scholarly journals Covalent histone modifications — miswritten, misinterpreted and mis-erased in human cancers

2010 ◽  
Vol 10 (7) ◽  
pp. 457-469 ◽  
Author(s):  
Ping Chi ◽  
C. David Allis ◽  
Gang Greg Wang
Endocrinology ◽  
2010 ◽  
Vol 151 (6) ◽  
pp. 2946-2956 ◽  
Author(s):  
Madesh Belakavadi ◽  
Jason Saunders ◽  
Noah Weisleder ◽  
Preethi S. Raghava ◽  
Joseph D. Fondell

2005 ◽  
Vol 280 (23) ◽  
pp. 21689-21692 ◽  
Author(s):  
Michael Bulger

A small but growing number of loci that exhibit covalent histone modifications, such as hyperacetylation, over broad regions of 10 kb or more have been characterized. These hyperacetylated domains occur exclusively at loci containing highly expressed, tissue-specific genes, and the available evidence suggests that they are involved in the activation of these genes. Although to date little is known concerning the formation or function of these domains, rather more is known concerning repressive, heterochromatic domains, and the example provided by heterochromatin may be instructive in considering mechanisms of active domain formation.


Nature ◽  
10.1038/47412 ◽  
2000 ◽  
Vol 403 (6765) ◽  
pp. 41-45 ◽  
Author(s):  
Brian D. Strahl ◽  
C. David Allis

2004 ◽  
Vol 69 (0) ◽  
pp. 161-170 ◽  
Author(s):  
Y. WANG ◽  
J. WYSOCKA ◽  
J.R. PERLIN ◽  
L. LEONELLI ◽  
C.D. ALLIS ◽  
...  

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