium Complexes

In Vitro Anticancer Activity and Biologically Relevant Metabolization of Organometallic Ruthenium Complexes with Carbohydrate-Based Ligands

2008 ◽  
Vol 14 (29) ◽  
pp. 9046-9057 ◽  
Author(s):  
Isabella Berger ◽  
Muhammad Hanif ◽  
Alexey A. Nazarov ◽  
Christian G. Hartinger ◽  
Roland O. John ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Ruthenium Complexes ◽  
Biologically Relevant

scholarly journals Anticancer activity of multinuclear arene ruthenium complexes coordinated to dendritic polypyridyl scaffolds

2009 ◽  
Vol 694 (21) ◽  
pp. 3470-3476 ◽  
Author(s):  
Preshendren Govender ◽  
Nathan C. Antonels ◽  
Johan Mattsson ◽  
Anna K. Renfrew ◽  
Paul J. Dyson ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Ruthenium Complexes

scholarly journals Anticancer activity of new organo-ruthenium, rhodium and iridium complexes containing the 2-(pyridine-2-yl)thiazole N,N-chelating ligand

2010 ◽  
Vol 695 (8) ◽  
pp. 1119-1125 ◽  
Author(s):  
Michaël Gras ◽  
Bruno Therrien ◽  
Georg Süss-Fink ◽  
Angela Casini ◽  
Fabio Edafe ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Iridium Complexes ◽  
Chelating Ligand

Stabilization for loop isomers of c-myc G-quadruplex DNA and anticancer activity by ruthenium complexes

MedChemComm ◽  
2014 ◽  
Vol 5 (11) ◽  
pp. 1724-1728 ◽  
Author(s):  
Ying Liu ◽  
Yanan Liu ◽  
Licong Yang ◽  
Chengwen Cao ◽  
Yanhui Zhou ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Ruthenium Complexes ◽  
Quadruplex Dna ◽  
G Quadruplex

Thiolato-Bridged Arene-Ruthenium Complexes: Synthesis, Molecular Structure, Reactivity, and Anticancer Activity of the Dinuclear Complexes [(arene)2Ru2(SR)2Cl2]

2011 ◽  
Vol 2012 (9) ◽  
pp. 1531-1535 ◽  
Author(s):  
Anne-Flore Ibao ◽  
Michaël Gras ◽  
Bruno Therrien ◽  
Georg Süss-Fink ◽  
Olivier Zava ◽  
...  
Keyword(s):  
Molecular Structure ◽  
Anticancer Activity ◽  
Ruthenium Complexes ◽  
Dinuclear Complexes

scholarly journals Influence of PPh3 moiety in the anticancer activity of new organometallic ruthenium complexes

2014 ◽  
Vol 136 ◽  
pp. 1-12 ◽  
Author(s):  
Rubén Sáez ◽  
Julia Lorenzo ◽  
Ma Jose Prieto ◽  
Mercè Font-Bardia ◽  
Teresa Calvet ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Ruthenium Complexes

scholarly journals Microwave-Assisted Synthesis of 3,5-Dibenzyl-4-amino-1,2,4-triazole and its Diazo Ligand, Metal Complexes Along with Anticancer Activity

2010 ◽  
Vol 7 (4) ◽  
pp. 1571-1577 ◽  
Author(s):  
Anjali Jha ◽  
Y. L. N. Murthy ◽  
G. Durga ◽  
T. T. Sundari
Keyword(s):  
Microwave Irradiation ◽  
Metal Complexes ◽  
Anticancer Activity ◽  
Cell Lines ◽  
Conventional Method ◽  
Ruthenium Complexes ◽  
Microwave Assisted Synthesis ◽  
Microwave Irradiation Method ◽  
Anticancer Activities ◽  
Microwave Assisted

Synthesis of 3,5-dibenzyl-4-amino-1,2,4-triazole was accomplished via a conventional method as well as microwave irradiation method, followed by diazotization and coupling with 2,4-pentanedione. The dinucleating ligand was isolated and complexed with Ni(II), Cu(II) and Ru(III) chlorides. These complexes were screened on Jurkat, Raji & PBMC cell lines for anticancer activity. Ruthenium complexes showed potential anticancer activities.

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