Magnetic separation and immunoassay of multi-antigen based on surface enhanced Raman spectroscopy

2011 ◽  
Vol 47 (14) ◽  
pp. 4225 ◽  
Author(s):  
Shuai Chen ◽  
Yaxian Yuan ◽  
Jianlin Yao ◽  
Sanyang Han ◽  
Renao Gu
Keyword(s):  
Raman Spectroscopy ◽  
Magnetic Separation ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

scholarly journals Magnetic separation of clenbuterol based on competitive immunoassay and evaluation by surface-enhanced Raman spectroscopy

RSC Advances ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 3388-3397 ◽  
Author(s):  
Chao Wei ◽  
Yi Zong ◽  
Qinghua Guo ◽  
Minmin Xu ◽  
Yaxian Yuan ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Human Health ◽  
Magnetic Separation ◽  
Surface Enhanced Raman Spectroscopy ◽  
Competitive Immunoassay ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

The elimination of β-agonist has attracted considerable interest due to its harmfulness to human health when it existed in pork.

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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