Association of catechol-O-methyltransferase variants with loudness dependence of auditory evoked potentials

2008 ◽  
Vol 23 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Georg Juckel ◽  
Wolfram Kawohl ◽  
Ina Giegling ◽  
Paraskevi Mavrogiorgou ◽  
Christine Winter ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Loudness Dependence

scholarly journals Mismatch Negativity and Loudness Dependence of Auditory Evoked Potentials among Patients with Major Depressive Disorder, Bipolar II Disorder, and Bipolar I Disorder

2020 ◽  
Vol 10 (11) ◽  
pp. 789
Author(s):  
Yang Rae Kim ◽  
Young-Min Park
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Evoked Potentials ◽  
Mismatch Negativity ◽  
Auditory Evoked Potentials ◽  
Type I ◽  
Major Depressive ◽  
Serotonergic Activity ◽  
Related Potentials ◽  
Loudness Dependence

Mismatch negativity (MMN) and loudness dependence of auditory evoked potentials (LDAEP), which are event-related potentials, have been investigated as biomarkers. MMN indicates the pre-attentive function, while LDAEP may be an index of central serotonergic activity. This study aimed to test whether MMN and LDAEP are useful biological markers for distinguishing patients with bipolar disorder (BD) and major depressive disorder (MDD), as well as the relationship between MMN and LDAEP. Fifty-five patients with major depressive episodes, aged 20 to 65 years, who had MDD (n = 17), BD type II (BIID) (n = 27), and BD type I (BID) (n = 11), were included based on medical records. Patients with MDD had a higher MMN amplitude than those with BID. In addition, the MMN amplitude in F4 positively correlated with the Korean version of mood disorder questionnaire scores (r = 0.37, p = 0.014), while the MMN amplitude in F3 correlated negatively with LDAEP (r = −0.30, p = 0.024). The odds ratios for the BID group and some variables were compared with those for the MDD group using multinomial logistic regression analysis. As a result, a significant reduction of MMN amplitude was found under BID diagnosis compared to MDD diagnosis (p = 0.015). This study supported the hypothesis that MMN amplitude differed according to MDD, BIID, and BID, and there was a relationship between MMN amplitude and LDAEP. These findings also suggested that BID patients had a reduced automatic and pre-attentive processing associated with serotonergic activity or N-methyl-D-aspartate receptor.

scholarly journals Association between Cortical GABA and Loudness Dependence of Auditory Evoked Potentials (LDAEP) in Humans

2018 ◽  
Vol 21 (9) ◽  
pp. 809-813 ◽  
Author(s):  
Christine Wyss ◽  
Desmond H Y Tse ◽  
Frank Boers ◽  
Nadim J Shah ◽  
Irene Neuner ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Loudness Dependence

Loudness dependence of auditory evoked potentials in obsessive–compulsive disorder: a pilot study

2000 ◽  
Vol 93 (3) ◽  
pp. 209-216 ◽  
Author(s):  
Maria T Carrillo-de-la-Peña ◽  
Paraskevi Mavrogiorgou ◽  
Georg Juckel ◽  
Walter Hauke ◽  
Jürgen Gallinat ◽  
...  
Keyword(s):  
Pilot Study ◽  
Evoked Potentials ◽  
Obsessive Compulsive Disorder ◽  
Auditory Evoked Potentials ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Loudness Dependence

scholarly journals Association between BDNF Gene Polymorphisms and Serotonergic Activity Using Loudness Dependence of Auditory Evoked Potentials in Healthy Subjects

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e60340 ◽  
Author(s):  
Young-Min Park ◽  
Seung-Hwan Lee ◽  
Heon-Jeong Lee ◽  
Seung-Gul Kang ◽  
Jung-Ah Min ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Gene Polymorphisms ◽  
Healthy Subjects ◽  
Auditory Evoked Potentials ◽  
Bdnf Gene ◽  
Serotonergic Activity ◽  
Loudness Dependence
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