scholarly journals Time-Course Gene Expression Profiling Reveals a Novel Role of Non-Canonical WNT Signaling During Neural Induction

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Cindy Tzu-Ling Huang ◽  
Yunlong Tao ◽  
Jianfeng Lu ◽  
Jeffrey R. Jones ◽  
Lucas Fowler ◽  
...  
Keyword(s):  
Gene Expression ◽  
Wnt Signaling ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Time Course ◽  
Neural Induction ◽  
Canonical Wnt Signaling ◽  
Canonical Wnt

scholarly journals The Role of Canonical Wnt Signaling in Regulating Radioresistance

2018 ◽  
Vol 48 (2) ◽  
pp. 419-432 ◽  
Author(s):  
Yuanyuan Zhao ◽  
Leilei Tao ◽  
Jun Yi ◽  
Haizhu Song ◽  
Longbang Chen
Keyword(s):  
Wnt Signaling ◽  
Cancer Progression ◽  
Wnt Signaling Pathway ◽  
Growth Factor Receptor ◽  
Cancer Resistance ◽  
Canonical Wnt Signaling ◽  
Damage Repair ◽  
Epidermal Growth ◽  
Canonical Wnt

Radioresistance is a major obstacle in radiotherapy for cancer, and strategies are needed to overcome this problem. Currently, radiotherapy combined with targeted therapy such as inhibitors of phosphoinosotide 3-kinase/Akt and epidermal growth factor receptor signaling have become the focus of studies on radiosensitization. Apart from these two signaling pathways, which promote radioresistance, deregulation of Wnt signaling is also associated with the radioresistance of multiple cancers. Wnts, as important messengers in the tumor microenvironment, are involved in cancer progression mainly via canonical Wnt signaling. Their role in promoting DNA damage repair and inhibiting apoptosis facilitates cancer resistance to radiation. Thus, it seems reasonable to target Wnt signaling as a method for overcoming radioresistance. Many small-molecule inhibitors that target the Wnt signaling pathway have been identified and shown to promote radiosensitization. Therefore, a Wnt signaling inhibitor may help to overcome radioresistance in cancer therapy.

scholarly journals Chromatin-associated APC regulates gene expression in collaboration with canonical WNT signaling and AP-1

Oncotarget ◽  
2018 ◽  
Vol 9 (58) ◽  
pp. 31214-31230 ◽  
Author(s):  
William Hankey ◽  
Zhong Chen ◽  
Maxwell J. Bergman ◽  
Max O. Fernandez ◽  
Baris Hancioglu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Wnt Signaling ◽  
Canonical Wnt Signaling ◽  
Canonical Wnt

Gene expression profiling defines the role of ATP-exposed keratinocytes in skin inflammation

2010 ◽  
Vol 58 (2) ◽  
pp. 143-151 ◽  
Author(s):  
Hiroshi Ohara ◽  
Rumiko Saito ◽  
Satoshi Hirakawa ◽  
Miki Shimada ◽  
Nariyasu Mano ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Skin Inflammation

The role of magnesium ions in bone regeneration involves the canonical Wnt signaling pathway

2019 ◽  
Vol 98 ◽  
pp. 246-255 ◽  
Author(s):  
Chu-Chih Hung ◽  
Amy Chaya ◽  
Kai Liu ◽  
Konstantinos Verdelis ◽  
Charles Sfeir
Keyword(s):  
Wnt Signaling ◽  
Bone Regeneration ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Magnesium Ions ◽  
Canonical Wnt Signaling ◽  
Canonical Wnt

scholarly journals Role of Arabidopsis CHL27 Protein for Photosynthesis, Chloroplast Development and Gene Expression Profiling

2008 ◽  
Vol 49 (9) ◽  
pp. 1350-1363 ◽  
Author(s):  
Woo Young Bang ◽  
In Sil Jeong ◽  
Dae Won Kim ◽  
Chak Han Im ◽  
Chen Ji ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Chloroplast Development
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