Gradient semi-interpenetrating polymer networks based on polyurethane and poly(vinyl pyrrolidone)

2005 ◽  
Vol 15 (4) ◽  
pp. 499 ◽  
Author(s):  
Lyudmila V. Karabanova ◽  
Sergey V. Mikhalovsky ◽  
Andrew W. Lloyd ◽  
Gisele Boiteux ◽  
Lyudmila M. Sergeeva ◽  
...  
Keyword(s):  
Polymer Networks ◽  
Interpenetrating Polymer Networks ◽  
Vinyl Pyrrolidone ◽  
Poly Vinyl Pyrrolidone

scholarly journals Optimization of swelling response of pH sensitive hydrogels using Box-Behnken design

2018 ◽  
Author(s):  
Fereshteh Shokri ◽  
Pouneh Ebrahimi ◽  
Soheyla Honary
Keyword(s):  
Polymer Networks ◽  
Three Dimensional ◽  
Statistical Design ◽  
Ph Sensitive ◽  
Vinyl Pyrrolidone ◽  
Swelling Properties ◽  
Screening Design ◽  
Statistical Screening ◽  
Poly Vinyl Pyrrolidone ◽  
Responsive Hydrogels

AbstractHydrogels are three-dimensional crosslinked hydrophilic polymer networks capable of swelling or de-swelling reversibly in water and retaining a large volume of liquid in swollen state. Hydrogels can be designed with controllable responses to shrink or expand with changes in external environmental conditions. Among stimulisensitive hydrogels, the pH-sensitive ones are widely-studied and used. Despite these advances, we currently lack a systematic way to optimize the synthesis protocols. Here we propose to use techniques from chemometrics, namely Box–Behnken statistical screening design to optimize the chemical composition of pH-responsive hydrogels for an improved responsiveness as quantified by swelling index. Polymer blends were prepared by mixing different suitable volume of pvp (poly vinyl pyrrolidone) and chitosan aqueous solution in order to obtain a mixture, glutardialdehyde solution was added as crosslinkers to the chitosan/pvp mixture to form semi-IPN(semi-interpenetrating polymeric hydrogel). The pH-dependent swelling properties have been measured and used to obtain a regression model. We characterized the descriptive and predictive abilities of our model. We found a remarkable correlation (correlation coefficient = 0.954) between the observed responses and the responses predicted by the model. Our results demonstrate that Box-Behnken is an appropriate statistical design that can be successfully used in the development of pH-sensitive hydrogels with a predictable swelling ratio. This technology will remarkably reduce the time and cost that is needed for chemical synthesis of hydrogels with a desired pH-sensitivity.

scholarly journals Potential Application of a Visible Light-Induced Photocured Hydrogel Film as a Wound Dressing Material

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Aazadehsadat Hashemi Doulabi ◽  
Hamid Mirzadeh ◽  
Nasrin Samadi ◽  
Shadab Bagheri-Khoulenjani ◽  
Mohammad Atai ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Potential Application ◽  
Wound Dressing ◽  
Polymer Networks ◽  
Interpenetrating Polymer Networks ◽  
Vinyl Pyrrolidone ◽  
Cross Linking ◽  
Hydrogel Film ◽  
Swelling Degree ◽  
Hydrogel Films

The objective of this work was to prepare hydrogel films, as semi-interpenetrating polymer networks (semi-IPN), based on polyethylene glycol-co-fumarate (PEGF) and chitosan (Ch) blends. Hydrogel films were prepared by free radical cross-linking of PEGF, an unsaturated aliphatic polyester, in the presence of N-vinyl pyrrolidone (NVP), camphorquinone (CQ), and N,N-dimethyl-p-toluidine (DMPT) as a cross-linking, photoinitiating, and accelerating agent, respectively. The effect of NVP concentration on physicochemical and biological properties of semi-IPN film properties was evaluated. The sol fraction, water vapor transmission rate, and swelling degree of the hydrogel films were also investigated. Antibacterial activity against S. aureus was observed for the photocured blend hydrogels of Ch/PEGF with no toxicity to L929 cells according to the cell viability assays. Blend hydrogel films showing 600 ± 88% of equilibrium swelling degree in water and the lowest sol fraction (3.14 ± 1.22%) were obtained at 20 wt% of NVP content whilst preserving their own cytocompatibility and antibacterial activity. Therefore, this formulation was considered as an optimal semi-IPN blend hydrogel film composition with potential application for wound dressing.

scholarly journals The microscopic distribution of hydrophilic polymers in interpenetrating polymer networks (IPNs) of medical grade silicone

Polymer ◽  
2021 ◽  
Vol 224 ◽  
pp. 123671
Author(s):  
Gregory N. Smith ◽  
Erik Brok ◽  
Martin Schmiele ◽  
Kell Mortensen ◽  
Wim G. Bouwman ◽  
...  
Keyword(s):  
Polymer Networks ◽  
Interpenetrating Polymer Networks ◽  
Hydrophilic Polymers ◽  
Microscopic Distribution ◽  
Medical Grade

scholarly journals ALD coating of centrifugally spun polymeric fibers and postannealing: case study for nanotubular TiO2 photocatalyst

2021 ◽  
Author(s):  
Martina Rihova ◽  
Oksana Yurkevich ◽  
Martin Motola ◽  
Ludek Hromadko ◽  
Zdeněk Spotz ◽  
...  
Keyword(s):  
Atomic Layer Deposition ◽  
Atomic Layer ◽  
Vinyl Pyrrolidone ◽  
Tio2 Photocatalyst ◽  
Polymeric Fibers ◽  
Layer Deposition ◽  
Centrifugal Spinning ◽  
Poly Vinyl Pyrrolidone

This work describes the synthesis of highly photocatalytically active TiO2 tubes (TiTBs) by combining centrifugal spinning and atomic layer deposition (ALD). Poly(vinyl pyrrolidone) (PVP) fibers were first produced by centrifugal...

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