Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging

2009 ◽  
Vol 9 (2) ◽  
pp. 172-178 ◽  
Author(s):  
Patricia Horcajada ◽  
Tamim Chalati ◽  
Christian Serre ◽  
Brigitte Gillet ◽  
Catherine Sebrie ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Porous Metal ◽  
Metal Organic ◽  
Organic Framework

Metal Organic Framework [Zn2(1,4-bdc)2(dabco)]n as Drug Delivery System

2013 ◽  
Vol 829 ◽  
pp. 247-250 ◽  
Author(s):  
Negar Motakef-Kazemi ◽  
Seyed Abbas Shojaosadati ◽  
Ali Morsali
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Body Fluid ◽  
Metal Organic Framework ◽  
Porous Metal ◽  
Loading Efficiency ◽  
Metal Organic ◽  
Solvothermal Conditions ◽  
Organic Framework

Porous metal organic framework (MOF) {Zn2(1,4-bdc)2(dabco)}n synthesized under solvothermal conditions. The MOF was used as the carrier matrices for drug delivery system. The ibuprofen as analgesic and anti-inflammatory drug with 0.6 nm molecule size as a model was entrapped into this new carrier with pores distribution of 1.85 nm. The ibuprofen loading efficiency was obtained by thermogravimetric analysis. The ibuprofen loading efficiency of 22% (w/w) was obtained for this MOF. The entrapped ibuprofen was released over several days by soaking the sample in the simulated body fluid (pH 7.4) at 37 °C. The ibuprofen concentrations were analyzed using UV-vis Spectrophotometer at a wavelength of 260 nm. The result of release reveals that this {Zn2(1,4-bdc)2(dabco)}n is suitable as drug delivery system.

β-Cyclodextrin-based Metal-Organic Framework as a Carrier for Zero-order Drug Delivery

2021 ◽  
pp. 129766
Author(s):  
Yanyi Li ◽  
Haobin Huang ◽  
Chongwei Ding ◽  
Xiaoping Zhou ◽  
Hong Li
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Zero Order ◽  
Metal Organic ◽  
Organic Framework

Multifunctionality in an Ion-Exchanged Porous Metal–Organic Framework

2021 ◽  
Vol 143 (3) ◽  
pp. 1365-1376
Author(s):  
Sérgio M. F. Vilela ◽  
Jorge A. R. Navarro ◽  
Paula Barbosa ◽  
Ricardo F. Mendes ◽  
Germán Pérez-Sánchez ◽  
...  
Keyword(s):  
Metal Organic Framework ◽  
Porous Metal ◽  
Metal Organic ◽  
Organic Framework

Unusual pore structure and sorption behaviour in a hexanodal zinc–organic framework material

2014 ◽  
Vol 50 (14) ◽  
pp. 1678-1681 ◽  
Author(s):  
Jinjie Qian ◽  
Feilong Jiang ◽  
Linjie Zhang ◽  
Kongzhao Su ◽  
Jie Pan ◽  
...  
Keyword(s):  
Pore Structure ◽  
Metal Organic Framework ◽  
Porous Metal ◽  
Sorption Behaviour ◽  
Metal Organic ◽  
Highly Porous ◽  
Organic Framework

A highly porous metal–organic framework structurally consists of three topological kinds of 3-connected 1,3,5-benzenetricarboxylate ligands, Zn2(COO)4, Zn3O(COO)6 and Zn4O(COO)6 SBUs, featuring a new 3,3,3,4,4,6-c hexanodal topology.

Cytotoxicity of a metal–organic framework: Drug delivery

2017 ◽  
Vol 77 ◽  
pp. 68-71 ◽  
Author(s):  
Aiqing Ma ◽  
Zhidong Luo ◽  
Chuying Gu ◽  
Baohong Li ◽  
Jianqiang Liu
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework

High-Throughput Aided Synthesis of the Porous Metal−Organic Framework-Type Aluminum Pyromellitate, MIL-121, with Extra Carboxylic Acid Functionalization

2010 ◽  
Vol 49 (21) ◽  
pp. 9852-9862 ◽  
Author(s):  
Christophe Volkringer ◽  
Thierry Loiseau ◽  
Nathalie Guillou ◽  
Gérard Férey ◽  
Mohamed Haouas ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
High Throughput ◽  
Metal Organic Framework ◽  
Porous Metal ◽  
Metal Organic ◽  
Organic Framework

A Solar Assistant Dehumidifier Based on Porous Metal-Organic Framework

2021 ◽  
Vol 896 ◽  
pp. 13-20
Author(s):  
Xiao Yu Wen
Keyword(s):  
Metal Organic Framework ◽  
Porous Metal ◽  
Modern Architecture ◽  
Activated Alumina ◽  
Additional Energy ◽  
Humidity Control ◽  
Energy Inputs ◽  
Metal Organic ◽  
High Regeneration ◽  
Organic Framework

As an important factor to measure environmental comfort, humidity control is very important. However, previous dehumidification methods have many defects, such as condensation and adsorbents, which often require a lot of energy. The growing requirements of an indoor environment can stem from the development of living levels and technology. Humidity, as an important factor to measure environmental comfort, affects living and production, and indoor humidity control is an indispensable part of modern architecture. However, there are many defects in the previous dehumidification methods, such as condensation dehumidification, which often requires a lot of energy. Traditional adsorbents (such as zeolite silica and activated alumina) have problems with fragile structures or high regeneration temperatures. In this paper, an indoor dehumidification device based on the porous metal-organic framework {MOF-801, Zr6O4(OH)4(Fumarate)6}, can realize the indoor dehumidification process only by using a small amount of solar energy (1 kilowatt per square meter). The device is expected to remove 0.2113 kg/h of moisture per square meter MOF-801, only needs a few additional energy inputs.

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