scholarly journals Multipoint viscosity measurements in microfluidic channels using optical tweezers

Lab on a Chip ◽  
2009 ◽  
Vol 9 (14) ◽  
pp. 2059 ◽  
Author(s):  
Stephen Keen ◽  
Alison Yao ◽  
Jonathan Leach ◽  
Roberto Di Leonardo ◽  
Chris Saunter ◽  
...  
2000 ◽  
Vol 657 ◽  
Author(s):  
Cengiz S. Ozkan ◽  
Erhan Ata ◽  
Mihrimah Ozkan ◽  
Sadik C. Esener

ABSTRACTWe describe a technique for trapping and manipulation of inorganic and organic objects in microfluidic channels, based on photonic momentum transfer using an optical tweezers arrangement. Microfluidic devices have been fabricated by polydimethylsiloxane (PDMS) elastomer molding of patterns lithographically defined on a thick negative photoresist. Polystyrene microspheres dispersed in water were transferred into the fluidic channels using a syringe pump. Microspheres and live biological cells are trapped and redirected by optical manipulation within the fluidic channels. Optical trapping and patterning will have applications in creation of active cellular arrays for cell biology research, tissue engineering, cell sorting and drug discovery.


Author(s):  
Weronika Lamperska ◽  
Sławomir Drobczyński ◽  
Michał Nawrot ◽  
Piotr Wasylczyk ◽  
Jan Masajada

Manipulation of micro- and nano-sized objects with optical tweezers is a well established, albeit still evolving technique. While many objects can be trapped directly with focused laser beam(s), for some applications indirect manipulation with tweezers-operated tools is preferred. We introduce a simple, versatile micro-tool operated with holographic optical tweezers. The 40 µm long dumbbell-shaped tool, fabricated with two-photon laser 3D photolithography has two beads for efficient optical trapping and a probing spike on one end. We demonstrate fluids viscosity measurements and vibration detection as examples of possible applications.


2005 ◽  
Vol 76 (11) ◽  
pp. 115105 ◽  
Author(s):  
G. Pesce ◽  
A. Sasso ◽  
S. Fusco

2018 ◽  
Vol 8 (9) ◽  
pp. 1522 ◽  
Author(s):  
Min-Cheng Zhong ◽  
Ai-Yin Liu ◽  
Rong Zhu

Optical tweezers can manipulate micro-particles, which have been widely used in various applications. Here, we experimentally demonstrate that optical tweezers can assemble the micro-particles to form stable structures at the glass–solution interface in this paper. Firstly, the particles are driven by the optical forces originated from the diffraction fringes, which of the trapping beam passing through an objective with limited aperture. The particles form stable ring structures when the trapping beam is a linearly polarized beam. The particle distributions in the transverse plane are affected by the particle size and concentration. Secondly, the particles form an incompact structure as two fan-shaped after the azimuthally polarized beam passing through a linear polarizer. Furthermore, the particles form a compact structure when a radially polarized beam is used for trapping. Thirdly, the particle patterns can be printed steady at the glass surface in the salt solution. At last, the disadvantage of diffraction traps is discussed in application of optical tweezers. The aggregation of particles at the interfaces seriously affects the flowing of particles in microfluidic channels, and a total reflector as the bottom surface of sample cell can avoid the optical tweezers induced particle patterns at the interface. The optical trapping study utilizing the diffraction gives an interesting method for binding and assembling microparticles, which is helpful to understand the principle of optical tweezers.


2008 ◽  
Author(s):  
Andrea Kroner ◽  
Carolin Schneck ◽  
Fernando Rinaldi ◽  
Rudolf Rösch ◽  
Rainer Michalzik

2004 ◽  
Vol 51 (3) ◽  
pp. 409-414 ◽  
Author(s):  
P. Jordan ◽  
J. Leach ◽  
M. J. Padgett ◽  
J. Cooper ◽  
G. Sinclair
Keyword(s):  

Equipment ◽  
2006 ◽  
Author(s):  
C. Yang ◽  
G. Y. Tang ◽  
D. G. Yan ◽  
H. Q. Gong ◽  
John C. Chai ◽  
...  

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