Role of aromatic amino acid tryptophan UVA-photoproducts in the determination of drug photosensitization mechanism: a comparison between methylene blue and naproxen

2009 ◽  
Vol 8 (10) ◽  
pp. 1467 ◽  
Author(s):  
Alfio Catalfo ◽  
Giuseppina Bracchitta ◽  
Guido De Guidi
Keyword(s):  
Methylene Blue ◽  
Amino Acid ◽  
Aromatic Amino Acid ◽  
Amino Acid Tryptophan

Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding

FEBS Journal ◽  
2005 ◽  
Vol 272 (15) ◽  
pp. 3960-3966 ◽  
Author(s):  
Zhengding Su ◽  
Jiun-Ming Wu ◽  
Huey-Jen Fang ◽  
Tian-Yow Tsong ◽  
Hueih-Min Chen
Keyword(s):  
Amino Acid ◽  
Amino Acid Residue ◽  
Aromatic Amino Acid ◽  
Local Stability ◽  
Staphylococcal Nuclease ◽  
Aromatic Amino Acid Residue

scholarly journals Kynurenine Pathway in Skin Cells: Implications for UV-Induced Skin Damage

2012 ◽  
Vol 5 ◽  
pp. IJTR.S9835 ◽  
Author(s):  
Diba Sheipouri ◽  
Nady Braidy ◽  
Gilles J. Guillemin
Keyword(s):  
Amino Acid ◽  
Essential Amino Acid ◽  
Ultra Violet ◽  
Kynurenine Pathway ◽  
Uv Exposure ◽  
Skin Damage ◽  
Skin Cells ◽  
Amino Acid Tryptophan ◽  
Inflammatory Component

The kynurenine pathway (KP) is the principle route of catabolism of the essential amino acid tryptophan, leading to the production of several neuroactive and immunoregulatory metabolites. Alterations in the KP have been implicated in various neuropsychiatric and neurodegenerative diseases, immunological disorders, and many other diseased states. Although the role of the KP in the skin has been evaluated in small niche fields, limited studies are available regarding the effect of acute ultra violet exposure and the induction of the KP in human skin-derived fibroblasts and keratinocytes. Since UV exposure can illicit an inflammatory component in skin cells, it is highly likely that the KP may be induced in these cells in response to UV exposure. It is also possible that some KP metabolites may act as pro-inflammatory and anti-inflammatory mediators, since the KP is important in immunomodulation.

Determination of the amino acid tryptophan and the biogenic amine tryptamine in foods by the heavy atom induced-room temperature phosphorescence methodology

The Analyst ◽  
2003 ◽  
Vol 128 (4) ◽  
pp. 411-415 ◽  
Author(s):  
Beatriz Cañabate-Díaz ◽  
Antonio Segura Carretero ◽  
Carmen Cruces-Blanco ◽  
Alberto Fernández-Gutiérrez
Keyword(s):  
Amino Acid ◽  
Biogenic Amine ◽  
Room Temperature ◽  
Heavy Atom ◽  
Room Temperature Phosphorescence ◽  
Amino Acid Tryptophan

scholarly journals Fusarochromene, a novel tryptophan-derived metabolite from Fusarium sacchari

2021 ◽  
Vol 19 (1) ◽  
pp. 182-187
Author(s):  
James W. Marshall ◽  
Kate M. J. de Mattos-Shipley ◽  
Iman A. Y. Ghannam ◽  
Asifa Munawar ◽  
Jonathan C. Killen ◽  
...  
Keyword(s):  
Amino Acid ◽  
Aromatic Amino Acid ◽  
Oxidative Cleavage ◽  
Fusarium Sacchari ◽  
Amino Acid Tryptophan

Fusarochromene and the fusarochromanone mycotoxins are derived via oxidative cleavage of the aromatic amino acid tryptophan.

Sign in / Sign up

Export Citation Format

Share Document