A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase

Yoshiaki Kise; Sang Won Lee; Sang Gyu Park; Shuya Fukai; Toru Sengoku; Ryohei Ishii; Shigeyuki Yokoyama; Sunghoon Kim; Osamu Nureki

doi:10.1038/nsmb722

A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase

Nature Structural & Molecular Biology ◽

10.1038/nsmb722 ◽

2004 ◽

Vol 11 (2) ◽

pp. 149-156 ◽

Cited By ~ 53

Author(s):

Yoshiaki Kise ◽

Sang Won Lee ◽

Sang Gyu Park ◽

Shuya Fukai ◽

Toru Sengoku ◽

...

Keyword(s):

Trna Synthetase ◽

Short Peptide ◽

Angiostatic Activity ◽

Peptide Insertion

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Identification of a residue crucial for the angiostatic activity of human mini tryptophanyl-tRNA synthetase by focusing on its molecular evolution

Scientific Reports ◽

10.1038/srep24750 ◽

2016 ◽

Vol 6 (1) ◽

Cited By ~ 8

Author(s):

Terumasa Nakamoto ◽

Miki Miyanokoshi ◽

Tomoaki Tanaka ◽

Keisuke Wakasugi

Keyword(s):

Molecular Evolution ◽

Trna Synthetase ◽

Angiostatic Activity

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Structural Basis for the Angiostatic Activity of Human Tryptophanyl-tRNA Synthetase

Seibutsu Butsuri ◽

10.2142/biophys.45.314 ◽

2005 ◽

Vol 45 (6) ◽

pp. 314-319

Author(s):

Osamu NUREKI

Keyword(s):

Trna Synthetase ◽

Structural Basis ◽

Angiostatic Activity

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Orphan designation: 505 amino acid protein, corresponding to amino acids 2-506 of the wild-type human histidyl-tRNA synthetase, Treatment of limb-girdle muscular dystrophy

Case Medical Research ◽

10.31525/cmr-2935ce2 ◽

2020 ◽

Author(s):

Keyword(s):

Amino Acids ◽

Amino Acid ◽

Muscular Dystrophy ◽

Trna Synthetase ◽

Limb Girdle Muscular Dystrophy ◽

Wild Type ◽

Orphan Designation ◽

Acid Protein ◽

Amino Acid Protein

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Faculty Opinions recommendation of An aminoacyl tRNA synthetase whose sequence fits into neither of the two known classes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1000088.1101 ◽

2001 ◽

Author(s):

Anne-Catherine Dock-Bregeon

Keyword(s):

Trna Synthetase ◽

Aminoacyl Trna Synthetase

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Faculty Opinions recommendation of A conserved threonine within Escherichia coli leucyl-tRNA synthetase prevents hydrolytic editing of leucyl-tRNALeu.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1000366.1351 ◽

2001 ◽

Author(s):

Anne-Catherine Dock-Bregeon

Keyword(s):

Escherichia Coli ◽

Trna Synthetase

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Faculty Opinions recommendation of Discrimination of tRNA(Leu) isoacceptors by the mutants of Escherichia coli leucyl-tRNA synthetase in editing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1009103.118807 ◽

2002 ◽

Author(s):

Anne-Catherine Dock-Bregeon

Keyword(s):

Escherichia Coli ◽

Trna Synthetase

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Faculty Opinions recommendation of Crystal structure of a human aminoacyl-tRNA synthetase cytokine.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1010763.176313 ◽

2002 ◽

Author(s):

John Perona

Keyword(s):

Crystal Structure ◽

Trna Synthetase ◽

Aminoacyl Trna Synthetase

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Faculty Opinions recommendation of Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1028758.343749 ◽

2005 ◽

Author(s):

Dehua Pei

Keyword(s):

Protein Labeling ◽

Phosphopantetheinyl Transferase ◽

Short Peptide ◽

Peptide Tag

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Faculty Opinions recommendation of An active dominant mutation of glycyl-tRNA synthetase causes neuropathy in a Charcot-Marie-Tooth 2D mouse model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047563.497530 ◽

2006 ◽

Cited By ~ 1

Author(s):

Brian Popko

Keyword(s):

Mouse Model ◽

Trna Synthetase ◽

Dominant Mutation ◽

Charcot Marie Tooth

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Faculty Opinions recommendation of Short peptide induces an "uncultivable" microorganism to grow in vitro.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1115026.570993 ◽

2008 ◽

Author(s):

June Kwon-Chung

Keyword(s):

Short Peptide

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