Effect of a Conjugated Linoleic Acid and ω-3 Fatty Acid Mixture on Body Composition and Adiponectin

Obesity ◽  
2008 ◽  
Vol 16 (5) ◽  
pp. 1019-1024 ◽  
Author(s):  
Alan A. Sneddon ◽  
Fotini Tsofliou ◽  
Claire L. Fyfe ◽  
Ian Matheson ◽  
Diane M. Jackson ◽  
...  
Keyword(s):  
Body Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Fatty Acid Mixture ◽  
Acid Mixture

scholarly journals Mechanisms of Anticancer Activity of a Fatty Acid Mixture Extracted from Hen Egg Yolks Enriched in Conjugated Linoleic Acid Diene (CLA) against WM793 Melanoma Cells

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2348
Author(s):  
Dominik Domagała ◽  
Teresa Leszczyńska ◽  
Aneta Koronowicz ◽  
Barbara Domagała ◽  
Mariola Drozdowska ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Cancer Cells ◽  
Conjugated Linoleic Acid ◽  
Egg Yolk ◽  
Mitochondrial Pathway ◽  
Fatty Acid Mixture ◽  
Biologically Active ◽  
Acid Mixture

The conjugated linoleic acid (CLA) diene is a biologically active compound with proven health-promoting effects. In terms of anticancer properties, it has been shown that CLA reduces the proliferation of cancer cells. In this study, it has been demonstrated that a mixture of fatty acids, isolated from chicken egg yolk enriched in CLA isomers by biofortification, reduces (by 30.5%) the proliferation of human melanoma cancer cells line WM793 to a greater extent than a mixture of fatty acids not containing these isomers. At the same time, the tested fatty acid mixtures show no effect on human normal BJ fibroblast cells. For the first time, the genes with increased expression have been identified and the proteins have been activated by the fatty acid mixture of CLA-enriched egg yolk, mainly responsible for mitochondrial pathway-dependent apoptosis.

scholarly journals Trans-8,cis-10+cis-9,trans-11-conjugated linoleic acid mixture alters body composition in Syrian golden hamsters fed a hypercholesterolaemic diet

2010 ◽  
Vol 104 (10) ◽  
pp. 1443-1449 ◽  
Author(s):  
Shama V. Joseph ◽  
Xiaoran Liu ◽  
Andrew Wakefield ◽  
P. Yvan Chouinard ◽  
Harold Aukema ◽  
...  
Keyword(s):  
Body Composition ◽  
Linoleic Acid ◽  
Lipid Profile ◽  
Conjugated Linoleic Acid ◽  
Fat Mass ◽  
Cholesterol Concentration ◽  
Safflower Seed ◽  
Acid Mixture ◽  
Golden Hamsters ◽  
Syrian Golden Hamsters

The effectiveness of conjugated linoleic acid (CLA) as a weight-loss nutraceutical continues to be debatable, suggesting that there may be value in exploring the physiological effects of the lesser-known isomers. The effects of the minor isomer,trans-8,cis-10 (t8,c10)-CLA, in the form of an equimolar mixture with thecis-9,trans-11 (c9,t11) isomer, on body weight and body composition, circulating glucose and lipid concentrations, and liver weights were studied in sixty male Syrian golden hamsters. Animals were randomised to receive for 28 d a semi-purified, hypercholesterolaemic diet (5 % dietary fat and 0·25 % cholesterol) supplemented at the 2 % level with either thet8,c10+c9,t11-CLA mixture,c9,t11-CLA ortrans-10,cis-12 (t10,c12)-CLA replacing lard and safflower-seed oil (control). Results show that compared with control, thet8,c10+c9,t11-CLA mixture andt10,c12-CLA-fed animals had lower (P < 0·0001) fat mass following supplementation. Animals consumingt10,c12-CLA also possessed higher lean mass compared with control andc9,t11-CLA groups (P < 0·001). However, the livers of these animals were larger (P < 0·0001) compared with those in the control and other CLA groups. Body weights of the hamsters did not differ across the experimental groups. CLA treatments had no effect on serum glucose or lipid profile, except for inducing higher (P < 0·05) non-HDL-cholesterol concentration witht10,c12-CLA compared with thec9,t11 isomer. Overall, these results indicate that in male hamsters fed a hypercholesterolaemic diet, thet8,c10+c9,t11-CLA mixture does not have an impact on blood lipid profile, but is able to effectively reduce fat mass, without incurring an accompanying liver enlargement.

Effect of slaughter season on fatty acid composition, conjugated linoleic acid isomers and nutritional value of intramuscular fat in Barrosã-PDO veal

Meat Science ◽  
2007 ◽  
Vol 75 (1) ◽  
pp. 44-52 ◽  
Author(s):  
Cristina M.M. Alfaia ◽  
Matilde L.F. Castro ◽  
Susana I.V. Martins ◽  
Ana P.V. Portugal ◽  
Susana P.A. Alves ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Acid Composition ◽  
Nutritional Value ◽  
Intramuscular Fat

scholarly journals Effects of Conjugated Linoleic Acid. 1. Fatty Acid Modification of Yolks and Neonatal Fatty Acid Metabolism

2000 ◽  
Vol 79 (6) ◽  
pp. 817-821 ◽  
Author(s):  
M.A. Latour ◽  
A.A. Devitt ◽  
R.A. Meunier ◽  
J.J. Stewart ◽  
B.A. Watkins
Keyword(s):  
Fatty Acid ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Fatty Acid Metabolism ◽  
Acid Metabolism ◽  
Acid Modification ◽  
Fatty Acid Modification
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