scholarly journals Identification of a residue crucial for the angiostatic activity of human mini tryptophanyl-tRNA synthetase by focusing on its molecular evolution

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Terumasa Nakamoto ◽  
Miki Miyanokoshi ◽  
Tomoaki Tanaka ◽  
Keisuke Wakasugi
Keyword(s):  
Molecular Evolution ◽  
Trna Synthetase ◽  
Angiostatic Activity

scholarly journals Structural Basis for the Molecular Evolution of Glutamyl-tRNA Synthetase.

1997 ◽  
Vol 37 (1) ◽  
pp. 321-325
Author(s):  
Osamu NUREKI ◽  
Shigeyuki YOKOYAMA
Keyword(s):  
Molecular Evolution ◽  
Trna Synthetase ◽  
Structural Basis

scholarly journals Erratum to: Molecular Evolution of Aminoacyl tRNA Synthetase Proteins in the Early History of Life

2012 ◽  
Vol 42 (4) ◽  
pp. 377-377
Author(s):  
Gregory P. Fournier ◽  
Cheryl P. Andam ◽  
Eric J. Alm ◽  
J. Peter Gogarten
Keyword(s):  
Molecular Evolution ◽  
Trna Synthetase ◽  
Early History ◽  
Aminoacyl Trna Synthetase ◽  
History Of

scholarly journals Molecular Evolution of Aminoacyl tRNA Synthetase Proteins in the Early History of Life

2011 ◽  
Vol 41 (6) ◽  
pp. 621-632 ◽  
Author(s):  
Gregory P. Fournier ◽  
Cheryl P. Andam ◽  
Eric J. Alm ◽  
J. Peter Gogarten
Keyword(s):  
Molecular Evolution ◽  
Trna Synthetase ◽  
Early History ◽  
Aminoacyl Trna Synthetase ◽  
History Of

A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase

2004 ◽  
Vol 11 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Yoshiaki Kise ◽  
Sang Won Lee ◽  
Sang Gyu Park ◽  
Shuya Fukai ◽  
Toru Sengoku ◽  
...  
Keyword(s):  
Trna Synthetase ◽  
Short Peptide ◽  
Angiostatic Activity ◽  
Peptide Insertion

Molecular evolution of a cytochrome P450 for the synthesis of potential antidepressant (2R,6R)-hydroxynorketamine

2021 ◽  
Author(s):  
Ansgar Bokel ◽  
Michael C. Hutter ◽  
Vlada B. Urlacher
Keyword(s):  
Cytochrome P450 ◽  
Molecular Evolution ◽  
Cytochrome P450 Monooxygenase ◽  
P450 Monooxygenase ◽  
Effective Synthesis

Engineered cytochrome P450 monooxygenase CYP154E1 enables the effective synthesis of the potential antidepressant (2R,6R)-hydroxynorketamine via N-demethylation and regio- and stereoselective hydroxylation of (R)-ketamine.

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