PDZ domain proteins of synapses

2004 ◽  
Vol 5 (10) ◽  
pp. 771-781 ◽  
Author(s):  
Eunjoon Kim ◽  
Morgan Sheng
Keyword(s):  
Pdz Domain ◽  
Pdz Domain Proteins

scholarly journals Signaling Complex Organization by PDZ Domain Proteins

Neurosignals ◽  
2002 ◽  
Vol 11 (6) ◽  
pp. 315-321 ◽  
Author(s):  
Jing-Song Fan ◽  
Mingjie Zhang
Keyword(s):  
Pdz Domain ◽  
Signaling Complex ◽  
Complex Organization ◽  
Pdz Domain Proteins

scholarly journals Human Papillomavirus E6 interaction with cellular PDZ domain proteins modulates YAP nuclear localization

Virology ◽  
2018 ◽  
Vol 516 ◽  
pp. 127-138 ◽  
Author(s):  
Sydney Webb Strickland ◽  
Nicole Brimer ◽  
Charles Lyons ◽  
Scott B. Vande Pol
Keyword(s):  
Human Papillomavirus ◽  
Nuclear Localization ◽  
Pdz Domain ◽  
Pdz Domain Proteins

Targeting PDZ Domain Proteins for Treating NMDA Receptor-Mediated Excitotoxicity

2006 ◽  
Vol 6 (7) ◽  
pp. 711-721 ◽  
Author(s):  
Wenyu Wen ◽  
Wenning Wang ◽  
Mingjie Zhang
Keyword(s):  
Nmda Receptor ◽  
Pdz Domain ◽  
Pdz Domain Proteins

T7 phage display as a method of peptide ligand discovery for PDZ domain proteins

Biopolymers ◽  
2009 ◽  
Vol 92 (3) ◽  
pp. 183-193 ◽  
Author(s):  
Sudhir C. Sharma ◽  
Adnan Memic ◽  
Chamila N. Rupasinghe ◽  
Anne-Cécile E. Duc ◽  
Mark R. Spaller
Keyword(s):  
Phage Display ◽  
Pdz Domain ◽  
Peptide Ligand ◽  
Pdz Domain Proteins ◽  
Ligand Discovery ◽  
T7 Phage Display ◽  
T7 Phage

scholarly journals 0150: PDZ domain proteins interacting with Nav1.5 differentially regulate Nav1.5 channel pools in mouse cardiomyocytes

2014 ◽  
Vol 6 ◽  
pp. 40-41
Author(s):  
Ludovic Gillet ◽  
Diana Shy ◽  
Stephan Sonntag ◽  
Jean-Sébastien Rougier ◽  
Arie Verkerk ◽  
...  
Keyword(s):  
Pdz Domain ◽  
Pdz Domain Proteins

scholarly journals Association of ARVCF with Zonula Occludens (ZO)-1 and ZO-2: Binding to PDZ-Domain Proteins and Cell-Cell Adhesion Regulate Plasma Membrane and Nuclear Localization of ARVCF

2004 ◽  
Vol 15 (12) ◽  
pp. 5503-5515 ◽  
Author(s):  
P. Jaya Kausalya ◽  
Dominic C.Y. Phua ◽  
Walter Hunziker
Keyword(s):  
Plasma Membrane ◽  
Cell Adhesion ◽  
Nuclear Localization ◽  
Pdz Domain ◽  
Cell Contact ◽  
Binding Motif ◽  
Zonula Occludens ◽  
Pdz Domain Proteins ◽  
E Cadherin ◽  
Cell Cell

ARVCF, an armadillo-repeat protein of the p120ctnfamily, associates with classical cadherins and is present in adherens junctions, but its function is poorly understood. Here, we show that ARVCF interacts via a C-terminal PDZ-binding motif with zonula occludens (ZO)-1 and ZO-2. ARVCF and ZO-1 partially colocalize in the vicinity of the apical adhesion complex in polarized epithelial Madin-Darby canine kidney cells. ARVCF, ZO-1, and E-cadherin form a complex and are recruited to sites of initial cell-cell contact in sparse cell cultures. E-cadherin binding and plasma membrane localization of ARVCF require the PDZ-binding motif. Disruption of cell-cell adhesion releases ARVCF from the plasma membrane and an increased fraction of the protein localizes to the nucleus. Nuclear localization of ARVCF also requires the PDZ-binding motif and can be mediated by the PDZ domains of ZO-2. Thus, the interaction of ARVCF with distinct PDZ-domain proteins determines its subcellular localization. Interactions with ZO-1 and ZO-2, in particular, may mediate recruitment of ARVCF to the plasma membrane and the nucleus, respectively, possibly in response to cell-cell adhesion cues.

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