scholarly journals Perinatal outcomes of maternal overweight and obesity in term infants: a population-based cohort study in Canada

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Angela Elena Vinturache ◽  
Sheila McDonald ◽  
Donna Slater ◽  
Suzanne Tough
Keyword(s):  
Cohort Study ◽  
Perinatal Outcomes ◽  
Population Based ◽  
Overweight And Obesity ◽  
Term Infants ◽  
Maternal Overweight

scholarly journals Maternal Obesity and Risk of Early-onset Neonatal Bacterial Sepsis: Nationwide Cohort and Sibling-controlled Studies

2020 ◽  
Author(s):  
Eduardo Villamor ◽  
Mikael Norman ◽  
Stefan Johansson ◽  
Sven Cnattingius
Keyword(s):  
Early Onset ◽  
Maternal Obesity ◽  
Group B Streptococcus ◽  
Population Based ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
Bacterial Sepsis ◽  
Term Infants ◽  
Cesarean Section Delivery ◽  
Maternal Overweight

Abstract Background Maternal overweight and obesity are related to risks of pregnancy and delivery complications that, in turn, are associated with newborn infections. We examined the associations between early pregnancy body mass index (BMI; kg/m2) and risk of early-onset neonatal bacterial sepsis (EOS). Methods We conducted a nationwide population-based retrospective cohort study of 1 971 346 live singleton infants born in Sweden between 1997 and 2016. Outcome was a culture-confirmed EOS diagnosis. We estimated hazard ratios (HR) of EOS according to BMI using proportional hazard models, and identified potential mediators. Among term infants, we conducted sibling-controlled analyses. Results EOS risk per 1000 live births was 1.48; 0.76 in term and 15.52 in preterm infants. Compared with infants of normal-weight mothers (BMI, 18.5–24.9), the adjusted HR (95% confidence interval [CI]) of EOS for BMI categories <18.5, 25.0–29.9, 30.0–34.9, 35.0–39.9, and ≥40.0 were, respectively, 1.07 (.83–1.40), 1.19 (1.08–1.32), 1.70 (1.49–1.94), 2.11 (1.73–2.58), and 2.50 (1.86–3.38). Maternal overweight and obesity increased the risk of EOS by group B Streptococcus, Staphylococcus aureus, and Escherichia coli. Half of the association was mediated through preeclampsia, cesarean section delivery, and preterm delivery. A dose-response association was consistently apparent in term infants only. In sibling-controlled analyses, every kilogram per meter squared interpregnancy BMI change was associated with a mean 8.3% increase in EOS risk (95% CI, 1.7%–15.3%; P = .01). Conclusions Risk of EOS increases with maternal overweight and obesity severity, particularly in term infants.

scholarly journals Maternal overweight and obesity in early pregnancy and risk of infant mortality: a population based cohort study in Sweden

BMJ ◽  
2014 ◽  
Vol 349 (dec02 6) ◽  
pp. g6572-g6572 ◽  
Author(s):  
S. Johansson ◽  
E. Villamor ◽  
M. Altman ◽  
A.-K. E. Bonamy ◽  
F. Granath ◽  
...  
Keyword(s):  
Cohort Study ◽  
Infant Mortality ◽  
Early Pregnancy ◽  
Population Based ◽  
Overweight And Obesity ◽  
Maternal Overweight

Maternal Overweight and Obesity and Genital Anomalies in Male Offspring: A Population-Based Swedish Cohort Study

2017 ◽  
Vol 31 (4) ◽  
pp. 317-327 ◽  
Author(s):  
Linn Håkonsen Arendt ◽  
Cecilia Høst Ramlau-Hansen ◽  
Morten Søndergaard Lindhard ◽  
Tine Brink Henriksen ◽  
Jørn Olsen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Overweight And Obesity ◽  
Male Offspring ◽  
Maternal Overweight ◽  
Swedish Cohort

scholarly journals Comparison of adverse perinatal outcomes between Asians and Caucasians: a population-based retrospective cohort study in Ontario

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Na Zeng ◽  
Erica Erwin ◽  
Wendy Wen ◽  
Daniel J. Corsi ◽  
Shi Wu Wen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Weight ◽  
Preterm Birth ◽  
Cesarean Section ◽  
Gestational Age ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Perinatal Outcomes ◽  
Population Based ◽  
Adverse Perinatal Outcomes

Abstract Background Racial disparities in adverse perinatal outcomes have been studied in other countries, but little has been done for the Canadian population. In this study, we sought to examine the disparities in adverse perinatal outcomes between Asians and Caucasians in Ontario, Canada. Methods We conducted a population-based retrospective cohort study that included all Asian and Caucasian women who attended a prenatal screening and resulted in a singleton birth in an Ontario hospital (April 1st, 2015-March 31st, 2017). Generalized estimating equation models were used to estimate the independent adjusted relative risks and adjusted risk difference of adverse perinatal outcomes for Asians compared with Caucasians. Results Among 237,293 eligible women, 31% were Asian and 69% were Caucasian. Asians were at an increased risk of gestational diabetes mellitus, placental previa, early preterm birth (< 32 weeks), preterm birth, emergency cesarean section, 3rd and 4th degree perineal tears, low birth weight (< 2500 g, < 1500 g), small-for-gestational-age (<10th percentile, <3rd percentile), neonatal intensive care unit admission, and hyperbilirubinemia requiring treatment, but had lower risks of preeclampsia, macrosomia (birth weight > 4000 g), large-for-gestational-age neonates, 5-min Apgar score < 7, and arterial cord pH ≤7.1, as compared with Caucasians. No difference in risk of elective cesarean section was observed between Asians and Caucasians. Conclusion There are significant differences in several adverse perinatal outcomes between Asians and Caucasians. These differences should be taken into consideration for clinical practices due to the large Asian population in Canada.

Population-based trends and correlates of maternal overweight and obesity, Utah 1991-2001

2005 ◽  
Vol 192 (3) ◽  
pp. 832-839 ◽  
Author(s):  
D. Yvette LaCoursiere ◽  
Lois Bloebaum ◽  
Jeffrey D. Duncan ◽  
Michael W. Varner
Keyword(s):  
Population Based ◽  
Overweight And Obesity ◽  
Maternal Overweight

Admissions and Emergency Visits by Late Preterm Singletons and Twins in the First 5 Years: A Population-Based Cohort Study

2019 ◽  
Author(s):  
Tetsuya Isayama ◽  
Daria O'Reilly ◽  
Joseph Beyene ◽  
Shoo K. Lee ◽  
Prakesh S. Shah ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Infants ◽  
Population Based ◽  
Late Preterm ◽  
Administrative Database ◽  
Term Infants ◽  
Emergency Visits ◽  
Late Preterm Infants ◽  
Adjusted Incidence Rate ◽  
The Difference

Abstract Objective To compare admission and emergency visits of late preterm (340/7–366/7 weeks) versus term infants (370/7–416/7 weeks) in the first 5 years. Study Design This population-based cohort study included all singletons and twins born alive at 340/7 to 416/7 weeks' gestation registered in a health administrative database in Ontario, Canada, between April 1, 2002 and December 31, 2012. Admissions and emergency visits from initial postnatal discharge to 5 years were compared between late preterm and term infants adjusting for maternal and infant characteristics. Results A total of 1,316,931 infants (75,364 late preterm infants) were included. Late preterm infants had more frequent admissions than term infants in the first 5 years in both singletons (adjusted incidence rate ratio [95% confidence interval] = 1.46 [1.42–1.49]) and twins (1.21 [1.11–1.31]). The difference in admissions between late preterm and term infants were smaller in twins than singletons and decreased with children's ages. Twins had less frequent admissions than singletons for late preterm infants, but not for term infants. The emergency visits were more frequent in late preterm than term infants in all the periods. Conclusion Admissions and emergency visits were more frequent in late preterm than term infants through the first 5 years. Admissions were less frequent in late preterm twins than singletons.

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