The language of covalent histone modifications

Nature ◽  
10.1038/47412 ◽  
2000 ◽  
Vol 403 (6765) ◽  
pp. 41-45 ◽  
Author(s):  
Brian D. Strahl ◽  
C. David Allis
Keyword(s):  
Histone Modifications ◽  
Covalent Histone Modifications

scholarly journals Repression of Cardiac Phospholamban Gene Expression Is Mediated by Thyroid Hormone Receptor-α1 and Involves Targeted Covalent Histone Modifications

Endocrinology ◽  
2010 ◽  
Vol 151 (6) ◽  
pp. 2946-2956 ◽  
Author(s):  
Madesh Belakavadi ◽  
Jason Saunders ◽  
Noah Weisleder ◽  
Preethi S. Raghava ◽  
Joseph D. Fondell
Keyword(s):  
Gene Expression ◽  
Thyroid Hormone ◽  
Histone Modifications ◽  
Hormone Receptor ◽  
Thyroid Hormone Receptor ◽  
Covalent Histone Modifications

scholarly journals Hyperacetylated Chromatin Domains: Lessons from Heterochromatin

2005 ◽  
Vol 280 (23) ◽  
pp. 21689-21692 ◽  
Author(s):  
Michael Bulger
Keyword(s):  
Histone Modifications ◽  
Domain Formation ◽  
Chromatin Domains ◽  
Tissue Specific ◽  
Hyperacetylated Domains ◽  
Covalent Histone Modifications

A small but growing number of loci that exhibit covalent histone modifications, such as hyperacetylation, over broad regions of 10 kb or more have been characterized. These hyperacetylated domains occur exclusively at loci containing highly expressed, tissue-specific genes, and the available evidence suggests that they are involved in the activation of these genes. Although to date little is known concerning the formation or function of these domains, rather more is known concerning repressive, heterochromatic domains, and the example provided by heterochromatin may be instructive in considering mechanisms of active domain formation.

scholarly journals Linking Covalent Histone Modifications to Epigenetics: The Rigidity and Plasticity of the Marks

2004 ◽  
Vol 69 (0) ◽  
pp. 161-170 ◽  
Author(s):  
Y. WANG ◽  
J. WYSOCKA ◽  
J.R. PERLIN ◽  
L. LEONELLI ◽  
C.D. ALLIS ◽  
...  
Keyword(s):  
Histone Modifications ◽  
Covalent Histone Modifications

scholarly journals Covalent Histone Modifications Underlie the Developmental Regulation of Insulin Gene Transcription in Pancreatic β Cells

2003 ◽  
Vol 278 (26) ◽  
pp. 23617-23623 ◽  
Author(s):  
Swarup K. Chakrabarti ◽  
Joshua Francis ◽  
Suzanne M. Ziesmann ◽  
James C. Garmey ◽  
Raghavendra G. Mirmira
Keyword(s):  
Gene Transcription ◽  
Histone Modifications ◽  
Developmental Regulation ◽  
Insulin Gene ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Covalent Histone Modifications ◽  
Insulin Gene Transcription
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