scholarly journals Double-Network Hydrogel with Tunable Mechanical Performance and Biocompatibility for the Fabrication of Stem Cells-Encapsulated Fibers and 3D Assemble

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Zhe Liang ◽  
Chenguang Liu ◽  
Lili Li ◽  
Peidi Xu ◽  
Guoan Luo ◽  
...  
Author(s):  
Jun Suzuka ◽  
Masumi Tsuda ◽  
Lei Wang ◽  
Shinji Kohsaka ◽  
Karin Kishida ◽  
...  

2020 ◽  
Vol 107 ◽  
pp. 110333 ◽  
Author(s):  
Wenqiang Li ◽  
Dongwei Wu ◽  
Duo Hu ◽  
Shanshan Zhu ◽  
Cile Pan ◽  
...  

Materials ◽  
2019 ◽  
Vol 12 (20) ◽  
pp. 3333 ◽  
Author(s):  
Niu ◽  
Zhang ◽  
Shen ◽  
Sheng ◽  
Fu ◽  
...  

A new design strategy was proposed to improve the mechanical performance of double network (DN) hydrogels by introducing polyhydroxy compounds into the DN structure and form a physically linked double network through the interaction of hydrogen bonding. Herein, agar/poly(acrylic acid)/hydroxyethyl cellulose composite hydrogels could be prepared by a simple one-pot method. The resulting hydrogels exhibit highly mechanical properties and excellent recoverability, which have potential applications in biomedical fields.


Materials ◽  
2020 ◽  
Vol 13 (7) ◽  
pp. 1763
Author(s):  
Leto-Aikaterini Tziveleka ◽  
Andreas Sapalidis ◽  
Stefanos Kikionis ◽  
Eleni Aggelidou ◽  
Efterpi Demiri ◽  
...  

Ulvan, a bioactive natural sulfated polysaccharide, and gelatin, a collagen-derived biopolymer, have attracted interest for the preparation of biomaterials for different biomedical applications, due to their demonstrated compatibility for cell attachment and proliferation. Both ulvan and gelatin have exhibited osteoinductive potential, either alone or in combination with other materials. In the current work, a series of novel hybrid scaffolds based on crosslinked ulvan and gelatin was designed, prepared and characterized. Their mechanical performance, thermal stability, porosity, water-uptake and in vitro degradation ability were assessed, while their morphology was analyzed through scanning electron microscopy. The prepared hybrid ulvan/gelatin scaffolds were characterized by a highly porous and interconnected structure. Human adipose-derived mesenchymal stem cells (hADMSCs) were seeded in selected ulvan/gelatin hybrid scaffolds and their adhesion, survival, proliferation, and osteogenic differentiation efficiency was evaluated. Overall, it was found that the prepared hybrid sponge-like scaffolds could efficiently support mesenchymal stem cells’ adhesion and proliferation, suggesting that such scaffolds could have potential uses in bone tissue engineering.


2019 ◽  
Vol 181 ◽  
pp. 879-889 ◽  
Author(s):  
Joo Hee Choi ◽  
Ok Kyun Choi ◽  
Jeonghun Lee ◽  
Joungyoun Noh ◽  
Sumi Lee ◽  
...  

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