Rhodium-catalyzed asymmetric transfer hydrogenation of alkyl and aryl ketones in aqueous media

2008 ◽  
Vol 10 (8) ◽  
pp. 832 ◽  
Author(s):  
Katrin Ahlford ◽  
Jesper Lind ◽  
Lena Mäler ◽  
Hans Adolfsson
Keyword(s):  
Aqueous Media ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Aryl Ketones

scholarly journals Simple 1,3-diamines and their application as ligands in ruthenium(ii) catalysts for asymmetric transfer hydrogenation of aryl ketones

2015 ◽  
Vol 39 (5) ◽  
pp. 3792-3800 ◽  
Author(s):  
Giorgio Facchetti ◽  
Raffaella Gandolfi ◽  
Marco Fusè ◽  
Daniele Zerla ◽  
Edoardo Cesarotti ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Transfer Hydrogenation ◽  
Efficient Synthesis ◽  
Asymmetric Transfer Hydrogenation ◽  
Aryl Ketones

A new efficient synthesis of 1,3-diamines was realized and their ruthenium(ii) complexes were studied in ATH in aqueous media.

scholarly journals Design of Iridium N-Heterocyclic Carbene Amino Acid Catalysts for Asymmetric Transfer Hydrogenation of Aryl Ketones

Catalysts ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 671
Author(s):  
Chad M. Bernier ◽  
Joseph S. Merola
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Enantiomeric Excess ◽  
Transfer Hydrogenation ◽  
Acid Catalysts ◽  
Asymmetric Transfer Hydrogenation ◽  
Reaction Conditions ◽  
Chiral Complexes ◽  
Acetophenone Derivatives ◽  
Aryl Ketones

A series of chiral complexes of the form Ir(NHC)2(aa)(H)(X) (NHC = N-heterocyclic carbene, aa = chelated amino acid, X = halide) was synthesized by oxidative addition of -amino acids to iridium(I) bis-NHC compounds and screened for asymmetric transfer hydrogenation of ketones. Following optimization of the reaction conditions, NHC, and amino acid ligands, high enantioselectivity was achieved when employing the Ir(IMe)2(l-Pro)(H)(I) catalyst (IMe = 1,3-dimethylimidazol-2-ylidene), which asymmetrically reduces a range of acetophenone derivatives in up to 95% enantiomeric excess.

ChemInform Abstract: 8-Amino-5,6,7,8-tetrahydroquinolines as Ligands in Iridium(III) Catalysts for the Reduction of Aryl Ketones by Asymmetric Transfer Hydrogenation (ATH).

ChemInform ◽  
2015 ◽  
Vol 46 (4) ◽  
pp. no-no
Author(s):  
Daniele Zerla ◽  
Giorgio Facchetti ◽  
Marco Fuse ◽  
Michela Pellizzoni ◽  
Carlo Castellano ◽  
...  
Keyword(s):  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Aryl Ketones
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