Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I

Gui-Lin Chen; Yong-Qiang Tian; Jian-Lin Wu; Na Li; Ming-Quan Guo

doi:10.1038/srep38284

Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I

Scientific Reports ◽

10.1038/srep38284 ◽

2016 ◽

Vol 6 (1) ◽

Cited By ~ 20

Author(s):

Gui-Lin Chen ◽

Yong-Qiang Tian ◽

Jian-Lin Wu ◽

Na Li ◽

Ming-Quan Guo

Keyword(s):

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Amaryllidaceae Alkaloids ◽

Lycoris Radiata ◽

Antiproliferative Activities

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Faculty Opinions recommendation of Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717993387.793473725 ◽

2013 ◽

Author(s):

William Holloman ◽

Jeanette Sutherland

Keyword(s):

Topoisomerase I ◽

Dna Topoisomerase I ◽

Replication Forks ◽

Dna Topoisomerase

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Temporal and Spatial Dynamics of DNA Topoisomerase I in Prostate Cancer

10.21236/ada433934 ◽

2005 ◽

Author(s):

Randy M. Wadkins

Keyword(s):

Prostate Cancer ◽

Topoisomerase I ◽

Spatial Dynamics ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Temporal And Spatial

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Mode of inhibition of eukaryotic DNA topoisomerase I inhibitors.

Nippon Nōgeikagaku Kaishi ◽

10.1271/nogeikagaku1924.65.1008 ◽

1991 ◽

Vol 65 (6) ◽

pp. 1008-1010

Author(s):

Hiro-omi TAMURA ◽

Yoji IKEGAMI

Keyword(s):

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Topoisomerase I Inhibitors ◽

Eukaryotic Dna

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Interaction between DNA and Escherichia coli DNA topoisomerase I. Formation of complexes between the protein and superhelical and nonsuperhelical duplex DNAs.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)86633-4 ◽

1979 ◽

Vol 254 (21) ◽

pp. 11082-11088

Author(s):

L.F. Liu ◽

J.C. Wang

Keyword(s):

Escherichia Coli ◽

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Formation Of Complexes

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DNA topoisomerase I phosphorylation in murine fibroblasts treated with 12-O-tetradecanoylphorbol-13-acetate and in vitro by protein kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)49889-x ◽

1992 ◽

Vol 267 (16) ◽

pp. 11156-11162

Author(s):

D.S. Samuels ◽

N Shimizu

Keyword(s):

Protein Kinase ◽

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Murine Fibroblasts

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Increased synthesis and degradation of DNA topoisomerase I during the initial phase of human T lymphocyte proliferation.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)46723-8 ◽

1993 ◽

Vol 268 (25) ◽

pp. 18982-18986

Author(s):

C.L. Hwong ◽

C.Y. Chen ◽

H.F. Shang ◽

J. Hwang

Keyword(s):

T Lymphocyte ◽

Lymphocyte Proliferation ◽

Initial Phase ◽

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

T Lymphocyte Proliferation ◽

Human T Lymphocyte ◽

Synthesis And Degradation

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Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)41531-1 ◽

1993 ◽

Vol 268 (30) ◽

pp. 22322-22330

Author(s):

A.M. Knab ◽

J Fertala ◽

M.A. Bjornsti

Keyword(s):

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase

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An engineered mutant of vaccinia virus DNA topoisomerase I is sensitive to the anti-cancer drug camptothecin.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)35746-6 ◽

1992 ◽

Vol 267 (34) ◽

pp. 24177-24180

Author(s):

M Gupta ◽

C.X. Zhu ◽

Y.C. Tse-Dinh

Keyword(s):

Vaccinia Virus ◽

Topoisomerase I ◽

Cancer Drug ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Anti Cancer

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The histone H3/H4.N1 complex supplemented with histone H2A-H2B dimers and DNA topoisomerase I forms nucleosomes on circular DNA under physiological conditions.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)77329-8 ◽

1990 ◽

Vol 265 (24) ◽

pp. 14487-14496 ◽

Cited By ~ 2

Author(s):

K. Zucker ◽

A. Worcel

Keyword(s):

Topoisomerase I ◽

Histone H3 ◽

Dna Topoisomerase I ◽

Histone H2a ◽

Dna Topoisomerase ◽

Circular Dna ◽

Physiological Conditions

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beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)41552-9 ◽

1993 ◽

Vol 268 (30) ◽

pp. 22463-22468 ◽

Cited By ~ 2

Author(s):

C.J. Li ◽

L Averboukh ◽

A.B. Pardee

Keyword(s):

Mode Of Action ◽

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Topoisomerase I Inhibitor

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