Simultaneous determination of phenobarbitone, primidone and phenytoin in small samples of blood by gas-liquid chromatography

The Analyst ◽  
1977 ◽  
Vol 102 (1210) ◽  
pp. 35 ◽  
Author(s):  
A. M. Bruce ◽  
Hamilton Smith
1992 ◽  
Author(s):  
Ronald L. Shippee ◽  
Avery A. Johnson ◽  
William G. Cioffi ◽  
James Lasko ◽  
Thomas E. LeVoyer

1971 ◽  
Vol 17 (7) ◽  
pp. 607-609 ◽  
Author(s):  
H E Booker ◽  
B Darcey

Abstract A simple gas chromatographic procedure is described for the measurement of trimethadione and its major metabolite, dimethadione, in serum. The method, with which compounds can be determined on a single extraction and injection, is reliable and free from interference caused by other drugs, particularly those that the patient is likely to be taking in combination with trimethadione.


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