Multiple ligand transfer to planar-chiral cyclopentadienylruthenium complexes inducing metal-centered chirality

2000 ◽  
pp. 2337-2338 ◽  
Author(s):  
Taku Katayama ◽  
Yuji Matsushima ◽  
Kiyotaka Onitsuka ◽  
Shigetoshi Takahashi
Keyword(s):  
Ligand Transfer ◽  
Multiple Ligand

scholarly journals Apohemoglobin-haptoglobin complex attenuates the pathobiology of circulating acellular hemoglobin and heme

2020 ◽  
Vol 318 (5) ◽  
pp. H1296-H1307 ◽  
Author(s):  
Carlos J. Munoz ◽  
Ivan S. Pires ◽  
Jin Hyen Baek ◽  
Paul W. Buehler ◽  
Andre F. Palmer ◽  
...  
Keyword(s):  
Therapeutic Strategy ◽  
Capillary Density ◽  
Microvascular Blood Flow ◽  
Systemic Hypertension ◽  
Proof Of Concept ◽  
Heme Transfer ◽  
Ligand Transfer ◽  
Novel Therapeutic

This study highlights the apoHb-Hp complex as a novel therapeutic strategy to attenuate the adverse systemic and microvascular responses to intravascular Hb and heme exposure. In vitro and in vivo Hb exchange and heme transfer experiments demonstrated proof-of-concept Hb/heme ligand transfer to apoHb-Hp. The apoHb-Hp complex reverses Hb- and heme-induced systemic hypertension and microvascular vasoconstriction, preserves microvascular blood flow, and functional capillary density. In summary, the unique properties of the apoHb-Hp complex prevent adverse systemic and microvascular responses to Hb and heme-albumin exposure and introduce a novel therapeutic approach to facilitate simultaneous removal of extracellular Hb and heme.

scholarly journals On the importance of composite protein multiple ligand interactions in protein pockets

2016 ◽  
Vol 38 (15) ◽  
pp. 1252-1259 ◽  
Author(s):  
Sam Tonddast-Navaei ◽  
Bharath Srinivasan ◽  
Jeffrey Skolnick
Keyword(s):  
Ligand Interactions ◽  
Protein Pockets ◽  
Multiple Ligand

scholarly journals Direct synthesis of doubly deprotonated, dearomatised lutidine PNP Cr and Zr pincer complexes based on isolated K and Li ligand transfer reagents

2016 ◽  
Vol 45 (7) ◽  
pp. 2800-2804 ◽  
Author(s):  
Thomas Simler ◽  
Gilles Frison ◽  
Pierre Braunstein ◽  
Andreas A. Danopoulos
Keyword(s):  
Direct Synthesis ◽  
Pincer Complexes ◽  
Zirconium Complexes ◽  
Ligand Transfer

Double deprotonation of a hybrid bis(phosphino)picoline ligand yields lithium or potassium pincer salts with dearomatised lutidine backbones that afford unusual chromium and zirconium complexes by transmetallation.

Polymers with Multiple Ligand Sites for Metal Extractions in Dense-Phase Carbon Dioxide†

2001 ◽  
Vol 40 (5) ◽  
pp. 1301-1305 ◽  
Author(s):  
Kimberly R. Powell ◽  
T. Mark McCleskey ◽  
William Tumas ◽  
Joseph M. DeSimone
Keyword(s):  
Carbon Dioxide ◽  
Dense Phase ◽  
Multiple Ligand

Maximum Common Binding Modes (MCBM):  Consensus Docking Scoring Using Multiple Ligand Information and Interaction Fingerprints

2008 ◽  
Vol 48 (2) ◽  
pp. 319-332 ◽  
Author(s):  
Steffen Renner ◽  
Swetlana Derksen ◽  
Sebastian Radestock ◽  
Fabian Mörchen
Keyword(s):  
Binding Modes ◽  
Multiple Ligand ◽  
Interaction Fingerprints

Synthesis of labeled metallocenes via double Π-ligand transfer

1977 ◽  
Vol 13 (4) ◽  
pp. 491-508 ◽  
Author(s):  
E. A. Stadlbauer ◽  
E. Nipper ◽  
M. Wenzel
Keyword(s):  
Ligand Transfer
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