Solvent-free Sonogashira coupling reaction via high speed ball milling

2009 ◽  
Vol 11 (11) ◽  
pp. 1821 ◽  
Author(s):  
Dennis A. Fulmer ◽  
William C. Shearouse ◽  
Shareika T. Medonza ◽  
James Mack
Keyword(s):  
Ball Milling ◽  
High Speed ◽  
Coupling Reaction ◽  
Solvent Free ◽  
Sonogashira Coupling ◽  
Sonogashira Coupling Reaction ◽  
High Speed Ball Milling

ChemInform Abstract: Solvent-Free Sonogashira Coupling Reaction via High Speed Ball Milling.

ChemInform ◽  
2010 ◽  
Vol 41 (12) ◽  
Author(s):  
Dennis A. Fulmer ◽  
William C. Shearouse ◽  
Shareika T. Medonza ◽  
James Mack
Keyword(s):  
Ball Milling ◽  
High Speed ◽  
Coupling Reaction ◽  
Solvent Free ◽  
Sonogashira Coupling ◽  
Sonogashira Coupling Reaction ◽  
High Speed Ball Milling

ChemInform Abstract: A Novel Imidazolium-Supported Palladium-Chloroglycine Complex: Copper- and Solvent-Free High-Turnover Catalysts for the Sonogashira Coupling Reaction.

ChemInform ◽  
2013 ◽  
Vol 44 (12) ◽  
pp. no-no
Author(s):  
Parasuraman Karthikeyan ◽  
Prashant Narayan Muskawar ◽  
Sachin Arunrao Aswar ◽  
Pundlik Rambhau Bhagat ◽  
Suresh Kumar Sythana
Keyword(s):  
Coupling Reaction ◽  
Solvent Free ◽  
Sonogashira Coupling ◽  
High Turnover ◽  
Sonogashira Coupling Reaction ◽  
Supported Palladium ◽  
Complex Copper

A Merrifield resin supported Pd–NHC complex with a spacer(Pd–NHC@SP–PS) for the Sonogashira coupling reaction under copper- and solvent-free conditions

2015 ◽  
Vol 39 (3) ◽  
pp. 2333-2341 ◽  
Author(s):  
Sanjay N. Jadhav ◽  
Arjun S. Kumbhar ◽  
Sawanta S. Mali ◽  
Chang Kook Hong ◽  
Rajashri S. Salunkhe
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Solvent Free ◽  
Sonogashira Coupling ◽  
Cross Coupling Reaction ◽  
Solvent Free Conditions ◽  
Sonogashira Coupling Reaction ◽  
Merrifield Resin ◽  
Polymer Supported ◽  
Supported Pd

Synthetic applications of a polymer supported air-stable palladium NHC complex with a spacer (catalyst6, Pd–NHC@SP–PS) and without a spacer (catalyst7, Pd–NHC@PS) have been studied for the Sonogashira cross-coupling reaction.

ChemInform Abstract: Making Kinetic and Thermodynamic Enolates via Solvent-Free High Speed Ball Milling.

ChemInform ◽  
2010 ◽  
Vol 41 (26) ◽  
pp. no-no
Author(s):  
Daniel C. Waddell ◽  
Indre Thiel ◽  
Tammara D. Clark ◽  
S. Tyler Marcum ◽  
James Mack
Keyword(s):  
Ball Milling ◽  
High Speed ◽  
Solvent Free ◽  
High Speed Ball Milling

scholarly journals Cross-Coupling Biarylation of Nitroaryl Chlorides Through High Speed Ball Milling

2015 ◽  
Vol 3 (6) ◽  
pp. 12-35
Author(s):  
Solita Lam ◽  
Yvonne Puplampu Dove ◽  
Adrienne Morris ◽  
Ayunna Epps ◽  
Ghislain R Mandouma
Keyword(s):  
Ball Milling ◽  
High Speed ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Reaction Cross ◽  
Extraction And Purification ◽  
Custom Made ◽  
Ball Milling Technique ◽  
Solvent Free Reaction ◽  
High Speed Ball Milling

Solvent-free reaction using a high-speed ball milling technique has been applied to the classical Ullmann coupling reaction. Cross-coupling biarylation of several nitroaryl chlorides was achieved in good yields when performed in custom-made copper vials through continuous shaking without additional copper or solvent. Cross-coupling products were obtained almost pure and NMR-ready. These reactions were cleaner than solution phase coupling which require longer reaction time in high boiling solvents, and added catalysts as well as lengthy extraction and purification steps. Gram quantities of cross biaryl compounds have been synthesized with larger copper vials, a proof that this method can be used to reduce industrial waste and for sustainability.

Making kinetic and thermodynamic enolates via solvent-free high speed ball milling

2010 ◽  
Vol 12 (2) ◽  
pp. 209-211 ◽  
Author(s):  
Daniel C. Waddell ◽  
Indre Thiel ◽  
Tammara D. Clark ◽  
S. Tyler Marcum ◽  
James Mack
Keyword(s):  
Ball Milling ◽  
High Speed ◽  
Solvent Free ◽  
High Speed Ball Milling
Sign in / Sign up

Export Citation Format

Share Document