Toll-like Receptor 4 Mediates Morphine-Induced Neuroinflammation and Tolerance via Soluble Tumor Necrosis Factor Signaling

Lori N Eidson; Kiyoshi Inoue; Larry J Young; Malu G Tansey; Anne Z Murphy

doi:10.1038/npp.2016.131

Toll-like Receptor 4 Mediates Morphine-Induced Neuroinflammation and Tolerance via Soluble Tumor Necrosis Factor Signaling

Neuropsychopharmacology ◽

10.1038/npp.2016.131 ◽

2016 ◽

Vol 42 (3) ◽

pp. 661-670 ◽

Cited By ~ 48

Author(s):

Lori N Eidson ◽

Kiyoshi Inoue ◽

Larry J Young ◽

Malu G Tansey ◽

Anne Z Murphy

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Tumor Necrosis Factor Signaling ◽

Necrosis Factor

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Polysaccharides fromDioscorea batatasInduce Tumor Necrosis Factor-α Secretion via Toll-like Receptor 4-Mediated Protein Kinase Signaling Pathways

Journal of Agricultural and Food Chemistry ◽

10.1021/jf8018722 ◽

2008 ◽

Vol 56 (21) ◽

pp. 9892-9898 ◽

Cited By ~ 27

Author(s):

Ju-Yun Liu ◽

Feng-Ling Yang ◽

Chun-Ping Lu ◽

Yu-Liang Yang ◽

Chi-Luan Wen ◽

...

Keyword(s):

Protein Kinase ◽

Tumor Necrosis Factor ◽

Signaling Pathways ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Α ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Factor Α ◽

Protein Kinase Signaling ◽

Necrosis Factor

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Deficient Tumor Necrosis Factor-α Production in Lipoarabinomannan Activated Macrophages from Toll-like Receptor-4 Deficient Mice: Implication for Mycobacterial Susceptibility

International Journal of Leprosy and Other Mycobacterial Diseases ◽

10.1489/1544-581x(2003)71<1:dtnfpi>2.0.co;2 ◽

2003 ◽

Vol 71 (1) ◽

pp. 1 ◽

Cited By ~ 3

Author(s):

William Levis ◽

Georgia B. Schuller-Levis ◽

Eunkyue Park

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Α ◽

Activated Macrophages ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Factor Α ◽

Deficient Mice ◽

Necrosis Factor

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Regulation of Lipopolysaccharide-Induced Translation of Tumor Necrosis Factor-Alpha by the Toll-Like Receptor 4 Adaptor Protein TRAM

Journal of Innate Immunity ◽

10.1159/000324833 ◽

2011 ◽

Vol 3 (5) ◽

pp. 437-446 ◽

Cited By ~ 14

Author(s):

Lijian Wang ◽

Estela Trebicka ◽

Ying Fu ◽

Lisa Waggoner ◽

Shizuo Akira ◽

...

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis Factor Alpha ◽

Tumor Necrosis ◽

Adaptor Protein ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Necrosis Factor Alpha ◽

Factor Alpha ◽

Necrosis Factor

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Hantaan virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon, interleukin-6 and tumor necrosis factor-alpha

Virology ◽

10.1016/j.virol.2008.07.002 ◽

2008 ◽

Vol 380 (1) ◽

pp. 52-59 ◽

Cited By ~ 28

Author(s):

Hong Jiang ◽

Ping-Zhong Wang ◽

Ye Zhang ◽

Zhe Xu ◽

Li Sun ◽

...

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis Factor Alpha ◽

Tumor Necrosis ◽

Hantaan Virus ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Necrosis Factor Alpha ◽

Enhanced Production ◽

Factor Alpha ◽

Necrosis Factor

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Ibudilast, a Phosphodiesterase Inhibitor and Toll-Like Receptor-4 Antagonist, Improves Hemorrhagic Shock and Reperfusion-Induced Left Ventricular Dysfunction by Reducing Myocardial Tumor Necrosis Factor α

Transplantation Proceedings ◽

10.1016/j.transproceed.2020.02.145 ◽

2020 ◽

Vol 52 (6) ◽

pp. 1869-1874 ◽

Cited By ~ 1

Author(s):

Nan-Chun Wu ◽

Jiun-Jr Wang

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Α ◽

Ventricular Dysfunction ◽

Phosphodiesterase Inhibitor ◽

Left Ventricular ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Factor Α ◽

Necrosis Factor

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NOT TOLL-LIKE RECEPTOR 4 NOR CD14 GENE POLYMORPHISMS BUT TUMOR NECROSIS FACTOR AND INTER-LEUKINE-10 GENE POLYMORPHISMS HAVE INFLUENCE ON CLINICAL OUTCOME OF SEPSIS

Critical Care Medicine ◽

10.1097/00003246-200412001-00047 ◽

2004 ◽

Vol 32 (Supplement) ◽

pp. A12

Author(s):

Taka-aki Nakada ◽

Hiroyuki Hirasawa ◽

Shigeto Oda ◽

Eizo Watanabe ◽

Ryuzo Abe

Keyword(s):

Tumor Necrosis Factor ◽

Clinical Outcome ◽

Gene Polymorphisms ◽

Tumor Necrosis ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Cd14 Gene ◽

Necrosis Factor

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Propofol suppresses tumor necrosis factor-α biosynthesis in lipopolysaccharide-stimulated macrophages possibly through downregulation of nuclear factor-kappa B-mediated toll-like receptor 4 gene expression

Chemico-Biological Interactions ◽

10.1016/j.cbi.2009.05.003 ◽

2009 ◽

Vol 180 (3) ◽

pp. 465-471 ◽

Cited By ~ 29

Author(s):

Gong-Jhe Wu ◽

Ta-Liang Chen ◽

Chia-Chen Chang ◽

Ruei-Ming Chen

Keyword(s):

Gene Expression ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Α ◽

Nuclear Factor Kappa B ◽

Nuclear Factor ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Factor Α ◽

Necrosis Factor

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Fumigaclavine C inhibits tumor necrosis factor α production via suppression of toll-like receptor 4 and nuclear factor κB activation in macrophages

Life Sciences ◽

10.1016/j.lfs.2011.06.015 ◽

2011 ◽

Vol 89 (7-8) ◽

pp. 235-240 ◽

Cited By ~ 17

Author(s):

Rong Hui Du ◽

Er Guang Li ◽

Yin Cao ◽

Yong Chun Song ◽

Ren Xiang Tan

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Α ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Factor Α ◽

Necrosis Factor

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Ketamine inhibits tumor necrosis factor-α and interleukin-6 gene expressions in lipopolysaccharide-stimulated macrophages through suppression of toll-like receptor 4-mediated c-Jun N-terminal kinase phosphorylation and activator protein-1 activation

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2007.11.027 ◽

2008 ◽

Vol 228 (1) ◽

pp. 105-113 ◽

Cited By ~ 80

Author(s):

Gone-Jhe Wu ◽

Ta-Liang Chen ◽

Yune-Fang Ueng ◽

Ruei-Ming Chen

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Α ◽

Activator Protein 1 ◽

Toll Like Receptor ◽

Gene Expressions ◽

Toll Like Receptor 4 ◽

Factor Α ◽

Kinase Phosphorylation ◽

Necrosis Factor

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Toll-like Receptor 4 Mediates LPS-Induced Release of Nitric Oxide and Tumor Necrosis Factor-α by Embryonal Cardiomyocytes: Biological Significance and Clinical Implications in Human Pathology

Current Pharmaceutical Design ◽

10.2174/138161210790883624 ◽

2010 ◽

Vol 16 (7) ◽

pp. 766-774 ◽

Cited By ~ 15

Author(s):

M. Panaro ◽

N. Gagliardi ◽

C. Saponaro ◽

R. Calvello ◽

V. Mitolo ◽

...

Keyword(s):

Nitric Oxide ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Biological Significance ◽

Clinical Implications ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Human Pathology ◽

Necrosis Factor

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