scholarly journals Expression and therapeutic targeting of dopamine receptor-1 (D1R) in breast cancer

Oncogene ◽  
2015 ◽  
Vol 35 (24) ◽  
pp. 3103-3113 ◽  
Author(s):  
D C Borcherding ◽  
W Tong ◽  
E R Hugo ◽  
D F Barnard ◽  
S Fox ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dopamine Receptor ◽  
Therapeutic Targeting ◽  
Dopamine Receptor 1

scholarly journals Therapeutic Targeting of Osteopontin in Breast Cancer Cells

10.5772/21115 ◽  
2011 ◽  
Author(s):  
Gopal C. ◽  
Supriya Saraswati ◽  
Megha Sanyal ◽  
Anuradha Bulbule ◽  
Anuja Ramdasi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Therapeutic Targeting

scholarly journals The Evolving Role of Ferroptosis in Breast Cancer: Translational Implications Present and Future

Cancers ◽  
2021 ◽  
Vol 13 (18) ◽  
pp. 4576
Author(s):  
Hung-Yu Lin ◽  
Hui-Wen Ho ◽  
Yen-Hsiang Chang ◽  
Chun-Jui Wei ◽  
Pei-Yi Chu
Keyword(s):  
Breast Cancer ◽  
Cell Death ◽  
Regulatory Networks ◽  
Molecular Mechanisms ◽  
Drug Resistant ◽  
Therapeutic Targeting ◽  
The Past ◽  
Regulated Cell Death ◽  
Common Malignancy

Breast cancer (BC) is the most common malignancy among women worldwide. The discovery of regulated cell death processes has enabled advances in the treatment of BC. In the past decade, ferroptosis, a new form of iron-dependent regulated cell death caused by excessive lipid peroxidation has been implicated in the development and therapeutic responses of BC. Intriguingly, the induction of ferroptosis acts to suppress conventional therapy-resistant cells, and to potentiate the effects of immunotherapy. As such, pharmacological or genetic modulation targeting ferroptosis holds great potential for the treatment of drug-resistant cancers. In this review, we present a critical analysis of the current understanding of the molecular mechanisms and regulatory networks involved in ferroptosis, the potential physiological functions of ferroptosis in tumor suppression, its potential in therapeutic targeting, and explore recent advances in the development of therapeutic strategies for BC.

scholarly journals Decreased dopamine receptor 1 activity and impaired motor-skill transfer in Dyt1 ΔGAG heterozygous knock-in mice

2015 ◽  
Vol 279 ◽  
pp. 202-210 ◽  
Author(s):  
Fumiaki Yokoi ◽  
Mai T. Dang ◽  
Jun Liu ◽  
Jason R. Gandre ◽  
Kelly Kwon ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
Motor Skill ◽  
Skill Transfer ◽  
Dopamine Receptor 1

scholarly journals Postnatal developmental trajectory of dopamine receptor 1 and 2 expression in cortical and striatal brain regions

2018 ◽  
Vol 527 (6) ◽  
pp. 1039-1055 ◽  
Author(s):  
Ellen R. Cullity ◽  
Heather B. Madsen ◽  
Christina J. Perry ◽  
Jee Hyun Kim
Keyword(s):  
Dopamine Receptor ◽  
Brain Regions ◽  
Developmental Trajectory ◽  
Dopamine Receptor 1
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