scholarly journals Histological response of soda-lime glass-ceramic bactericidal rods implanted in the jaws of beagle dogs

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
José S. Moya ◽  
Arturo Martínez ◽  
Roberto López-Píriz ◽  
Francisco Guitián ◽  
Luis A. Díaz ◽  
...  

Abstract Bacterial and fungal infections remain a major clinical challenge. Implant infections very often require complicated revision procedures that are troublesome to patients and costly to the healthcare system. Innovative approaches to tackle infections are urgently needed. We investigated the histological response of novel free P2O5 glass-ceramic rods implanted in the jaws of beagle dogs. Due to the particular percolated morphology of this glass-ceramic, the dissolution of the rods in the animal body environment and the immature bone formation during the fourth months of implantation maintained the integrity of the glass-ceramic rod. No clinical signs of inflammation took place in any of the beagle dogs during the four months of implantation. This new glass-ceramic biomaterial with inherent bactericidal and fungicidal properties can be considered as an appealing candidate for bone tissue engineering.

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
José S. Moya ◽  
Arturo Martínez ◽  
Roberto López-Píriz ◽  
Francisco Guitián ◽  
Luis A. Díaz ◽  
...  

2020 ◽  
Vol 10 (16) ◽  
pp. 5714
Author(s):  
Miroslava Hujova ◽  
Patricia Rabelo Monich ◽  
Jaroslav Sedlacek ◽  
Miroslav Hnatko ◽  
Jozef Kraxner ◽  
...  

Both vitrified bottom ashes (VBAs) and waste glasses are forms of inorganic waste material that are widely landfilled, despite having some economic potential. Building on previous studies, we prepared glass-ceramic foams by the combination of VBA with either soda-lime glass (SLG) or borosilicate glass (BSG). Suspensions of fine powders in weakly alkaline solution underwent gelation, followed by frothing at nearly room temperature. Hardened “green” foams were sintered, with concurrent crystallization, at 850–1000 °C. All foams were highly porous (>70%), with mostly open porosity. The glass addition was fundamental in both gelation (promoting the formation of carbonate and silicate hydrated phases) and firing steps. While SLG addition enhanced the viscous flow sintering, without a significant impact on the crystallization of gehlenite, the main crystalline phase from the devitrification of VBA, BSG addition caused a reactive sintering, with remarkable changes in the phase assemblage. The glass addition generally also allowed lower sintering temperatures and yielded products with excellent crushing strength. However, only specific conditions resulted in the complete immobilization of pollutants (e.g., Cr3+ ions).


Author(s):  
S. López-Esteban ◽  
J.F. Bartolomé ◽  
L.A. Dí;az ◽  
L. Esteban-Tejeda ◽  
C. Prado ◽  
...  

Author(s):  
Branimir Bajac ◽  
Jovana Stanojev ◽  
Slobodan Birgermajer ◽  
Milena Radojevic ◽  
Jovan Matovic

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 129
Author(s):  
Marcos Soldera ◽  
Sabri Alamri ◽  
Paul Alexander Sürmann ◽  
Tim Kunze ◽  
Andrés Fabián Lasagni

All-purpose glasses are common in many established and emerging industries, such as microelectronics, photovoltaics, optical components, and biomedical devices due to their outstanding combination of mechanical, optical, thermal, and chemical properties. Surface functionalization through nano/micropatterning can further enhance glasses’ surface properties, expanding their applicability into new fields. Although laser structuring methods have been successfully employed on many absorbing materials, the processability of transparent materials with visible laser radiation has not been intensively studied, especially for producing structures smaller than 10 µm. Here, interference-based optical setups are used to directly pattern soda lime substrates through non-lineal absorption with ps-pulsed laser radiation in the visible spectrum. Line- and dot-like patterns are fabricated with spatial periods between 2.3 and 9.0 µm and aspect ratios up to 0.29. Furthermore, laser-induced periodic surface structures (LIPSS) with a feature size of approximately 300 nm are visible within these microstructures. The textured surfaces show significantly modified properties. Namely, the treated surfaces have an increased hydrophilic behavior, even reaching a super-hydrophilic state for some cases. In addition, the micropatterns act as relief diffraction gratings, which split incident light into diffraction modes. The process parameters were optimized to produce high-quality textures with super-hydrophilic properties and diffraction efficiencies above 30%.


Crystals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 488
Author(s):  
Oumaima Nasry ◽  
Abderrahim Samaouali ◽  
Sara Belarouf ◽  
Abdelkrim Moufakkir ◽  
Hanane Sghiouri El Idrissi ◽  
...  

This study aims to provide a thermophysical characterization of a new economical and green mortar. This material is characterized by partially replacing the cement with recycled soda lime glass. The cement was partially substituted (10, 20, 30, 40, 50 and 60% in weight) by glass powder with a water/cement ratio of 0.4. The glass powder and four of the seven samples were analyzed using a scanning electron microscope (SEM). The thermophysical properties, such as thermal conductivity and volumetric specific heat, were experimentally measured in both dry and wet (water saturated) states. These properties were determined as a function of the glass powder percentage by using a CT-Meter at different temperatures (20 °C, 30 °C, 40 °C and 50 °C) in a temperature-controlled box. The results show that the thermophysical parameters decreased linearly when 60% glass powder was added to cement mortar: 37% for thermal conductivity, 18% for volumetric specific heat and 22% for thermal diffusivity. The density of the mortar also decreased by about 11% in dry state and 5% in wet state. The use of waste glass powder as a cement replacement affects the thermophysical properties of cement mortar due to its porosity as compared with the control mortar. The results indicate that thermal conductivity and volumetric specific heat increases with temperature increase and/or the substitution rate decrease. Therefore, the addition of waste glass powder can significantly affect the thermophysical properties of ordinary cement mortar.


2020 ◽  
Author(s):  
Iskender Akkurt ◽  
Kadir Gunoglu ◽  
Recep Kurtuluş ◽  
Taner Kavas

Heritage ◽  
2021 ◽  
Vol 4 (1) ◽  
pp. 524-540
Author(s):  
Philippe Colomban ◽  
Gulsu Simsek Franci ◽  
Farahnaz Koleini

In the late 19th century, ancient tombs were discovered near the village of Vohemar at the northeastern point of Madagascar, and subsequent excavations during the French period (1896–1945) revealed the presence of a major necropolis active from ~13th to 18th centuries. Some artefacts (Chinese ceramic shards and glass trade beads) recovered from these excavations was sent to France and now in part belong to the collection of the Musée d’Histoire Naturelle, Nimes. Carnelian and glass trade beads were analyzed with a mobile Raman spectrometer, which identified different materials (soda-lime glass, quartz/moganite, carnelian/citrine, chalcedony) and coloring agents (Naples yellow, cassiterite, amber chromophore, transition metal ions, etc.). The results are compared with those obtained on beads excavated at different sites of Southern Africa and at Mayotte Island, and it appears that (most of) the beads come from southern Asia and Europe. The results confirmed the role that northern Madagascar played within the maritime networks of the Western Indian Ocean during the 15th–16th century.


2021 ◽  
Vol 10 (Supplement_1) ◽  
pp. S19-S19
Author(s):  
Valentina Gutiérrez ◽  
Ximena Claverie

Abstract Background Fever during neutropenia is a common occurrence in children with cancer. In a systematic review of RCTs of pediatric febrile neutropenia, compared monotherapy with aminoglycoside-containing combination therapy found no significant differences in failure rates, infection-related mortality, or overall mortality. The updated pediatric-specific guidelines recommend initiation of empirical antibiotic monotherapy using an antipseudomonal β-lactam, a fourth-generation cephalosporin, or a carbapenem for pediatric high-risk febrile neutropenia. However, local epidemiology and resistance patterns should be evaluated regularly. Our local hospital epidemiology does not have Pseudomonas aeruginosa isolates, therefore, we used ceftriaxone as monotherapy in patients with high-risk febrile neutropenia without other risk factors. The goal of our investigation is to describe the experience of using third-generation cephalosporins in these patients. Methods Descriptive study of high-risk febrile neutropenia episodes in patients admitted to the Pediatric Oncology Unit of Hospital Dr. Sótero del Río, Santiago, Chile. We included patients ≤15 years from June 2016 until November 2019. Results We found a total of 133 high-risk febrile neutropenia episodes corresponding to 50 patients, 78% were leukemia and 22% were solid tumor patients. Of the 133 episodes, 92 (69%) had clinical signs at admission, mostly respiratory in 46 (50%) of the cases, 18 (29%) had mucositis and 13 (14%) had diarrhea. Of 133 episodes, 41 (31%) did not have any source at clinical examination. Eighty-six (65%) cases started ceftriaxone at admission, 28 (33%) maintained ceftriaxone for 7 days of treatment with good clinical response. Of this group 58 (67%) patients changed treatment: 32 (37%) cases started second-line antibiotics for clinical worsening, 19 (22%) cases required second- and third-line antibiotics for persistent fever and clinical worsening, and 7 (8%) received third-line antibiotics from the start for past microbiological history. Sixteen (12%) cases of total evolved with sepsis requiring intensive care unit management. We had 30 (23%) episodes with positive blood culture, 11 (37%) due to gram-positive bacteria, 16 (53%) gram-negative bacteria, and 3 (10%) cases of fungal infections. Of the gram-negative bacteria, 7 (44%) were ESBL producers, without P. aeruginosa isolates. One case died (0.7%) for refractory sepsis due to gram-negative bacteria. Conclusion Although we did not have P. aeruginosa isolates, due to the spread of ESBL strains, monotherapy with ceftriaxone is not a good option as initial therapy for high-risk febrile neutropenia patients. The empiric therapy has to be evaluated regularly and should always be based on local epidemiology.


Sign in / Sign up

Export Citation Format

Share Document