A mass spectrometry-based method to measure dialkylphosphate degradation products of organophosphorous insecticides in dust and orange juice

2009 ◽  
Vol 11 (7) ◽  
pp. 1345 ◽  
Author(s):  
Gayanga Weerasekera ◽  
Kimberly D. Smith ◽  
Lesliam Quirós-Alcalá ◽  
Carolina Fernandez ◽  
Asa Bradman ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Orange Juice ◽  
Degradation Products ◽  
Organophosphorous Insecticides

scholarly journals Characterization and Study on Fragmentation Pathways of a Novel Nerve Agent, ‘Novichok (A234)’, in Aqueous Solution by Liquid Chromatography–Tandem Mass Spectrometry

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1059
Author(s):  
Jin Young Lee ◽  
Kyoung Chan Lim ◽  
Hyun Suk Kim
Keyword(s):  
Mass Spectrometry ◽  
Aqueous Solution ◽  
Liquid Chromatography ◽  
Degradation Products ◽  
Aqueous Sample ◽  
Tandem Mass ◽  
Aqueous Samples ◽  
Fragmentation Pathways ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

As a first step toward studying the properties of Novichok (ethyl (1-(diethylamino)ethylidene)phosphoramidofluoridate (A234)), we investigated its degradation products and fragmentation pathways in aqueous solution at different pH levels by liquid chromatography–tandem mass spectrometry. A234 was synthesized in our laboratory and characterized by nuclear magnetic resonance spectroscopy. Three sets of aqueous samples were prepared at different pH levels. A stock solution of A234 was prepared in acetonitrile at a concentration of 1 mg/mL and stored at −20 °C until use. Aqueous samples (0.1 mg/mL) were prepared by diluting the stock solution with deionized water. The acidic aqueous sample (pH = 3.5) and basic aqueous sample (pH = 9.4) were prepared using 0.01 M acetic acid and 0.01 M potassium carbonate, respectively. The analysis of the fragmentation patterns and degradation pathways of A234 showed that the same degradation products were formed at all pH levels. However, the hydrolysis rate of A234 was fastest under acidic conditions. In all three conditions, the fragmentation pattern and the major degradation product of A234 were determined. This information will be applicable to studies regarding the decontamination of Novichok and the trace analysis of its degradation products in various environmental matrices.

Matrix-matched standards for the quantification of elemental lithium ion battery degradation products deposited on carbonaceous negative electrodes using pulsed-glow discharge-sector field-mass spectrometry

2017 ◽  
Vol 32 (10) ◽  
pp. 1862-1867 ◽  
Author(s):  
Marco Evertz ◽  
Timo Schwieters ◽  
Markus Börner ◽  
Martin Winter ◽  
Sascha Nowak
Keyword(s):  
Mass Spectrometry ◽  
Glow Discharge ◽  
Lithium Ion Battery ◽  
Degradation Products ◽  
Lithium Ion ◽  
Field Mass ◽  
Pulsed Glow Discharge ◽  
Negative Electrodes ◽  
Battery Degradation ◽  
Sector Field Mass Spectrometry

A glow discharge-sector field-mass spectrometry (GD-SF-MS) method using matrix-matched self-prepared carbonaceous standards for elemental battery degradation products of (NCM111) electrodes was developed.

Sign in / Sign up

Export Citation Format

Share Document