scholarly journals Exercise, Abdominal Obesity, Skeletal Muscle, and Metabolic Risk: Evidence for a Dose Response

Obesity ◽  
2009 ◽  
Vol 17 (S3) ◽  
pp. S27-S33 ◽  
Author(s):  
Cris A. Slentz ◽  
Joseph A. Houmard ◽  
William E. Kraus
Keyword(s):  
Skeletal Muscle ◽  
Abdominal Obesity ◽  
Dose Response ◽  
Metabolic Risk

scholarly journals Adiponectin, some markers of metabolic risk and abdominal obesity in preschool age

2016 ◽  
Vol 5 (1) ◽  
pp. 21
Author(s):  
Mina Lateva ◽  
Violeta Iotova ◽  
Ralitsa Popova ◽  
Sonya Galcheva ◽  
Miglena Georgieva ◽  
...  
Keyword(s):  
Abdominal Obesity ◽  
Preschool Age ◽  
Metabolic Risk

scholarly journals Resting heart rate is associated with the risk of metabolic syndrome and its components among Dong adults in southwest China: The China Multi-Ethnic Cohort (CMEC) Study

2021 ◽  
Author(s):  
Xiao Zhang ◽  
Feng Hong ◽  
Zixiu Qin ◽  
Leilei Liu ◽  
Jun Yang ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Heart Rate ◽  
Dose Response ◽  
Southwest China ◽  
Positive Association ◽  
Metabolic Risk ◽  
Resting Heart Rate ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Restricted Cubic Splines

Abstract Background High resting heart rate (RHR), one abnormal manifestation of autonomic nervous system, was associated with metabolic disorders. However, the association between RHR and metabolic syndrome (MetS) and its components remains controversial. This study aimed to explore the link between RHR and MetS and its components. Methods The study included 6,589 Dong adults (1,434 patients) from the China Multi-Ethnic Cohort (CMEC) Study. Logistic regression model was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) and assess the association between RHR and MetS, clustered metabolic risk, and MetS components. Restricted cubic splines model was used to evaluate the dose–response relationship between RHR and MetS and its components. Results A positive association existed between RHR and MetS, and people in the highest RHR quartile had a higher MetS risk (OR 1.75 [95% CI 1.42–2.15]) than those in the lowest quartile. The clustered metabolic risk associated with RHR (P < 0.05). Furthermore, RHR was related to elevated blood pressure (BP), elevated triglycerides (TG), and elevated fasting plasma glucose (FPG), the ORs (95% CIs) for the highest versus lowest RHR quartile were 2.06 (1.75–2.43), 1.37 (1.17–1.62), and 2.53 (2.04–3.14), respectively. Similar results were found in sensitivity and subgroup analyses. Also, non-linear dose-response relationship existed between RHR and MetS and elevated levels of BP, TG, and FPG (P < 0.001). Conclusions RHR was related to the risk of MetS and three MetS components (elevated BP, elevated TG, and elevated FPG). RHR may be a useful indicator for MetS.

Skeletal muscle ceramide species in men with abdominal obesity

2014 ◽  
Vol 19 (4) ◽  
pp. 389-396 ◽  
Author(s):  
Maria Pia de la Maza ◽  
J. M. Rodriguez ◽  
S. Hirsch ◽  
L. Leiva ◽  
G. Barrera ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Abdominal Obesity

Alterations in the functional properties of skinned fibers from denervated rabbit skeletal muscle

1990 ◽  
Vol 259 (3) ◽  
pp. C503-C506 ◽  
Author(s):  
M. M. Trachez ◽  
R. T. Sudo ◽  
G. Suarez-Kurtz
Keyword(s):  
Skeletal Muscle ◽  
Sarcoplasmic Reticulum ◽  
Functional Properties ◽  
Dose Response ◽  
Response Curve ◽  
Extensor Digitorum Longus ◽  
Isometric Tension ◽  
Skinned Fibers ◽  
Spontaneous Release

Isometric tension was recorded in vitro from chemically skinned fibers obtained from normal and 14-day-denervated extensor digitorum longus muscles of the rabbit. Denervation potentiated the tensions elicited by pCa 6.0 but did not modify the pCa value (5.6) required for maximum tension. Ca2+ transport across the membranes of the sarcoplasmic reticulum (SR) was markedly affected by denervation. Thus the rate of ATP-dependent net Ca2+ uptake increased significantly, and the spontaneous release ("leakage") of the Ca2+ stored in the SR was significantly reduced in denervated fibers. These effects lead to increased accumulation of Ca2+ in the lumen of the SR. The dose-response curve for the halothane-induced contractures of Ca2(+)-loaded skinned fibers was displaced to the left after denervation. Thus 0.7 mM halothane, a concentration that elicited no tension in 10 control fibers, induced contractures in the 10 denervated fibers tested. The potentiation of the halothane-induced tensions is attributed mainly to the larger stores of Ca2+ in the SR of denervated fibers. The possibility that denervation may also affect the interaction of halothane with the SR membranes is discussed.

Dynapenic Abdominal Obesity and Metabolic Risk Factors in Adults 50 Years of Age and Older

2012 ◽  
Vol 24 (5) ◽  
pp. 812-826 ◽  
Author(s):  
Martin Sénéchal ◽  
Isabelle J. Dionne ◽  
Martin Brochu
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Abdominal Obesity ◽  
Type Ii Diabetes ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Lower Plasma ◽  
Glucose Levels ◽  
Health And Nutrition ◽  
Dependent Variables

Objectives: To investigate the additive effect of dynapenia and abdominal obesity on metabolic risk factors in older adults. Method: A total of 3,007 men and women from the National Health and Nutrition Examination Survey (NHANES) study were categorized as follows: (a) non-dynapenic/non-abdominally obese (N-DYN/N-AO), (b) dynapenic/non-abdominally obese (DYN/N-AO), (c) non-dynapenic/abdominally obese (N-DYN/AO), (d) dynapenic/ abdominally obese (DYN/AO) based on waist circumference (WC) and leg muscle strength tertiles. Dependent variables were lipids, glucose, blood pressure, and other chronic conditions. Results: The DYN/AO group had lower plasma HDL-chol and higher triglyceride and glucose levels than N-DYN/N-AO and DYN/N-AO groups (all p ≤ .01). Higher plasma triglyceride was observed in the DYN/AO group compared with N-DYN/AO group ( p ≤ .01). The odds of having metabolic syndrome, cardiovascular diseases, and type II diabetes were higher in DYN/AO compared with DYN/N-AO and N-DYN/N-AO. Conclusion: DYN/AO older adults might be at greater risk of metabolic alterations than those displaying dynapenia alone or those with neither abdominal obesity nor dynapenia.

scholarly journals Intra-abdominal obesity and metabolic risk factors: a study of young adults

2003 ◽  
Vol 27 (8) ◽  
pp. 941-949 ◽  
Author(s):  
F E von Eyben ◽  
E Mouritsen ◽  
J Holm ◽  
P Montvilas ◽  
G Dimcevski ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Abdominal Obesity ◽  
Metabolic Risk Factors ◽  
Metabolic Risk
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