scholarly journals Central transthyretin acts to decrease food intake and body weight

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Fenping Zheng ◽  
Yonwook J. Kim ◽  
Timothy H. Moran ◽  
Hong Li ◽  
Sheng Bi
2014 ◽  
Vol 11 (1) ◽  
pp. 36 ◽  
Author(s):  
Clare L Adam ◽  
Patricia A Williams ◽  
Matthew J Dalby ◽  
Karen Garden ◽  
Lynn M Thomson ◽  
...  

Author(s):  
Jesse Z. Dong ◽  
Daniel B. DeOliveira ◽  
Heather A. Halem ◽  
John E. Taylor ◽  
Pierre Roubert ◽  
...  

2019 ◽  
Vol 149 (7) ◽  
pp. 1180-1188
Author(s):  
Sandra L Clark ◽  
D Dan Ramdath ◽  
Brittany V King ◽  
Katherine E O'Connor ◽  
Michel Aliani ◽  
...  

ABSTRACT Background Lentils have potential to increase satiety and may contribute to a body weight management strategy; however, the effects on satiety of replacing common food ingredients with lentils within food products remain largely unknown. Objective The aim of this study was to determine the effects of replacing wheat and rice with 2 lentil varieties within muffins and chilies on satiety, test-meal food intake, and 24-h energy intake. Methods Healthy adults consumed muffins or chilies in which wheat or rice was substituted with green (61.8 g) or red (54 g) lentils in 2 randomized crossover studies (muffin study: n = 24, mean ± SE age: 25.4 ± 0.9 y, BMI (in kg/m2): 23.2 ± 0.5; chili study: n = 24, age: 25.7 ± 1.0 y, BMI: 23.2 ± 0.5), with ≥1-wk washout periods between study visits and studies. Subjective appetite sensations measured over 180 min were summarized with total area under the curve (AUC), food intake was measured at an ad libitum test meal, and 24-h energy intake was measured using weighed food records. Treatment effects were compared within each study using repeated-measures ANCOVA (subjective appetite sensations) and ANOVA (food intake, 24-h energy intake). Results Green, but not red, lentil chili significantly increased fullness AUC (17.5%, P = 0.02) and decreased desire to eat AUC (20.1%, P = 0.02) and prospective food consumption AUC (16.7%, P = 0.04) compared with rice chili, with no significant differences between chili treatments for test-meal food intake or 24-h energy intake. Muffin treatments did not significantly differ for any outcomes. Conclusions Replacing rice with green, but not red lentils within chili increases satiety but does not decrease food intake, whereas replacing wheat with lentils within muffins does not increase satiety or decrease food intake in healthy adults. Further study of the role of lentil replacement in food products in body weight management is warranted. This trial was registered at clinicaltrials.gov as NCT03128684.


2014 ◽  
Vol 20 (1) ◽  
pp. 54-60 ◽  
Author(s):  
Matthew R. McFarlane ◽  
Michael S. Brown ◽  
Joseph L. Goldstein ◽  
Tong-Jin Zhao

2018 ◽  
Vol 9 (12) ◽  
pp. 6257-6267 ◽  
Author(s):  
Ting Luo ◽  
Omar Miranda-Garcia ◽  
Geoff Sasaki ◽  
Jinling Wang ◽  
Neil F. Shay

Genistein and daidzein decrease mice food intake, ameliorate symptoms of metabolic syndrome, including decreasing body weight gain, and improving glucose metabolism, and appear to produce differential effects, possibly via the regulation of LXR-mediated pathways.


1973 ◽  
Author(s):  
William W. Beatty ◽  
Thomas R. Vilberg ◽  
Paul B. Revland

2007 ◽  
Vol 2 (S 1) ◽  
Author(s):  
L Plum ◽  
M Matsumoto ◽  
D Accili
Keyword(s):  

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