Syntheses and bio-activities of the l-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases

2006 ◽  
Vol 4 (6) ◽  
pp. 1131 ◽  
Author(s):  
Keith Clinch ◽  
Gary B. Evans ◽  
George W. J. Fleet ◽  
Richard H. Furneaux ◽  
Stephen W. Johnson ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside ◽  
Transition State Analogue ◽  
Transition State Analogue Inhibitors ◽  
Nucleoside Phosphorylases

Synthesis of Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase and N-Riboside Hydrolases

Tetrahedron ◽  
2000 ◽  
Vol 56 (19) ◽  
pp. 3053-3062 ◽  
Author(s):  
Gary B. Evans ◽  
Richard H. Furneaux ◽  
Graeme J. Gainsford ◽  
Vern L. Schramm ◽  
Peter C. Tyler
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogue ◽  
Transition State Analogue Inhibitors

scholarly journals l-Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside Phosphorylase

2008 ◽  
Vol 130 (3) ◽  
pp. 842-844 ◽  
Author(s):  
Agnes Rinaldo-Matthis ◽  
Andrew S. Murkin ◽  
Udupi A. Ramagopal ◽  
Keith Clinch ◽  
Simon P. H. Mee ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogue ◽  
Transition State Analogue Inhibitors

scholarly journals Transition State Analogue Discrimination by Related Purine Nucleoside Phosphorylases

2006 ◽  
Vol 128 (22) ◽  
pp. 7126-7127 ◽  
Author(s):  
Erika A. Taylor Ringia ◽  
Peter C. Tyler ◽  
Gary B. Evans ◽  
Richard H. Furneaux ◽  
Andrew S. Murkin ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside ◽  
Transition State Analogue ◽  
Nucleoside Phosphorylases

scholarly journals Transition State Analogue Inhibitors of Purine Nucleoside Phosphorylase fromPlasmodium falciparum

2001 ◽  
Vol 277 (5) ◽  
pp. 3219-3225 ◽  
Author(s):  
Gregory A. Kicska ◽  
Peter C. Tyler ◽  
Gary B. Evans ◽  
Richard H. Furneaux ◽  
Kami Kim ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogue ◽  
Transition State Analogue Inhibitors
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