Mass spectrometry imaging goes three dimensional

2017 ◽  
Vol 14 (12) ◽  
pp. 1139-1140 ◽  
Author(s):  
Klaus Dreisewerd ◽  
Joanne Y Yew
Keyword(s):  
Mass Spectrometry ◽  
Mass Spectrometry Imaging ◽  
Three Dimensional

scholarly journals Three dimensional secondary ion mass spectrometry imaging (3D-SIMS) of Aedes aegypti ovarian follicles

2019 ◽  
Vol 34 (5) ◽  
pp. 874-883 ◽  
Author(s):  
Anthony Castellanos ◽  
Cesar E. Ramirez ◽  
Veronika Michalkova ◽  
Marcela Nouzova ◽  
Fernando G. Noriega ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Aedes Aegypti ◽  
Mass Spectrometry Imaging ◽  
Secondary Ion Mass Spectrometry ◽  
Three Dimensional ◽  
Vital Role ◽  
Reproductive Maturation ◽  
Sugar Feeding ◽  
Nutrient Reserves ◽  
Secondary Ion

The mobilization of nutrient reserves into the ovaries of Aedes aegypti mosquitoes after sugar-feeding plays a vital role in the female's reproductive maturation.

scholarly journals Experimental and Data Analysis Considerations for Three-Dimensional Mass Spectrometry Imaging in Biomedical Research

2020 ◽  
Author(s):  
D. R. N. Vos ◽  
S. R. Ellis ◽  
B. Balluff ◽  
R. M. A. Heeren
Keyword(s):  
Mass Spectrometry ◽  
Data Analysis ◽  
Biomedical Research ◽  
Mass Spectrometry Imaging ◽  
Three Dimensional ◽  
Sample Volume ◽  
Biological Processes ◽  
Full Sample ◽  
Single Slice ◽  
Molecular Complexity

Abstract Mass spectrometry imaging (MSI) enables the visualization of molecular distributions on complex surfaces. It has been extensively used in the field of biomedical research to investigate healthy and diseased tissues. Most of the MSI studies are conducted in a 2D fashion where only a single slice of the full sample volume is investigated. However, biological processes occur within a tissue volume and would ideally be investigated as a whole to gain a more comprehensive understanding of the spatial and molecular complexity of biological samples such as tissues and cells. Mass spectrometry imaging has therefore been expanded to the 3D realm whereby molecular distributions within a 3D sample can be visualized. The benefit of investigating volumetric data has led to a quick rise in the application of single-sample 3D-MSI investigations. Several experimental and data analysis aspects need to be considered to perform successful 3D-MSI studies. In this review, we discuss these aspects as well as ongoing developments that enable 3D-MSI to be routinely applied to multi-sample studies.

Three-Dimensional Mass Spectrometry Imaging Of Lipids In Mouse Aortic Atherosclerotic Plaque

2019 ◽  
Vol 287 ◽  
pp. e29
Author(s):  
J. Cao ◽  
P. Goossens ◽  
M. Martin-Lorenzo ◽  
K. Ščupáková ◽  
F. Dewez ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Atherosclerotic Plaque ◽  
Mass Spectrometry Imaging ◽  
Three Dimensional

Fabrication of homogenous three-dimensional biomimetic tissue for mass spectrometry imaging

2019 ◽  
Vol 54 (5) ◽  
pp. 378-388 ◽  
Author(s):  
Xiaowei Song ◽  
Jiuming He ◽  
Chao Li ◽  
Chenglong Sun ◽  
Xuechao Pang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Mass Spectrometry Imaging ◽  
Three Dimensional

scholarly journals Characterization of an Aggregated Three-Dimensional Cell Culture Model by Multimodal Mass Spectrometry Imaging

2020 ◽  
Vol 92 (18) ◽  
pp. 12538-12547 ◽  
Author(s):  
Lucy E. Flint ◽  
Gregory Hamm ◽  
Joseph D. Ready ◽  
Stephanie Ling ◽  
Catherine J. Duckett ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Cell Culture ◽  
Mass Spectrometry Imaging ◽  
Three Dimensional ◽  
Cell Culture Model ◽  
Culture Model ◽  
Dimensional Cell
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