Encapsulation of 5-Fluorouracil in a Copper(II)-based Porous Metal-organic Framework: Drug Delivery and Inhibiting Human Spinal Cord Tumor Cells

2018 ◽  
Vol 644 (5) ◽  
pp. 317-321 ◽  
Author(s):  
Rongrui Li ◽  
Shichen Liu ◽  
Qingxi Tang ◽  
Tianshu Wang ◽  
Yunchuan Xie ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Spinal Cord ◽  
Tumor Cells ◽  
Metal Organic Framework ◽  
Spinal Cord Tumor ◽  
Porous Metal ◽  
Human Spinal Cord ◽  
Metal Organic ◽  
Organic Framework

Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging

2009 ◽  
Vol 9 (2) ◽  
pp. 172-178 ◽  
Author(s):  
Patricia Horcajada ◽  
Tamim Chalati ◽  
Christian Serre ◽  
Brigitte Gillet ◽  
Catherine Sebrie ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Porous Metal ◽  
Metal Organic ◽  
Organic Framework

Metal Organic Framework [Zn2(1,4-bdc)2(dabco)]n as Drug Delivery System

2013 ◽  
Vol 829 ◽  
pp. 247-250 ◽  
Author(s):  
Negar Motakef-Kazemi ◽  
Seyed Abbas Shojaosadati ◽  
Ali Morsali
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Body Fluid ◽  
Metal Organic Framework ◽  
Porous Metal ◽  
Loading Efficiency ◽  
Metal Organic ◽  
Solvothermal Conditions ◽  
Organic Framework

Porous metal organic framework (MOF) {Zn2(1,4-bdc)2(dabco)}n synthesized under solvothermal conditions. The MOF was used as the carrier matrices for drug delivery system. The ibuprofen as analgesic and anti-inflammatory drug with 0.6 nm molecule size as a model was entrapped into this new carrier with pores distribution of 1.85 nm. The ibuprofen loading efficiency was obtained by thermogravimetric analysis. The ibuprofen loading efficiency of 22% (w/w) was obtained for this MOF. The entrapped ibuprofen was released over several days by soaking the sample in the simulated body fluid (pH 7.4) at 37 °C. The ibuprofen concentrations were analyzed using UV-vis Spectrophotometer at a wavelength of 260 nm. The result of release reveals that this {Zn2(1,4-bdc)2(dabco)}n is suitable as drug delivery system.

β-Cyclodextrin-based Metal-Organic Framework as a Carrier for Zero-order Drug Delivery

2021 ◽  
pp. 129766
Author(s):  
Yanyi Li ◽  
Haobin Huang ◽  
Chongwei Ding ◽  
Xiaoping Zhou ◽  
Hong Li
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Zero Order ◽  
Metal Organic ◽  
Organic Framework

Multifunctionality in an Ion-Exchanged Porous Metal–Organic Framework

2021 ◽  
Vol 143 (3) ◽  
pp. 1365-1376
Author(s):  
Sérgio M. F. Vilela ◽  
Jorge A. R. Navarro ◽  
Paula Barbosa ◽  
Ricardo F. Mendes ◽  
Germán Pérez-Sánchez ◽  
...  
Keyword(s):  
Metal Organic Framework ◽  
Porous Metal ◽  
Metal Organic ◽  
Organic Framework

Unusual pore structure and sorption behaviour in a hexanodal zinc–organic framework material

2014 ◽  
Vol 50 (14) ◽  
pp. 1678-1681 ◽  
Author(s):  
Jinjie Qian ◽  
Feilong Jiang ◽  
Linjie Zhang ◽  
Kongzhao Su ◽  
Jie Pan ◽  
...  
Keyword(s):  
Pore Structure ◽  
Metal Organic Framework ◽  
Porous Metal ◽  
Sorption Behaviour ◽  
Metal Organic ◽  
Highly Porous ◽  
Organic Framework

A highly porous metal–organic framework structurally consists of three topological kinds of 3-connected 1,3,5-benzenetricarboxylate ligands, Zn2(COO)4, Zn3O(COO)6 and Zn4O(COO)6 SBUs, featuring a new 3,3,3,4,4,6-c hexanodal topology.

Cytotoxicity of a metal–organic framework: Drug delivery

2017 ◽  
Vol 77 ◽  
pp. 68-71 ◽  
Author(s):  
Aiqing Ma ◽  
Zhidong Luo ◽  
Chuying Gu ◽  
Baohong Li ◽  
Jianqiang Liu
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework

High-Throughput Aided Synthesis of the Porous Metal−Organic Framework-Type Aluminum Pyromellitate, MIL-121, with Extra Carboxylic Acid Functionalization

2010 ◽  
Vol 49 (21) ◽  
pp. 9852-9862 ◽  
Author(s):  
Christophe Volkringer ◽  
Thierry Loiseau ◽  
Nathalie Guillou ◽  
Gérard Férey ◽  
Mohamed Haouas ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
High Throughput ◽  
Metal Organic Framework ◽  
Porous Metal ◽  
Metal Organic ◽  
Organic Framework
Sign in / Sign up

Export Citation Format

Share Document