Innovations in Biomolecular Modeling and Simulations

2012 ◽  
Keyword(s):  
Modeling And Simulations ◽  
Biomolecular Modeling

Memory Processes, Aging, Cognitive Decline, and Neurodegenerative Diseases

2006 ◽  
Vol 11 (4) ◽  
pp. 304-311 ◽  
Author(s):  
Lars-Göran Nilsson
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Decline ◽  
Neurodegenerative Disease ◽  
Genetic Markers ◽  
Brain Activity ◽  
Memory Performance ◽  
Modeling And Simulations ◽  
Aging And Health ◽  
Explained Variance ◽  
Different Levels

This paper presents four domains of markers that have been found to predict later cognitive impairment and neurodegenerative disease. These four domains are (1) data patterns of memory performance, (2) cardiovascular factors, (3) genetic markers, and (4) brain activity. The critical features of each domain are illustrated with data from the longitudinal Betula Study on memory, aging, and health ( Nilsson et al., 1997 ; Nilsson et al., 2004 ). Up to now, early signs regarding these domains have been examined one by one and it has been found that they are associated with later cognitive impairment and neurodegenerative disease. However, it was also found that each marker accounts for only a very small part of the total variance, implying that single markers should not be used as predictors for cognitive decline or neurodegenerative disease. It is discussed whether modeling and simulations should be used as tools to combine markers at different levels to increase the amount of explained variance.

Improved Environment Support for Modeling and Simulations

2001 ◽  
Author(s):  
Alan F. Blumberg ◽  
Nicholas B. Kim
Keyword(s):  
Modeling And Simulations

scholarly journals Additive Manufacturing for Effective Smart Structures: The Idea of 6D Printing

2021 ◽  
Vol 5 (5) ◽  
pp. 119
Author(s):  
Stelios K. Georgantzinos ◽  
Georgios I. Giannopoulos ◽  
Panteleimon A. Bakalis
Keyword(s):  
Additive Manufacturing ◽  
Degrees Of Freedom ◽  
Smart Structures ◽  
Interaction Mechanism ◽  
Modeling And Simulations ◽  
Environmental Stimulus ◽  
Material Component ◽  
Design And Manufacturing ◽  
First Time ◽  
Printing Techniques

This paper aims to establish six-dimensional (6D) printing as a new branch of additive manufacturing investigating its benefits, advantages as well as possible limitations concerning the design and manufacturing of effective smart structures. The concept of 6D printing, to the authors’ best knowledge, is introduced for the first time. The new method combines the four-dimensional (4D) and five-dimensional (5D) printing techniques. This means that the printing process is going to use five degrees of freedom for creating the final object while the final produced material component will be a smart/intelligent one (i.e., will be capable of changing its shape or properties due to its interaction with an environmental stimulus). A 6D printed structure can be stronger and more effective than a corresponding 4D printed structure, can be manufactured using less material, can perform movements by being exposed to an external stimulus through an interaction mechanism, and it may learn how to reconfigure itself suitably, based on predictions via mathematical modeling and simulations.

RANS Modeling and Simulations of Synthetic Jets

2004 ◽  
Author(s):  
Gianluca Iaccarino ◽  
Claudio Marongiu ◽  
Pietro Catalano ◽  
Marcello Amato
Keyword(s):  
Synthetic Jets ◽  
Modeling And Simulations ◽  
Rans Modeling
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