scholarly journals A gene-centric analysis of transcriptional cascades

2016 ◽  
Vol 17 (4) ◽  
pp. 193-193
Author(s):  
Ross Cloney
Keyword(s):  
Transcriptional Cascades

Proteomic signals in simple transcriptional cascades

2009 ◽  
Vol 41 (4) ◽  
pp. 1823-1827 ◽  
Author(s):  
A.S. Carstea ◽  
A. Ramani ◽  
K.M. Tamizhmani ◽  
B. Grammaticos
Keyword(s):  
Transcriptional Cascades

scholarly journals Identification of the Novel Player δEF1 in Estrogen Transcriptional Cascades

1999 ◽  
Vol 19 (5) ◽  
pp. 3600-3606 ◽  
Author(s):  
Elaine M. Chamberlain ◽  
Michel M. Sanders
Keyword(s):  
Estrogen Receptor ◽  
Transcription Factor ◽  
Binding Site ◽  
Target Gene ◽  
Transcriptional Level ◽  
Receptor Complex ◽  
The Novel ◽  
Regulatory Cascade ◽  
Transcriptional Cascades

ABSTRACT Although many genes are regulated by estrogen, very few have been shown to directly bind the estrogen receptor complex. Therefore, transcriptional cascades probably occur in which the estrogen receptor directly binds to a target gene that encodes another transcription factor that subsequently regulates additional genes. Through the use of a differential display assay, a transcription factor has been identified that may be involved in estrogen transcriptional cascades. This report demonstrates that transcription factor δEF1 is induced eightfold by estrogen in the chick oviduct. Furthermore, the regulation by estrogen occurs at the transcriptional level and is likely to be a direct effect of the estrogen receptor complex, as it does not require concomitant protein synthesis. A putative binding site was identified in the 5′-flanking region of the chick ovalbumin gene identifying it as a possible target gene for regulation by δEF1. Characterization of this binding site revealed that δEF1 binds to and regulates the chick ovalbumin gene. Thus, a novel regulatory cascade that is triggered by estrogen has been defined.

scholarly journals On the role of topology in regulating transcriptional cascades

2017 ◽  
Vol 19 (36) ◽  
pp. 25168-25179 ◽  
Author(s):  
Mahan Ghafari ◽  
Alireza Mashaghi
Keyword(s):  
Response Profile ◽  
Signal Response ◽  
Topology Of Interactions ◽  
Transcriptional Cascades

Topology of interactions in a transcriptional cascade determines the behavior of its signal-response profile and the activation states of genes.

Transcriptional cascades in Drosophila

1993 ◽  
Vol 5 (3) ◽  
pp. 505-512 ◽  
Author(s):  
Herbert Jäckle ◽  
Frank Sauer
Keyword(s):  
Transcriptional Cascades

scholarly journals Re-using biological devices: a model-aided analysis of interconnected transcriptional cascades designed from the bottom-up

2017 ◽  
Vol 11 (1) ◽  
Author(s):  
Lorenzo Pasotti ◽  
Massimo Bellato ◽  
Michela Casanova ◽  
Susanna Zucca ◽  
Maria Gabriella Cusella De Angelis ◽  
...  
Keyword(s):  
Bottom Up ◽  
Transcriptional Cascades
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