scholarly journals Optimization of dynamic nuclear polarization experiments in aqueous solution at 15 MHz/9.7 GHz: a comparative study with DNP at 140 MHz/94 GHz

2010 ◽  
Vol 12 (22) ◽  
pp. 5893 ◽  
Author(s):  
Maria-Teresa Türke ◽  
Igor Tkach ◽  
Marcel Reese ◽  
Peter Höfer ◽  
Marina Bennati
Keyword(s):  
Aqueous Solution ◽  
Comparative Study ◽  
Dynamic Nuclear Polarization ◽  
Nuclear Polarization

Field Dependent Dynamic Nuclear Polarization with Radicals in Aqueous Solution

2008 ◽  
Vol 130 (11) ◽  
pp. 3254-3255 ◽  
Author(s):  
Peter Höfer ◽  
Giacomo Parigi ◽  
Claudio Luchinat ◽  
Patrick Carl ◽  
Gisela Guthausen ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Dynamic Nuclear Polarization ◽  
Nuclear Polarization ◽  
Field Dependent

1H and13C Dynamic Nuclear Polarization in Aqueous Solution with a Two-Field (0.35 T/14 T) Shuttle DNP Spectrometer

2009 ◽  
Vol 131 (42) ◽  
pp. 15086-15087 ◽  
Author(s):  
Marcel Reese ◽  
Maria-Teresa Türke ◽  
Igor Tkach ◽  
Giacomo Parigi ◽  
Claudio Luchinat ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Dynamic Nuclear Polarization ◽  
Nuclear Polarization

scholarly journals Studies of Dynamic Nuclear Polarization with Nitroxides in Aqueous Solution

2008 ◽  
Vol 34 (3-4) ◽  
pp. 393-398 ◽  
Author(s):  
P. Höfer ◽  
P. Carl ◽  
G. Guthausen ◽  
T. Prisner ◽  
M. Reese ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Dynamic Nuclear Polarization ◽  
Nuclear Polarization

High frequency (140 GHz) dynamic nuclear polarization: Polarization transfer to a solute in frozen aqueous solution

1995 ◽  
Vol 102 (24) ◽  
pp. 9494-9497 ◽  
Author(s):  
G. J. Gerfen ◽  
L. R. Becerra ◽  
D. A. Hall ◽  
R. G. Griffin ◽  
R. J. Temkin ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Dynamic Nuclear Polarization ◽  
High Frequency ◽  
Nuclear Polarization ◽  
Polarization Transfer

scholarly journals Increased flow rate of hyperpolarized aqueous solution for dynamic nuclear polarization-enhanced magnetic resonance imaging achieved by an open Fabry–Pérot type microwave resonator

2020 ◽  
Vol 1 (2) ◽  
pp. 275-284
Author(s):  
Alexey Fedotov ◽  
Ilya Kurakin ◽  
Sebastian Fischer ◽  
Thomas Vogl ◽  
Thomas F. Prisner ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Aqueous Solution ◽  
Magnetic Resonance ◽  
Flow Rate ◽  
Dynamic Nuclear Polarization ◽  
Nuclear Polarization ◽  
Microwave Cavity ◽  
Microwave Resonator ◽  
Resonance Imaging ◽  
Fabry Perot

Abstract. A continuous flow dynamic nuclear polarization (DNP) employing the Overhauser effect at ambient temperatures can be used among other methods to increase sensitivity of magnetic resonance imaging (MRI). The hyperpolarized state of water protons can be achieved by flowing aqueous liquid through a microwave resonator placed directly in the bore of a 1.5 T MRI magnet. Here we describe a new open Fabry–Pérot resonator as DNP polarizer, which exhibits a larger microwave exposure volume for the flowing liquid in comparison with a cylindrical TE013 microwave cavity. The Fabry–Pérot resonator geometry was designed using quasi-optical theory and simulated by CST software. Performance of the new polarizer was tested by MRI DNP experiments on a TEMPOL aqueous solution using a blood-vessel phantom. The Fabry–Pérot resonator revealed a 2-fold larger DNP enhancement with a 4-fold increased flow rate compared to the cylindrical microwave resonator. This increased yield of hyperpolarized liquid allows MRI applications on larger target objects.

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