scholarly journals Cognitive and Neurological Outcome of Preterm Infants at the Age of 5-8 Years with Post-Haemorrhagic Ventricular Dilatation Requiring Neurosurgical Intervention

2011 ◽  
Vol 70 ◽  
pp. 306-306
Author(s):  
A J Brouwer ◽  
C Van Stam ◽  
M Uniken Venema ◽  
C Koopman ◽  
F Groenendaal ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Neurological Outcome ◽  
Ventricular Dilatation ◽  
Neurosurgical Intervention

Cognitive and Neurological Outcome at the Age of 5–8 Years of Preterm Infants with Post-Hemorrhagic Ventricular Dilatation Requiring Neurosurgical Intervention

Neonatology ◽  
2012 ◽  
Vol 101 (3) ◽  
pp. 210-216 ◽  
Author(s):  
A.J. Brouwer ◽  
C. van Stam ◽  
M. Uniken Venema ◽  
C. Koopman ◽  
F. Groenendaal ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Neurological Outcome ◽  
Ventricular Dilatation ◽  
Neurosurgical Intervention

scholarly journals Early neurodevelopmental outcome in preterm posthemorrhagic ventricular dilatation and hydrocephalus: Neonatal ICU Network Neurobehavioral Scale and imaging predict 3–6-month motor quotients and Capute Scales

2020 ◽  
Vol 25 (3) ◽  
pp. 217-227 ◽  
Author(s):  
Rebecca A. Dorner ◽  
Marilee C. Allen ◽  
Shenandoah Robinson ◽  
Bruno P. Soares ◽  
Jamie Perin ◽  
...  
Keyword(s):  
Problem Solving ◽  
Preterm Infants ◽  
Ventricular Dilatation ◽  
Imaging Features ◽  
Early Language ◽  
Posthemorrhagic Hydrocephalus ◽  
Neurodevelopmental Disability ◽  
Cystic Changes ◽  
Neonatal Icu ◽  
Neurosurgical Intervention

OBJECTIVEBrain injury remains a serious complication of prematurity. Almost half of infants with severe intraventricular hemorrhage (IVH) develop posthemorrhagic ventricular dilatation (PHVD) and 20% need surgery for posthemorrhagic hydrocephalus (PHH). This population is associated with an increased risk of later neurodevelopmental disability, but there is uncertainty about which radiological and examination features predict later disability. In this study the authors sought to devise and describe a novel combination of neurobehavioral examination and imaging for prediction of neurodevelopmental disability among preterm infants with PHVD and PHH.METHODSThe study patients were preterm infants (< 36 weeks gestation) with IVH and PHVD, with or without PHH. Ventricular index (VI), anterior horn width (AHW), thalamooccipital distance (TOD), ventricle/brain (V/B) ratio, and resistive indices (RIs) were recorded on the head ultrasound (HUS) just prior to surgery, or the HUS capturing the worst PHVD when surgery was not indicated. The posterior fossa was assessed with MRI. Neonatal ICU Network Neurobehavioral Scale (NNNS) examinations were performed at term age equivalent for each infant. A neurodevelopmental assessment using the Capute Scales (Capute Cognitive Adaptive Test [CAT] scores and Capute Clinical Linguistic Auditory Milestone Scale [CLAMS] scores) and a motor quotient (MQ) assessment were performed between 3 and 6 months of age corrected for degree of prematurity (corrected age). MQs < 50 reflect moderate to severe delays in early motor milestone attainment, CAT scores < 85 reflect delays in early visual and problem-solving abilities, and CLAMS scores < 85 reflect delays in early language.RESULTSTwenty-one infants underwent assessments that included imaging and NNNS examinations, Capute Scales assessments, and MQs. NNNS nonoptimal reflexes (NOR) and hypertonicity subscores and AHW were associated with MQs < 50: NOR subscore OR 2.46 (95% CI 1.15–37.6, p = 0.034), hypertonicity subscore OR 1.68 (95% CI 1.04–3.78, p = 0.037), and AHW OR 1.13 (95% CI 1.01–1.39, p = 0.041). PVHI, cystic changes, and neurosurgical intervention were associated with CAT scores < 85: PVHI OR 9.2 (95% CI 1.2–73.2, p = 0.037); cystic changes OR 12.0 (95% CI 1.0–141.3, p = 0.048), and neurosurgical intervention OR 11.2 (95% CI 1.0–120.4, p = 0.046). Every 1-SD increase in the NOR subscore was associated with an increase in odds of a CAT score < 85, OR 4.0 (95% CI 1.0–15.0, p = 0.044). Worse NNNS NOR subscores were associated with early language delay: for a 1-SD increase in NOR subscore, there was an increase in the odds of a CLAMS score < 85, OR 19.5 (95% CI 1.3–303, p = 0.034).CONCLUSIONSIn former preterm children with severe IVH and PHVD, neonatal neurological examination findings and imaging features are associated with delays at 3–6 months in motor milestones, visual and problem-solving abilities, and language.

Neurosurgical intervention in penetrating spinal trauma with associated visceral injury

1989 ◽  
Vol 70 (4) ◽  
pp. 514-518 ◽  
Author(s):  
Benjamin H. Venger ◽  
Richard K. Simpson ◽  
Raj K. Narayan
Keyword(s):  
Neurological Outcome ◽  
Cauda Equina ◽  
Neurological Deficits ◽  
Neurological Injury ◽  
Infection Prophylaxis ◽  
Associated Injuries ◽  
Visceral Injury ◽  
Surgical Exploration ◽  
Significant Difference ◽  
Neurosurgical Intervention

✓ Associated injuries to the neck, chest, or abdomen are found in approximately one-quarter of all civilians with penetrating spinal cord or cauda equina injuries. While the value of and indications for general surgical exploration and repair of these injuries are fairly self-evident, the value of neurosurgical intervention in terms of neurological outcome and infection prophylaxis remains the subject of debate. To study this issue, 160 civilian patients with penetrating spinal injuries and neurological deficits were retrospectively reviewed. Associated injuries of the esophagus, trachea, bronchi, or bowel were seen in 107 individuals (67%); 33 (31%) of these patients had abdominal injuries, 25 (23%) had neck injuries, 23 (21%) had thoracic injuries, and 26 (24%) had injuries occurring at multiple sites. Of these 107 patients, 67 (63%) had complete neurological injuries and the remaining 40 (37%) demonstrated incomplete deficits. All 107 patients underwent surgical exploration and repair of their visceral injuries; in 19 of them a neurosurgical procedure was also performed for decompression of the neural elements and/or debridement of the wound. Regardless of the presence of associated visceral injuries, the mechanism of injury, and the extent of the neurological deficit, no statistically significant difference in neurological outcome was found in patients with or without neurosurgical intervention. Complications associated with neurological injury were reported in 17 (11%) of the total group of 160 patients. Four (21%) of the 19 patients who had neurosurgical intervention suffered a related complication, compared to only six (7%) of the 88 patients who were managed conservatively (p < 0.05). Within the limitations of a retrospective review, the results of this study do not clearly support the value of routine neurosurgical intervention as an adjunct to general surgical repair in cases of spinal injury associated with penetrating visceral trauma.

scholarly journals MBL2 gene polymorphisms increase the risk of adverse neurological outcome in preterm infants: a preliminary prospective study

2014 ◽  
Vol 76 (5) ◽  
pp. 464-469 ◽  
Author(s):  
Cinzia Auriti ◽  
Giusi Prencipe ◽  
Barbara Caravale ◽  
Maria Franca Coletti ◽  
Maria Paola Ronchetti ◽  
...  
Keyword(s):  
Prospective Study ◽  
Preterm Infants ◽  
Neurological Outcome ◽  
Gene Polymorphisms ◽  
Mbl2 Gene

Neurological outcome at 6 and 12 months corrected age in hospitalised late preterm infants -a prospective study

2018 ◽  
Vol 22 (4) ◽  
pp. 602-609 ◽  
Author(s):  
Ilias Chatziioannidis ◽  
Maria Kyriakidou ◽  
Sotiria Exadaktylou ◽  
Evangelia Antoniou ◽  
Dimitrios Zafeiriou ◽  
...  
Keyword(s):  
Prospective Study ◽  
Preterm Infants ◽  
Neurological Outcome ◽  
Late Preterm ◽  
Late Preterm Infants ◽  
A Prospective Study

Ventricular dilatation in preterm infants

1993 ◽  
Vol 9 (6) ◽  
pp. 498
Author(s):  
Alan Leviton ◽  
Karl Kuban
Keyword(s):  
Preterm Infants ◽  
Ventricular Dilatation
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