scholarly journals Loudness Dependence of Auditory Evoked Potentials as Indicator of Central Serotonergic Neurotransmission: Simultaneous Electrophysiological Recordings and In Vivo Microdialysis in the Rat Primary Auditory Cortex

2008 ◽  
Vol 33 (13) ◽  
pp. 3176-3181 ◽  
Author(s):  
Alexander Wutzler ◽  
Christine Winter ◽  
Werner Kitzrow ◽  
Idun Uhl ◽  
Rainer J Wolf ◽  
...  
Keyword(s):  
Auditory Cortex ◽  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Primary Auditory Cortex ◽  
In Vivo Microdialysis ◽  
Serotonergic Neurotransmission ◽  
Electrophysiological Recordings ◽  
Loudness Dependence

scholarly journals Competition for neuronal resources: how hallucinations make themselves heard

2007 ◽  
Vol 190 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Daniela Hubl ◽  
Thomas Koenig ◽  
Werner K. Strik ◽  
Lester Melie Garcia ◽  
Thomas Dierks
Keyword(s):  
Auditory Cortex ◽  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Primary Auditory Cortex ◽  
Auditory Attention ◽  
Auditory Hallucinations ◽  
Auditory Stimuli ◽  
Simultaneous Occurrence ◽  
Auditory Verbal Hallucinations ◽  
External Stimuli

BackgroundHallucinations are perceptions in the absence of a corresponding external sensory stimulus. However, during auditory verbal hallucinations, activation of the primary auditory cortex has been described.AimsThe objective of this study was to investigate whether this activation of the auditory cortex contributes essentially to the character of hallucinations and attributes them to alien sources, or whether the auditory activation is a sign of increased general auditory attention to external sounds.MethodThe responsiveness of the auditory cortex was investigated by auditory evoked potentials (N100) during the simultaneous occurrence of hallucinations and external stimuli. Evoked potentials were computed separately for periods with and without hallucinations; N100 power, topography and brain electrical sources were analysed.ResultsHallucinations lowered the N100 amplitudes and changed the topography, presumably due to a reduced left temporal responsivity.ConclusionsThis finding indicates competition between auditory stimuli and hallucinations for physiological resources in the primary auditory cortex. The abnormal activation of the primary auditory cortex may thus be a constituent of auditory hallucinations.

Three-dimensional analysis of auditory-evoked potentials in rat neocortex

1990 ◽  
Vol 64 (5) ◽  
pp. 1527-1536 ◽  
Author(s):  
D. S. Barth ◽  
S. Di
Keyword(s):  
Auditory Cortex ◽  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Microelectrode Array ◽  
Three Dimensional ◽  
Primary Auditory Cortex ◽  
Pyramidal Cells ◽  
Fast Wave ◽  
Cell Groups ◽  
The Right

1. A 8 X 8-channel microelectrode array was used to map epicortical field potentials evoked by bilaterally presented click stimuli from a 8 X 8-mm2 area in the right parietotemporal neocortex of four rats. In two rats, a 16-channel microelectrode array was also inserted into primary auditory cortex to record the laminar profile of auditory evoked potentials (AEP). 2. The epicortical responses began with a positive-negative fast wave followed by a positive-negative slow wave, similar to the previously reported P1, N1, P2, N2 complex. Topographical distributions of the potentials at the peak of each of these waves were distinct, suggesting that they were produced by separate but overlapping populations of cells. 3. Laminar recording revealed the asynchronous participation of supragranular and infragranular pyramidal cells in the generation of the evoked-response complex. The surface-recorded P1 was primarily produced by supragranular cells and the N1, by infragranular cells. The P2 and N2 were produced by temporally overlapping contributions from both cell groups. 4. We conclude that middle-latency components of the AEP complex are produced by both sequential and parallel activation of subpopulations of pyramidal cells in primary auditory cortex.

Association of catechol-O-methyltransferase variants with loudness dependence of auditory evoked potentials

2008 ◽  
Vol 23 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Georg Juckel ◽  
Wolfram Kawohl ◽  
Ina Giegling ◽  
Paraskevi Mavrogiorgou ◽  
Christine Winter ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Loudness Dependence
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