scholarly journals Corticotropin test recommended as first-line diagnostic tool

2006 ◽  
Vol 2 (4) ◽  
pp. 185-185
Author(s):  
Katherine Sole
Keyword(s):  
Diagnostic Tool ◽  
First Line ◽  
Corticotropin Test

scholarly journals Ultrasound in Inflammatory and Obstructive Salivary Gland Diseases: Own Experiences and a Review of the Literature

2021 ◽  
Vol 10 (16) ◽  
pp. 3547
Author(s):  
Michael Koch ◽  
Matti Sievert ◽  
Heinrich Iro ◽  
Konstantinos Mantsopoulos ◽  
Mirco Schapher
Keyword(s):  
Salivary Gland ◽  
Diagnostic Tool ◽  
Clinical Symptoms ◽  
Inflammatory Diseases ◽  
Screening Method ◽  
Review Of The Literature ◽  
First Line ◽  
Eligibility Criteria ◽  
Salivary Gland Diseases ◽  
Technical Developments

Background: Ultrasound is established as a diagnostic tool in salivary glands for obstructive diseases such as sialolithiasis and tumors. Concerning inflammatory diseases and in non-sialolithiasis-caused obstruction, much fewer data are available. In recent years, technical development has allowed a better assessment of the gland parenchyma, and knowledge about intraductal pathologies has increased considerably, which has provided new insights and a new interpretation of ultrasound findings. Objectives: To provide a comprehensive review of the literature that includes our own experiences and to point out the state of the art in ultrasound in the diagnostics of inflammatory and obstructive salivary gland diseases, taking adequate techniques and recent technical developments into consideration. Data sources and study eligibility criteria: A systematic literature search was performed in Pubmed using various specific key words. Results: According to the literature results, including our own experiences, ultrasound is of value in up to >90% of cases presenting with inflammatory and/or obstructive diseases. Technical developments (e.g., elastography) and the application of modified ultrasound techniques (e.g., transoral ultrasound) have contributed to these results. Today, ultrasound is considered a first-line diagnostic tool in these diseases. However, in some inflammatory diseases, the final diagnosis can be made only after inclusion of the anamnesis, clinical symptoms, serologic blood tests, or histopathologic investigation. Conclusions: Ultrasound can be considered as a first-line diagnostic tool in obstructive and inflammatory salivary gland diseases. In obstructive diseases, it may be sufficient for diagnostics in >90% of cases. In inflammatory diseases, ultrasound is at least an excellent screening method and can be used to establish the diagnosis in cases of an early suspicion. In all diseases ultrasound can contribute to better management and can be used for monitoring during follow-up.

Three-dimensional endoanal ultrasound should be considered as first-line diagnostic tool in the preoperative work-up for perianal fistulas

2020 ◽  
Vol 125 (7) ◽  
pp. 695-696 ◽  
Author(s):  
Antonio Brillantino ◽  
Francesca Iacobellis ◽  
Alfonso Reginelli ◽  
Adolfo Renzi ◽  
Roberto Grassi
Keyword(s):  
Diagnostic Tool ◽  
Three Dimensional ◽  
Endoanal Ultrasound ◽  
First Line ◽  
Perianal Fistulas ◽  
Preoperative Work Up ◽  
Work Up

scholarly journals Saliva as a first-line diagnostic tool: A spectral challenge for identification of cancer biomarkers

2020 ◽  
Vol 307 ◽  
pp. 112961
Author(s):  
Czesława Paluszkiewicz ◽  
Ewa Pięta ◽  
Monika Woźniak ◽  
Natalia Piergies ◽  
Anna Koniewska ◽  
...  
Keyword(s):  
Diagnostic Tool ◽  
Cancer Biomarkers ◽  
First Line

Whole-Body Multislice Computed Tomography as the First Line Diagnostic Tool in Patients With Multiple Injuries: The Focus on Time

2009 ◽  
Vol 66 (3) ◽  
pp. 658-665 ◽  
Author(s):  
Thomas Erik Wurmb ◽  
Peter Frühwald ◽  
Witiko Hopfner ◽  
Thorsten Keil ◽  
Markus Kredel ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Diagnostic Tool ◽  
Multislice Computed Tomography ◽  
Whole Body ◽  
Multiple Injuries ◽  
First Line

The Role of Core-Needle Biopsy as a First-Line Diagnostic Tool for Initially Detected Thyroid Nodules

Thyroid ◽  
2016 ◽  
Vol 26 (3) ◽  
pp. 395-403 ◽  
Author(s):  
Chong Hyun Suh ◽  
Jung Hwan Baek ◽  
Jeong Hyun Lee ◽  
Young Jun Choi ◽  
Jae Kyun Kim ◽  
...  
Keyword(s):  
Diagnostic Tool ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Thyroid Nodules ◽  
First Line ◽  
Core Needle

scholarly journals Optical Genome Mapping in Routine Human Genetic Diagnostics—Its Advantages and Limitations

Genes ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1958
Author(s):  
Paul Dremsek ◽  
Thomas Schwarz ◽  
Beatrix Weil ◽  
Alina Malashka ◽  
Franco Laccone ◽  
...  
Keyword(s):  
Best Practices ◽  
Diagnostic Tool ◽  
Large Scale ◽  
Genome Mapping ◽  
Genetic Diagnostics ◽  
Structural Variants ◽  
First Line ◽  
Routine Diagnostics ◽  
Human Genomes ◽  
Insight Into

In recent years, optical genome mapping (OGM) has developed into a highly promising method of detecting large-scale structural variants in human genomes. It is capable of detecting structural variants considered difficult to detect by other current methods. Hence, it promises to be feasible as a first-line diagnostic tool, permitting insight into a new realm of previously unknown variants. However, due to its novelty, little experience with OGM is available to infer best practices for its application or to clarify which features cannot be detected. In this study, we used the Saphyr system (Bionano Genomics, San Diego, CA, USA), to explore its capabilities in human genetic diagnostics. To this end, we tested 14 DNA samples to confirm a total of 14 different structural or numerical chromosomal variants originally detected by other means, namely, deletions, duplications, inversions, trisomies, and a translocation. Overall, 12 variants could be confirmed; one deletion and one inversion could not. The prerequisites for detection of similar variants were explored by reviewing the OGM data of 54 samples analyzed in our laboratory. Limitations, some owing to the novelty of the method and some inherent to it, were described. Finally, we tested the successful application of OGM in routine diagnostics and described some of the challenges that merit consideration when utilizing OGM as a diagnostic tool.

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