Carbosilane dendrimers peripherally functionalized with dansyl fluorescence tags and their cellular internalization studies

2009 ◽  
Vol 7 (15) ◽  
pp. 3079 ◽  
Author(s):  
Paula Ortega ◽  
Ma Jesús Serramía ◽  
Rafael Samaniego ◽  
F. Javier de la Mata ◽  
Rafael Gomez ◽  
...  
Keyword(s):  
Cellular Internalization ◽  
Carbosilane Dendrimers ◽  
Fluorescence Tags

A conformational tweak for enhanced cellular internalization, photobleaching resistance and prolonged imaging efficacy

2020 ◽  
Vol 56 (94) ◽  
pp. 14861-14864
Author(s):  
Niranjan Meher ◽  
Anil Parsram Bidkar ◽  
Debasish Barman ◽  
Siddhartha Sankar Ghosh ◽  
Parameswar Krishnan Iyer
Keyword(s):  
Self Assembly ◽  
Biological Activities ◽  
Cellular Internalization ◽  
Molecular Systems ◽  
Simple Strategy ◽  
Fine Tune

A simple strategy of conformational manipulation has been unveiled to fine-tune the photophysical and supramolecular self-assembly properties of small molecular systems, which subsequently regulates their biological activities.

Cellular internalization of lactoferrin in intestinal epithelial cells

BioMetals ◽  
2004 ◽  
Vol 17 (3) ◽  
pp. 311-315 ◽  
Author(s):  
Kinya Ashida ◽  
Hajime Sasaki ◽  
Yasushi A. Suzuki ◽  
Bo Lönnerdal
Keyword(s):  
Epithelial Cells ◽  
Intestinal Epithelial Cells ◽  
Cellular Internalization ◽  
Intestinal Epithelial

Cellular internalization and stress response of ingested amorphous silica nanoparticles in the midgut of Drosophila melanogaster

2013 ◽  
Vol 1830 (1) ◽  
pp. 2256-2266 ◽  
Author(s):  
Ashutosh Pandey ◽  
Swati Chandra ◽  
Lalit Kumar Singh Chauhan ◽  
Gopeshwar Narayan ◽  
Debapratim Kar Chowdhuri
Keyword(s):  
Drosophila Melanogaster ◽  
Stress Response ◽  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Cellular Internalization

scholarly journals Antiviral mechanism of polyanionic carbosilane dendrimers against HIV-1

2016 ◽  
pp. 1281 ◽  
Author(s):  
Mariangeles Angeles Munoz-Fernandez ◽  
Enrique Vacas-Córdoba ◽  
Marek Maly ◽  
Francisco Javier de la Mata ◽  
Rafael Gómez ◽  
...  
Keyword(s):  
Carbosilane Dendrimers ◽  
Antiviral Mechanism ◽  
Hiv 1

Cellular Internalization and in Vivo Tracking of Thermosensitive Luminescent Micelles Based on Luminescent Lanthanide Chelate

ACS Nano ◽  
2008 ◽  
Vol 2 (1) ◽  
pp. 125-133 ◽  
Author(s):  
Yong-Yong Li ◽  
Han Cheng ◽  
Zhi-Guo Zhang ◽  
Chang Wang ◽  
Jing-Ling Zhu ◽  
...  
Keyword(s):  
Cellular Internalization ◽  
Lanthanide Chelate

scholarly journals Design considerations for mesoporous silica nanoparticulate systems in facilitating biomedical applications

2014 ◽  
Vol 1 (1) ◽  
Author(s):  
Diti Desai ◽  
Didem Sen Karaman ◽  
Neeraj Prabhakar ◽  
Sina Tadayon ◽  
Alain Duchanoy ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Biomedical Applications ◽  
Common Ground ◽  
Particle System ◽  
Mesoporous Silica Nanoparticles ◽  
Cellular Internalization ◽  
Design Considerations ◽  
Design Options ◽  
Nanoparticulate Systems

AbstractMesoporous silica nanoparticles (MSNs) have advanced to the forefront of multifunctional nanoparticulate systems in nanomedicine, owing to this highly fexible materials platform enabling a multitude of design options, often in a modular fashion. Drug delivery ability, detectability via diferent imaging modalities, and stimuliresponsiveness are often combined into one particle system. Very sophisticated and versatile designs along with impressive demonstrations of applicability have been reported to date, but a common ground when it comes to some critical considerations valid for any nanoparticle intended for biomedical purposes is lacking to some degree. In this study, we attempt to take a glance at some of the most crucial aspects of biomedical nanoparticulate design and relate how they apply specifically toMSNs. These considerations include fuorophore labeling and leaching with respect to immobilization to MSNs, the surrounding conditions, carrier biodegradability, and surface coating. Surface modifcation strategies and surface charge tuning are further considered in conjunction to the relative amount of cellular uptake and serum protein adsorption. Cellular internalization routes and biological techniques used to evaluate especially in vitro biobehavior are discussed. Our attempt is hereby to draw attention to some of the most frequently occurring issues to be considered in the design of MSN systems for biomedical applications

scholarly journals Dialyzable Carbosilane Dendrimers as Soluble Supports for the Functionalization of Pyridine Fragments via Palladium-Catalyzed Coupling Reactions.

ChemInform ◽  
2005 ◽  
Vol 36 (20) ◽  
Author(s):  
Jerome Le Notre ◽  
Judith J. Firet ◽  
Leo A. J. M. Sliedregt ◽  
Bart J. van Steen ◽  
Gerard van Koten ◽  
...  
Keyword(s):  
Coupling Reactions ◽  
Carbosilane Dendrimers ◽  
Palladium Catalyzed
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