scholarly journals Long-bone fractures in persons with spinal cord injury

Spinal Cord ◽  
2015 ◽  
Vol 53 (9) ◽  
pp. 701-704 ◽  
Author(s):  
A Frotzler ◽  
B Cheikh-Sarraf ◽  
M Pourtehrani ◽  
J Krebs ◽  
K Lippuner
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Fractures ◽  
Long Bone ◽  
Long Bone Fractures ◽  
Cord Injury

scholarly journals Massive Edema of the Lower Limbs in Patients after Spinal Cord Injury—One Picture, Different Diagnoses

2021 ◽  
Vol 18 (8) ◽  
pp. 4219
Author(s):  
Magdalena Mackiewicz-Milewska ◽  
Małgorzata Cisowska-Adamiak ◽  
Katarzyna Sakwińska ◽  
Iwona Szymkuć-Bukowska ◽  
Iwona Głowacka-Mrotek
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Heterotopic Ossification ◽  
Lower Limb ◽  
Bone Fractures ◽  
Lower Limbs ◽  
University Hospital ◽  
Pain Sensation ◽  
Vein Thrombosis ◽  
Cord Injury

Diagnosis of the cause of massive edema of the lower limbs in patients after spinal cord injury (SCI) can be difficult because of loss of pain sensation, commonly occurring in this group of patients. This paper reviews several different pathologies that can lead to lower-limb edema and the associated diagnostic difficulties. We present four cases of patients with massive edemas of lower limbs at different times after SCI undergoing treatment in the Department of Rehabilitation, University Hospital in Bydgoszcz, Poland. All patients had a lack of pain sensation in the lower limbs and significantly elevated levels of D-dimer. In two cases, deep vein thrombosis (DVT) and intramuscular hematomas (IHs) were diagnosed. IHs were probably a consequence of antithrombotic treatments implemented due to the occurrence of DVT. Heterotopic ossification (HO) was diagnosed in a third case, and, in another patient, who was hospitalized for the longest period after injury, we found humeral bone fractures. Heterotopic ossification, intramuscular haematomas, and bone fractures of the lower limb can mimic DVT. Careful observation of the edema evolution is recommended, as the onset of new symptoms may indicate a different cause of edema from that initially established.

scholarly journals Complex Neuro-Muscular favorable rehabilitation program of a patient with politrauma including spinal cord injury and multiple bone fractures

2018 ◽  
Vol 9 (3) ◽  
pp. 260-263 ◽  
Author(s):  
Cristina Octaviana Daia ◽  
◽  
Sabina Solcan ◽  
Andra Cristina Mihai ◽  
Diana Elena Nita ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Fractures ◽  
Rehabilitation Program ◽  
Cord Injury ◽  
Multiple Bone Fractures

Poster 509 Some Characteristics of Bone Fractures after Spinal Cord Injury

PM&R ◽  
2012 ◽  
Vol 4 ◽  
pp. S364-S365
Author(s):  
Myrlynn Delille ◽  
Kresimir Banovac ◽  
Alberto Martinez-Arizala ◽  
Jasmine Martinez-Barrizonte
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Fractures ◽  
Cord Injury

scholarly journals The Pathophysiology of Osteoporosis after Spinal Cord Injury

2021 ◽  
Vol 22 (6) ◽  
pp. 3057
Author(s):  
Ramsha Shams ◽  
Kelsey P. Drasites ◽  
Vandana Zaman ◽  
Denise Matzelle ◽  
Donald C. Shields ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Treatment Strategies ◽  
Nuclear Factor Κb ◽  
The United States ◽  
Long Bone ◽  
Cellular Mechanisms ◽  
Cellular Protection ◽  
Estrogenic Effects ◽  
Cord Injury

Spinal cord injury (SCI) affects approximately 300,000 people in the United States. Most individuals who sustain severe SCI also develop subsequent osteoporosis. However, beyond immobilization-related lack of long bone loading, multiple mechanisms of SCI-related bone density loss are incompletely understood. Recent findings suggest neuronal impairment and disability may lead to an upregulation of receptor activator of nuclear factor-κB ligand (RANKL), which promotes bone resorption. Disruption of Wnt signaling and dysregulation of RANKL may also contribute to the pathogenesis of SCI-related osteoporosis. Estrogenic effects may protect bones from resorption by decreasing the upregulation of RANKL. This review will discuss the current proposed physiological and cellular mechanisms explaining osteoporosis associated with SCI. In addition, we will discuss emerging pharmacological and physiological treatment strategies, including the promising effects of estrogen on cellular protection.

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