8-Aza-immucillins as Transition-State Analogue Inhibitors of Purine Nucleoside Phosphorylase and Nucleoside Hydrolases

2003 ◽  
Vol 46 (1) ◽  
pp. 155-160 ◽  
Author(s):  
Gary B. Evans ◽  
Richard H. Furneaux ◽  
Graeme J. Gainsford ◽  
John C. Hanson ◽  
Gregory A. Kicska ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogue ◽  
Transition State Analogue Inhibitors ◽  
Nucleoside Hydrolases

Synthesis of Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase and N-Riboside Hydrolases

Tetrahedron ◽  
2000 ◽  
Vol 56 (19) ◽  
pp. 3053-3062 ◽  
Author(s):  
Gary B. Evans ◽  
Richard H. Furneaux ◽  
Graeme J. Gainsford ◽  
Vern L. Schramm ◽  
Peter C. Tyler
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogue ◽  
Transition State Analogue Inhibitors

scholarly journals l-Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside Phosphorylase

2008 ◽  
Vol 130 (3) ◽  
pp. 842-844 ◽  
Author(s):  
Agnes Rinaldo-Matthis ◽  
Andrew S. Murkin ◽  
Udupi A. Ramagopal ◽  
Keith Clinch ◽  
Simon P. H. Mee ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogue ◽  
Transition State Analogue Inhibitors

scholarly journals Transition State Analogue Inhibitors of Purine Nucleoside Phosphorylase fromPlasmodium falciparum

2001 ◽  
Vol 277 (5) ◽  
pp. 3219-3225 ◽  
Author(s):  
Gregory A. Kicska ◽  
Peter C. Tyler ◽  
Gary B. Evans ◽  
Richard H. Furneaux ◽  
Kami Kim ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogue ◽  
Transition State Analogue Inhibitors

Purine Nucleoside Phosphorylase fromMycobacterium tuberculosis. Analysis of Inhibition by a Transition-State Analogue and Dissection by Parts†

Biochemistry ◽  
2001 ◽  
Vol 40 (28) ◽  
pp. 8196-8203 ◽  
Author(s):  
Luiz A. Basso ◽  
Diogenes S. Santos ◽  
Wuxian Shi ◽  
Richard H. Furneaux ◽  
Peter C. Tyler ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogue

Atomic Dissection of the Hydrogen Bond Network for Transition-State Analogue Binding to Purine Nucleoside Phosphorylase†

Biochemistry ◽  
2002 ◽  
Vol 41 (49) ◽  
pp. 14489-14498 ◽  
Author(s):  
Greg A. Kicska ◽  
Peter C. Tyler ◽  
Gary B. Evans ◽  
Richard H. Furneaux ◽  
Wuxian Shi ◽  
...  
Keyword(s):  
Hydrogen Bond ◽  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Hydrogen Bond Network ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogue ◽  
Bond Network
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