Plastic membrane electrode for selective determination of diclofenac (voltaren) in pharmaceutical preparations

The Analyst ◽  
1994 ◽  
Vol 119 (9) ◽  
pp. 1993 ◽  
Author(s):  
Saad S. M. Hassan ◽  
Ragab M. Abdel-Aziz ◽  
Mohamed S. Abdel-Samad
Keyword(s):  
Pharmaceutical Preparations ◽  
Membrane Electrode ◽  
Selective Determination ◽  
Plastic Membrane

Novel palladium(II) selective membrane electrode based on 4-[(5-mercapto-1,3,4-thiadiazol-2-ylimino)methyl]benzene-1,3-diol

2010 ◽  
Vol 75 (5) ◽  
pp. 563-575 ◽  
Author(s):  
Moslem Mohammadi ◽  
Mehdi Khodadadian ◽  
Mohammad K. Rofouei
Keyword(s):  
Limit Of Detection ◽  
Membrane Electrode ◽  
Aqueous Samples ◽  
Selective Determination ◽  
Poly Vinyl Chloride ◽  
Selective Membrane ◽  
Ph Range ◽  
Palladium Content ◽  
Methyl Benzene

A plasticized poly(vinyl chloride) membrane electrode based on 4-[(5-mercapto-1,3,4-thiadiazol-2-ylimino)methyl]benzene-1,3-diol (L) for highly selective determination of palladium(II) (in PdCl42– form) is developed. The electrode showed a good Nernstian response (29.6 ± 0.4 mV per decade) over a wide concentration range (3.1 × 10–7 to 1.0 × 10–2 mol l–1). The limit of detection was 1.5 × 10–7 mol l–1. The electrode has a response time of about 20 s, and it can be used for at least 2 months without observing any considerable deviation from Nernstian response. The proposed electrode could be used in the pH range of 2.5–5.5. The practical utility of the electrode has been demonstrated by its use for the estimation of palladium content in aqueous samples.

scholarly journals Membrane Sensors for the Selective Determination of Donepezil Hydrochloride

2010 ◽  
Vol 93 (2) ◽  
pp. 549-555 ◽  
Author(s):  
Gamal Abdel Hafiz Mostafa ◽  
Mohamed Hefnawy ◽  
Abdulrahman Al-Majed
Keyword(s):  
Direct Determination ◽  
Pharmaceutical Preparations ◽  
Ion Association ◽  
Phosphomolybdic Acid ◽  
Hplc Method ◽  
Pvc Membrane ◽  
Selective Determination ◽  
Response Characteristics ◽  
Sodium Tetraphenyl Borate

Abstract The construction and electrochemical response characteristics of polyvinylchloride (PVC) membrane sensors for donepezil HCl (DP) are described. The sensing membranes incorporated ion-association complexes of DP cation and sodium tetraphenyl borate (sensor 1), phosphomolybdic acid (sensor 2), or phosphotungstic acid (sensor 3) as electroactive materials. The sensors displayed a fast, stable, and near-Nernstian response over a relatively wide DP concentration range (1 102 to 1 106 M), with cationic slopes of 53.0, 54.0, and 51.0 mV/ concentration decade over a pH range of 4.0 to 8.0. The sensors showed good discrimination of DP from several inorganic and organic compounds. The direct determination of 2.54000.0 g/mL DP showed average recoveries of 99.0, 99.5, and 98.5, and mean RSDs of 1.6, 1.5, and 1.7 at 100.0 g/mL for sensors 1, 2, and 3, respectively. The proposed sensors have been applied for direct determination of DP in two pharmaceutical preparations. The results obtained for determination of DP in tablets using the proposed sensors compared favorably with those obtained using an HPLC method. The sensors have been used as indicator electrodes for potentiometric titration of DP.

scholarly journals A Simple and Efficient Molecularly Imprinted Electrochemical Sensor for the Selective Determination of Tryptophan

Biomolecules ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 294 ◽  
Author(s):  
Tian ◽  
Deng ◽  
Wu ◽  
Ding ◽  
Li ◽  
...  
Keyword(s):  
Crosslinking Agent ◽  
Pharmaceutical Preparations ◽  
Chitosan Film ◽  
Template Molecule ◽  
Serum Samples ◽  
Solution Ph ◽  
Molecularly Imprinted ◽  
Functional Polymer ◽  
Selective Determination

In this paper, a tryptophan (Trp) molecularly imprinted chitosan film was prepared on the surface of an acetylene black paste electrode using chitosan as the functional polymer, Trp as the template molecule and sulfuric acid as the crosslinking agent. The surface morphologies of non-imprinted and imprinted electrodes were characterized by scanning electron microscopy (SEM). The formation of hydrogen bonds between the functional polymer and the template molecule was confirmed by infrared spectroscopy. Some factors affecting the performance of the imprinted electrode such as the concentration of chitosan, the mass ratio of chitosan to Trp, the dropping amount of the chitosan-Trp mixture, the solution pH, and the accumulation potential and time were discussed. The experimental results show that the imprinted electrode exhibit good affinity and selectivity for Trp. The dynamic linear ranges of 0.01–4 M, 4–20 M and 20–100 M were obtained by second derivative linear sweep voltammetry, and the detection limit was calculated to be 8.0 nM. The use of the imprinted electrode provides an effective method for eliminating the interference of potentially interfering substances. In addition, the sensor has high sensitivity, reproducibility and stability, and can be used for the determination of Trp in pharmaceutical preparations and human serum samples.

Liquid membrane electrode for selective determination of thiocyanate

The Analyst ◽  
1987 ◽  
Vol 112 (12) ◽  
pp. 1709 ◽  
Author(s):  
Saad S. M. Hassan ◽  
M. A. M. F. Elmosalamy
Keyword(s):  
Liquid Membrane ◽  
Membrane Electrode ◽  
Selective Determination ◽  
Liquid Membrane Electrode
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