scholarly journals Endurance training facilitates myoglobin desaturation during muscle contraction in rat skeletal muscle

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Hisashi Takakura ◽  
Yasuro Furuichi ◽  
Tatsuya Yamada ◽  
Thomas Jue ◽  
Minoru Ojino ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Contraction ◽  
Endurance Training ◽  
Rat Skeletal Muscle

scholarly journals Branched-chain α-keto acid dehydrogenase kinase content in rat skeletal muscle is decreased by endurance training

IUBMB Life ◽  
1998 ◽  
Vol 44 (6) ◽  
pp. 1211-1216 ◽  
Author(s):  
Hisao Fujii ◽  
Yoshiharu Shimomura ◽  
Taro Murakami ◽  
Naoya Nakai ◽  
Tasuku Sato ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Endurance Training ◽  
Keto Acid ◽  
Rat Skeletal Muscle ◽  
Acid Dehydrogenase ◽  
Branched Chain

Effects of Endurance Training on Mn-SOD Activity, Content, and mRNA Expression in Rat Skeletal Muscle

1994 ◽  
Vol 87 (s1) ◽  
pp. 84-85
Author(s):  
S Oh-Ishi ◽  
T Kizaki ◽  
H Yamashita ◽  
Y Ohira ◽  
Y Sato ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Mrna Expression ◽  
Endurance Training ◽  
Rat Skeletal Muscle ◽  
Sod Activity

The effects of adenine nucleotide perfusion on interstitial adenosine production in rat skeletal muscle

2018 ◽  
Vol 96 (8) ◽  
pp. 823-829
Author(s):  
Yi Zhao ◽  
Sergio Fabris ◽  
David A. MacLean
Keyword(s):  
Skeletal Muscle ◽  
Muscle Contraction ◽  
Adenine Nucleotide ◽  
Adenine Nucleotides ◽  
Interstitial Space ◽  
Rat Skeletal Muscle ◽  
Adenosine Concentration

The purpose of the present study was to utilize the microdialysis technique in rat skeletal muscle to perfuse varying concentrations of AMP, ADP, and ATP into the interstitium to examine the effects that these adenine nucleotides have on the production of adenosine in the interstitial space. Interstitial adenosine production appears to be related to the type (ATP, ADP, or AMP) and concentration (2–60 μmol/L) of the adenine nucleotide perfused. Interstitial adenosine levels increased (P < 0.05) from baseline (0.18 ± 0.02 and 0.22 ± 0.02 μmol/L) to 0.23 ± 0.02 and 0.41 ± 0.05 μmol/L following 5 and 30 μmol/L AMP perfusion, respectively. Similarly, perfusion with 30 μmol/L ADP and 30, 40, and 60 μmol/L ATP resulted in an increase (P < 0.05) in interstitial adenosine concentration from baseline (0.25 ± 0.02, 0.26 ± 0.02, 0.19 ± 0.03, and 0.14 ± 0.02 μmol/L) to 0.30 ± 0.02, 0.32 ± 0.02, 0.36 ± 0.04, and 0.33 ± 0.04 μmol/L, respectively. Interestingly, the most prominent increase in interstitial adenosine production occurred during the perfusion of 60 μmol/L ATP (126% increase from baseline). These data strongly suggest that interstitial ATP may play a more potent role in stimulating interstitial adenosine production as compared with ADP or AMP. In addition, interstitial adenosine production can occur independent of muscle contraction (voluntary or involuntary) or hypoxia when adequate concentrations of adenine nucleotides are available.

scholarly journals Effects of a Ketogenic Diet Containing Medium-Chain Triglycerides and Endurance Training on Metabolic Enzyme Adaptations in Rat Skeletal Muscle

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1269 ◽  
Author(s):  
Ayumi Fukazawa ◽  
Atsuko Koike ◽  
Takuya Karasawa ◽  
Momoko Tsutsui ◽  
Saki Kondo ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Protein Content ◽  
Endurance Training ◽  
Ketogenic Diet ◽  
Negative Regulator ◽  
Medium Chain Triglycerides ◽  
Rat Skeletal Muscle ◽  
Medium Chain ◽  
Coa Transferase

Long-term intake of a ketogenic diet enhances utilization of ketone bodies, a particularly energy-efficient substrate, during exercise. However, physiological adaptation to an extremely low-carbohydrate diet has been shown to upregulate pyruvate dehydrogenase kinase 4 (PDK4, a negative regulator of glycolytic flux) content in skeletal muscle, resulting in impaired high-intensity exercise capacity. This study aimed to examine the effects of a long-term ketogenic diet containing medium-chain triglycerides (MCTs) on endurance training-induced adaptations in ketolytic and glycolytic enzymes of rat skeletal muscle. Male Sprague-Dawley rats were placed on either a standard diet (CON), a long-chain triglyceride-containing ketogenic diet (LKD), or an MCT-containing ketogenic diet (MKD). Half the rats in each group performed a 2-h swimming exercise, 5 days a week, for 8 weeks. Endurance training significantly increased 3-oxoacid CoA transferase (OXCT, a ketolytic enzyme) protein content in epitrochlearis muscle tissue, and MKD intake additively enhanced endurance training–induced increases in OXCT protein content. LKD consumption substantially increased muscle PDK4 protein level. However, such PDK4 increases were not observed in the MKD-fed rats. In conclusion, long-term intake of ketogenic diets containing MCTs may additively enhance endurance training–induced increases in ketolytic capacity in skeletal muscle without exerting inhibitory effects on carbohydrate metabolism.

scholarly journals Changes in mitochondrial perilipin 3 and perilipin 5 protein content in rat skeletal muscle following endurance training and acute stimulated contraction

2015 ◽  
Vol 100 (4) ◽  
pp. 450-462 ◽  
Author(s):  
S. V. Ramos ◽  
P. C. Turnbull ◽  
R. E. K. MacPherson ◽  
P. J. LeBlanc ◽  
W. E. Ward ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Protein Content ◽  
Endurance Training ◽  
Rat Skeletal Muscle ◽  
Perilipin 5

Na+–K+ pump location and translocation during muscle contraction in rat skeletal muscle

2008 ◽  
Vol 456 (5) ◽  
pp. 979-989 ◽  
Author(s):  
Michael Kristensen ◽  
Martin Krøyer Rasmussen ◽  
Carsten Juel
Keyword(s):  
Skeletal Muscle ◽  
Muscle Contraction ◽  
Rat Skeletal Muscle
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