1H-NMR spectroscopic studies of paramagnetic superstructured iron(III) porphyrinsThis article is dedicated to the memory of Professor Michel Momenteau of Institut Curie.Abbreviations. 1D and 2D: one-dimensional and two-dimensional; COSY: correlated spectroscopy; NOESY: nuclear Overhauser effect spectroscopy; TPP: 5,10,15,20-tetraphenylporphyrinate dianion.

2002 ◽  
Vol 26 (3) ◽  
pp. 323-329 ◽  
Author(s):  
Hermas R. Jiménez ◽  
José M. Moratal ◽  
Bernard Loock
Keyword(s):  
1H Nmr ◽  
Nuclear Overhauser Effect ◽  
Spectroscopic Studies ◽  
Two Dimensional ◽  
One Dimensional ◽  
Overhauser Effect ◽  
Nuclear Overhauser

Homonuclear one- and two-dimensional nuclear Overhauser effect experiments and spin-echo correlated spectroscopy. Application to prostaglandin E1 and 6-keto-prostaglandin E1

1982 ◽  
Vol 60 (20) ◽  
pp. 2617-2624 ◽  
Author(s):  
George Kotovych ◽  
Gerdy H. M. Aarts
Keyword(s):  
Magnetic Resonance ◽  
Prostaglandin E1 ◽  
Nuclear Overhauser Effect ◽  
Spin Echo ◽  
Proton Magnetic Resonance Spectrum ◽  
Prostaglandin E ◽  
Two Dimensional ◽  
One Dimensional ◽  
Overhauser Effect ◽  
Nuclear Overhauser

Nuclear Overhauser effect one-dimensional and two-dimensional nuclear magnetic resonance experiments are reported for prostaglandin E1. The two-dimensional nuclear Overhauser effect measurements are combined with spin-echo correlated spectroscopy in order to assign the complete high-field proton magnetic resonance spectrum of 6-keto-prostaglandin E1. The advantages of these two-dimensional techniques are illustrated in these studies. It is also observed that the 6-keto-prostaglandin E1 H-10α proton is substituted more readily by deuterium than are the other protons α to the keto groups.

1H NMR studies of [N-MeAib1, Tyr(Me)4]ANGII and [N-MeAib1, Tyr(Me)4, Ile8]ANGII in dimethylsulfoxide by nuclear Overhauser effect (NOE) enhancement spectroscopy: cis-trans Isomerism of the His-Pro bond

1990 ◽  
Vol 55 (4) ◽  
pp. 1106-1111 ◽  
Author(s):  
John Matsoukas ◽  
Paul Cordopatis ◽  
Raghav Yamdagni ◽  
Graham J. Moore
Keyword(s):  
1H Nmr ◽  
Nuclear Overhauser Effect ◽  
Nmr Studies ◽  
Restricted Rotation ◽  
Overhauser Effect ◽  
Major Isomer ◽  
Conformational Properties ◽  
Nuclear Overhauser

The conformational properties of the Sarmesin analogues [N-MeAib1, Tyr(Me)4]ANGII and [N-MeAib1, Tyr(Me)4, Ile8]ANGII in hexadeutero-dimethysulfoxide were investigated by Nuclear Overhauser Effect (NOE) Enhancement Studies. Cis-trans isomers (ratio 1 : 6) due to restricted rotation of the His-Pro bond were observed. Interresidue interactions between the His Cα proton and the two Pro Cδ protons revealed that the major isomer was the trans.

scholarly journals Benderamide A, a Cyclic Depsipeptide from a Singapore Collection of Marine Cyanobacterium cf. Lyngbya sp.

Marine Drugs ◽  
2018 ◽  
Vol 16 (11) ◽  
pp. 409 ◽  
Author(s):  
Chi Ding ◽  
Ji Ong ◽  
Hui Goh ◽  
Cynthia Coffill ◽  
Lik Tan
Keyword(s):  
Breast Cancer Cells ◽  
Nuclear Overhauser Effect ◽  
2D Nmr ◽  
Marine Cyanobacterium ◽  
One Dimensional ◽  
Mechanistic Pathway ◽  
Overhauser Effect ◽  
Cyclic Depsipeptide ◽  
Nuclear Overhauser ◽  
Related Compounds

Benderamide A (1), a (S)-2,2-dimethyl-3-hydroxy-7-octynoic acid (S-Dhoya)-containing cyclic depsipeptide that belongs to the kulolide superfamily, was isolated from a Singapore collection of cf. Lyngbya sp. marine cyanobacterium using a bioassay-guided approach. While the planar structure of 1 was elucidated using a combination of 1D and 2D NMR experiments and MS analysis, the absolute configuration was subsequently achieved using the results obtained from Marfey’s analysis, comparative analysis of nuclear overhauser effect spectroscopy (NOESY) with the known compound 3, and one dimensional-nuclear overhauser effect (1D-NOE). Although 1 did not display antiproliferative activity against MCF7 breast cancer cells, the presence of an Ala instead of Gly suggests a possible mechanistic pathway to explain the consequential decrease in cytotoxicity compared to the closely related 2. In addition, results obtained from an LC–MS/MS-based molecular networking algorithm revealed two other closely related compounds encouraging further identification and isolation from the same marine cyanobacterium extract.

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