scholarly journals MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo

Oncogene ◽  
2011 ◽  
Vol 31 (28) ◽  
pp. 3357-3369 ◽  
Author(s):  
X-X He ◽  
Y Chang ◽  
F-Y Meng ◽  
M-Y Wang ◽  
Q-H Xie ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Growth ◽  
Liver Cancer ◽  
Cancer Cell ◽  
Liver Cancer Cell ◽  
Cancer Cell Growth

scholarly journals Adenovirus-mediated delivery of siRNA targeting TM4SF4 attenuated liver cancer cell growth in vitro and in vivo

2013 ◽  
Vol 45 (3) ◽  
pp. 213-219 ◽  
Author(s):  
L. Wang ◽  
J. Feng ◽  
L. Da ◽  
Y. Li ◽  
Z. Li ◽  
...  
Keyword(s):  
Cell Growth ◽  
Liver Cancer ◽  
Cancer Cell ◽  
Liver Cancer Cell ◽  
Cancer Cell Growth

scholarly journals Veratramine suppresses human HepG2 liver cancer cell growth in vitro and in vivo by inducing autophagic cell death

2020 ◽  
Vol 44 (2) ◽  
pp. 477-486
Author(s):  
Linlin Yin ◽  
Yonghui Xia ◽  
Ping Xu ◽  
Wenli Zheng ◽  
Yuanyuan Gao ◽  
...  
Keyword(s):  
Cell Death ◽  
Cell Growth ◽  
Liver Cancer ◽  
Cancer Cell ◽  
Autophagic Cell Death ◽  
Liver Cancer Cell ◽  
Cancer Cell Growth

Inhibiting effect of MicroRNA-3619-5p/PSMD10 axis on liver cancer cell growth in vivo and in vitro

Life Sciences ◽  
2020 ◽  
Vol 254 ◽  
pp. 117632 ◽  
Author(s):  
Peipei Hao ◽  
Fengming Yue ◽  
Xian Xian ◽  
Qian Ren ◽  
Huixian Cui ◽  
...  
Keyword(s):  
Cell Growth ◽  
Liver Cancer ◽  
Cancer Cell ◽  
Liver Cancer Cell ◽  
Cancer Cell Growth ◽  
Inhibiting Effect

794: Valproic Acid Inhibits Prostate Cancer Cell Growth in Vitro and in Vivo

2006 ◽  
Vol 175 (4S) ◽  
pp. 257-257
Author(s):  
Jennifer Sung ◽  
Qinghua Xia ◽  
Wasim Chowdhury ◽  
Shabana Shabbeer ◽  
Michael Carducci ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Valproic Acid ◽  
Cell Growth ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Growth

scholarly journals HOXB4 inhibits the proliferation and tumorigenesis of cervical cancer cells by downregulating the activity of Wnt/β-catenin signaling pathway

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Dan Lei ◽  
Wen-Ting Yang ◽  
Peng-Sheng Zheng
Keyword(s):  
Cervical Cancer ◽  
Cell Growth ◽  
Signaling Pathway ◽  
Cancer Cell ◽  
Tumor Formation ◽  
Cervical Cancer Cell ◽  
Cancer Cell Growth ◽  
Bioinformatics Analyses

AbstractHomeobox B4 (HOXB4), which belongs to the homeobox (HOX) family, possesses transcription factor activity and has a crucial role in stem cell self-renewal and tumorigenesis. However, its biological function and exact mechanism in cervical cancer remain unknown. Here, we found that HOXB4 was markedly downregulated in cervical cancer. We demonstrated that HOXB4 obviously suppressed cervical cancer cell proliferation and tumorigenic potential in nude mice. Additionally, HOXB4-induced cell cycle arrest at the transition from the G0/G1 phase to the S phase. Conversely, loss of HOXB4 promoted cervical cancer cell growth both in vitro and in vivo. Bioinformatics analyses and mechanistic studies revealed that HOXB4 inhibited the activity of the Wnt/β-catenin signaling pathway by direct transcriptional repression of β-catenin. Furthermore, β-catenin re-expression rescued HOXB4-induced cervical cancer cell defects. Taken together, these findings suggested that HOXB4 directly transcriptional repressed β-catenin and subsequently inactivated the Wnt/β-catenin signaling pathway, leading to significant inhibition of cervical cancer cell growth and tumor formation.

microRNA 21-mediated suppression of sprouty1 by Pokemon affects liver cancer cell growth and proliferation

2013 ◽  
Vol 114 (7) ◽  
pp. 1625-1633 ◽  
Author(s):  
Xiu-Li Jin ◽  
Qin-Sheng Sun ◽  
Feng Liu ◽  
Hong-Wei Yang ◽  
Min Liu ◽  
...  
Keyword(s):  
Cell Growth ◽  
Liver Cancer ◽  
Cancer Cell ◽  
Liver Cancer Cell ◽  
Cancer Cell Growth ◽  
Cell Growth And Proliferation
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