scholarly journals The placenta as a barrier for toxic and essential elements in paired maternal and cord blood samples of South African delivering women

2009 ◽  
Vol 11 (7) ◽  
pp. 1322 ◽  
Author(s):  
Cibele V. Rudge ◽  
Halina B. Röllin ◽  
Claudina M. Nogueira ◽  
Yngvar Thomassen ◽  
Marilza C. Rudge ◽  
...  
Keyword(s):  
Cord Blood ◽  
South African ◽  
Essential Elements ◽  
Blood Samples ◽  
Toxic And Essential Elements

scholarly journals The content of toxic and essential elements in trabecular and cortical femoral neck: a correlation with whole blood samples

2019 ◽  
Vol 26 (16) ◽  
pp. 16577-16587 ◽  
Author(s):  
Aleksandar Stojsavljević ◽  
Sandra Škrivanj ◽  
Jelena Trifković ◽  
Nenad Djoković ◽  
Srećko R Trifunović ◽  
...  
Keyword(s):  
Femoral Neck ◽  
Whole Blood ◽  
Essential Elements ◽  
Blood Samples ◽  
Toxic And Essential Elements ◽  
Whole Blood Samples

P581 Evaluation of placental permeability for toxic and essential elements in South African delivering women

2009 ◽  
Vol 107 ◽  
pp. S578-S578
Author(s):  
C. Rudge ◽  
H. Rollin ◽  
C. Nogueira ◽  
Y. Thomassen ◽  
M. Rudge ◽  
...  
Keyword(s):  
South African ◽  
Essential Elements ◽  
Toxic And Essential Elements

Production of dendritic cells and cytokine-induced killer cells from banked umbilical cord blood samples

2015 ◽  
Vol 2 (11) ◽  
Author(s):  
Phuc Van Pham ◽  
Binh Thanh Vu ◽  
Viet Quoc Pham ◽  
Phong Minh Le ◽  
Hanh Thi Le ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Killer Cells ◽  
Blood Samples

Comparison of Maternal Sera, Cord Blood, and Neonatal Sera for Detecting Presumptive Congenital Syphilis: Relationship With Maternal Treatment

PEDIATRICS ◽  
1993 ◽  
Vol 91 (1) ◽  
pp. 88-91
Author(s):  
Rakesh S. Chhabra ◽  
Luc P. Brion ◽  
Martha Castro ◽  
Lawrence Freundlich ◽  
Joy H. Glaser
Keyword(s):  
Cord Blood ◽  
Prenatal Exposure ◽  
Congenital Syphilis ◽  
Multiple Comparisons ◽  
Serologic Test ◽  
Blood Samples ◽  
The Past ◽  
Maternal Treatment ◽  
Treatment Administration

The incidence of congenital syphilis has increased rapidly over the past few years. Most infected mothers and their newborns are asymptomatic at birth and diagnosis depends on serologic testing during pregnancy and at delivery. This study was initiated to compare maternal sera, cord blood, and neonatal sera for detecting presumptive congenital syphilis and to assess the role of maternal treatment (administration of penicillin to the mother at least 1 month before delivery) on the serologic results at the time of delivery. The serologic results from all live deliveries complicated by a positive maternal and/or neonatal test for syphilis during a 12-month period were compared using χ2 analysis and multiple comparisons for proportions. Of 3306 livebirths, 73 (2.2%) were complicated by a positive maternal or neonatal serology. At delivery, the serologic test was positive in 68 (94%) of 72 maternal sera, 30 (50%) of 60 cord sera, and 43 (63%) of 68 neonatal sera. In the absence of maternal treatment, 95% of the maternal sera, 66% of the cord blood samples, and 86% of the neonatal sera were positive. If the mother had been treated, 94% of maternal sera, 36% of cord sera, and 39% of neonatal sera were positive. Cord blood and neonatal sera appear to be inferior to maternal sera for detecting prenatal exposure to syphilis. Cord serology is also inferior to neonatal serology at 2 to 3 days of age. The most effective way to identify newborns at risk for congenital syphilis is to obtain a maternal serologic diagnosis during pregnancy and to test maternal and neonatal sera at delivery.

CAPACITY OF THYROXINE-BINDING GLOBULIN TO BIND TRIIODOTHYRONINE AND THYROXINE IN MATERNAL AND CORD BLOOD

PEDIATRICS ◽  
1962 ◽  
Vol 29 (3) ◽  
pp. 369-375
Author(s):  
William M. Michener ◽  
W. Newlon Tauxe ◽  
Alvin B. Hayles
Keyword(s):  
Cord Blood ◽  
Normal Values ◽  
Binding Capacity ◽  
Quantitative Difference ◽  
Maternal Blood ◽  
Blood Samples ◽  
Thyroxine Binding Globulin

Normal values for the measurement of thyroidal function using the erythrocytic uptake of I131-labeled triiodothyronine and the thyroxine-binding capacity of the inter-alpha globulin were established. Paired maternal and cord blood samples collected at the time of delivery were studied with these methods. The erythrocytic uptake of labeled hormone was increased in cord blood as compared to maternal blood. Cord blood apparently binds exogenous triiodothyronine in a different manner than it does exogenous thyroxine. Whether this is a qualitative or quantitative difference was not shown in this study.

scholarly journals Cord blood buffy coat DNA methylation is comparable to whole cord blood methylation

2017 ◽  
Author(s):  
John Dou ◽  
Rebecca J. Schmidt ◽  
Kelly S. Benke ◽  
Craig Newschaffer ◽  
Irva Hertz-Picciotto ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Blood Cell ◽  
Cord Blood ◽  
Whole Blood ◽  
Cell Types ◽  
Buffy Coat ◽  
Sample Type ◽  
Blood Samples ◽  
Cell Composition ◽  
Cell Counts

AbstractBackgroundCord blood DNA methylation is associated with numerous health outcomes and environmental exposures. Whole cord blood DNA reflects all nucleated blood cell types, while centrifuging whole blood separates red blood cells by generating a white blood cell buffy coat. Both sample types are used in DNA methylation studies. Cell types have unique methylation patterns and processing can impact cell distributions, which may influence comparability.ObjectivesTo evaluate differences in cell composition and DNA methylation between buffy coat and whole cord blood samples.MethodsCord blood DNA methylation was measured with the Infinium EPIC BeadChip (Illumina) in 8 individuals, each contributing buffy coat and whole blood samples. We analyzed principal components (PC) of methylation, performed hierarchical clustering, and computed correlations of mean-centered methylation between pairs. We conducted moderated t-tests on single sites and estimated cell composition.ResultsDNA methylation PCs were associated with individual (PPC1=1.4x10-9; PPC2=2.9x10-5; PPC3=3.8x10-5; PPC4=4.2x10-6; PPC5=9.9x10-13), and not with sample type (PPC1-5>0.7). Samples hierarchically clustered by individual. Pearson correlations of mean-centered methylation between paired individual samples ranged from r=0.66 to r=0.87. No individual site significantly differed between buffy coat and whole cord blood when adjusting for multiple comparisons (5 sites had unadjusted P<10-5). Estimated cell type proportions did not differ by sample type (P=0.86), and estimated cell counts were highly correlated between paired samples (r=0.99).ConclusionsDifferences in methylation and cell composition between buffy coat and whole cord blood are much lower than inter-individual variation, demonstrating that both sample preparation types can be analytically combined and compared.

scholarly journals The biometrics techniques for the assessment of the degree of adoption of toxic and essential elements

2018 ◽  
Vol 59 (1) ◽  
pp. 56-66
Author(s):  
Nevenka Mijatović ◽  
Lato Pezo ◽  
Anja Terzić ◽  
Snežana Šerbula ◽  
Renata Kovačević
Keyword(s):  
Essential Elements ◽  
Toxic And Essential Elements

Urinary stones as a novel matrix for human biomonitoring of toxic and essential elements

2015 ◽  
Vol 38 (1) ◽  
pp. 133-143 ◽  
Author(s):  
J. Kuta ◽  
S. Smetanová ◽  
D. Benová ◽  
T. Kořistková ◽  
J. Machát
Keyword(s):  
Human Biomonitoring ◽  
Essential Elements ◽  
Urinary Stones ◽  
Toxic And Essential Elements

scholarly journals Plasma proteome changes in cord blood samples from preterm infants

2018 ◽  
Vol 38 (9) ◽  
pp. 1182-1189 ◽  
Author(s):  
Maciej Suski ◽  
Renata Bokiniec ◽  
Monika Szwarc-Duma ◽  
Józef Madej ◽  
Beata Bujak-Giżycka ◽  
...  
Keyword(s):  
Cord Blood ◽  
Preterm Infants ◽  
Plasma Proteome ◽  
Blood Samples ◽  
Proteome Changes
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