scholarly journals OC03.01: The capability of breast ultrasound as a first-line diagnostic tool using BIRADS-categories in discriminating benign from malignant lesions

2009 ◽  
Vol 34 (S1) ◽  
pp. 4-5
Author(s):  
H. Hille ◽  
M. Vetter ◽  
B. Hackelöer
Keyword(s):  
Diagnostic Tool ◽  
Breast Ultrasound ◽  
First Line ◽  
Malignant Lesions

Reappraisal of photodynamic therapy as first-line therapy in management of oral pre-malignant lesions

Oral Oncology ◽  
2012 ◽  
Vol 48 (10) ◽  
pp. 915-916 ◽  
Author(s):  
Niharika Swain ◽  
Shwetha V. Kumar ◽  
Sampika Rautray ◽  
Richa
Keyword(s):  
Photodynamic Therapy ◽  
First Line ◽  
First Line Therapy ◽  
Line Therapy ◽  
Malignant Lesions

MO226A NEW DIAGNOSTIC TOOL FOR CKD PATIENTS: CONTRAST-ENHANCED ULTRASONOGRAPHY. A SINGLE CENTER EXPERIENCE

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Mirela Liana Gliga ◽  
Cristian Chirila ◽  
Paula Chirila ◽  
Adriana Gomotarceanu ◽  
Imola Torok ◽  
...  
Keyword(s):  
Diagnostic Tool ◽  
Final Diagnosis ◽  
Medical System ◽  
Focal Lesions ◽  
Non Invasive ◽  
Single Center Experience ◽  
Contrast Enhanced ◽  
Contrast Enhanced Ultrasonography ◽  
Malignant Lesions ◽  
Guidelines And Recommendations

Abstract Background and Aims Contrast-enhanced ultrasonography (CEUS) is a minimally invasive diagnostic tool available for diagnosing microvascular disturbances in tumors and many vascular pathologies. Unlike other radiological contrast agents, it is completely harmless for CKD patients and therefore it is used for the safe diagnosis of many diffuse or focal pathologies. Method We used CEUS examination in 50 CKD patients for the following pathologies: 10 atypical cysts, 15 liver focal lesions, 2 splenic focal lesions, 3 renal infarcts, 12 kidney focal lesions and 8 other organ involvements. Examination was made using a VOLUSON E8 machine (GE Medical System Kreztechnik GmbH Tiefenbach 15, Austria) with a 3.5 MHz convex array abdominal transducer. 2.4 ml of microbubble contrast-agent was administered intravenously and recording of the results were made for 3-5 minutes after injection. Results Depending on the organ vascular characteristics, contrast enhancement and/or wash-out were suggestive for the final diagnosis. In liver lesions there are three phases and in kidneys, spleen, gallbladder, adenopathies there are two vascular phases. We obtained a very good positive predictive value and sensitivity in detecting malignant lesions. Conclusion According to The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound they are used both for hepatic and Non-Hepatic Applications. Being non-invasive and non-irradiating it could be the main diagnostic examination in CKD population in the future.

The Potential of Shear Wave Elastography to Reduce Unnecessary Biopsies in Breast Cancer Diagnosis: An International, Diagnostic, Multicenter Trial

2021 ◽  
Author(s):  
Michael Golatta ◽  
André Pfob ◽  
Christopher Büsch ◽  
Thomas Bruckner ◽  
Zaher Alwafai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Shear Wave ◽  
Cancer Diagnosis ◽  
Shear Wave Elastography ◽  
Breast Cancer Diagnosis ◽  
Multicenter Trial ◽  
Breast Ultrasound ◽  
Histopathologic Evaluation ◽  
International Data ◽  
Malignant Lesions

Abstract Purpose In this prospective, multicenter trial we evaluated whether additional shear wave elastography (SWE) for patients with BI-RADS 3 or 4 lesions on breast ultrasound could further refine the assessment with B-mode breast ultrasound for breast cancer diagnosis. Materials and Methods We analyzed prospective, multicenter, international data from 1288 women with breast lesions rated by conventional 2 D B-mode ultrasound as BI-RADS 3 to 4c and undergoing 2D-SWE. After reclassification with SWE the proportion of undetected malignancies should be < 2 %. All patients underwent histopathologic evaluation (reference standard). Results Histopathologic evaluation showed malignancy in 368 of 1288 lesions (28.6 %). The assessment with B-mode breast ultrasound resulted in 1.39 % (6 of 431) undetected malignancies (malignant lesions in BI-RADS 3) and 53.80 % (495 of 920) unnecessary biopsies (biopsies in benign lesions). Re-classifying BI-RADS 4a patients with a SWE cutoff of 2.55 m/s resulted in 1.98 % (11 of 556) undetected malignancies and a reduction of 24.24 % (375 vs. 495) of unnecessary biopsies. Conclusion A SWE value below 2.55 m/s for BI-RADS 4a lesions could be used to downstage these lesions to follow-up, and therefore reduce the number of unnecessary biopsies by 24.24 %. However, this would come at the expense of some additionally missed cancers compared to B-mode breast ultrasound (rate of undetected malignancies 1.98 %, 11 of 556, versus 1.39 %, 6 of 431) which would, however, still be in line with the ACR BI-RADS 3 definition (< 2 % of undetected malignancies).

Balanitis Xerotica Obliterans

2007 ◽  
Vol 74 (4) ◽  
pp. 206-211
Author(s):  
C. Calcagno
Keyword(s):  
Squamous Cell Carcinoma ◽  
Clinical Presentation ◽  
Local Therapy ◽  
Line Treatment ◽  
First Line ◽  
Balanitis Xerotica Obliterans ◽  
Malignant Lesions ◽  
The Relationship ◽  
First Line Treatment

Balanitis xerotica obliterans (BXO), first described by Stuhmer in 1928, is a chronic, progressive, atrophic, sclerosing process involving prepuce, glans and urethra. Its aetiology is unknown. After a short terminological excursus and a review of the aetiological hypothesis, we have focused on BXO in daily urological practice. We are here describing the clinical presentation and its differential diagnosis with premalignant and malignant lesions of the penis. We tried to define the relationship between BXO and squamous cell carcinoma of the penis. Particular attention was then cast on urethral stenosis. Finally, we focused on the treatment of BXO: corticosteroid local therapy as first line treatment or as adjuvant therapy after circumcision, surgical therapy including circumcision, laser therapy of the glans lesions, meatoplasty in the stenosis of the anterior urethra. We also stressed the need for histological examination of the preputial specimen for a correct follow-up and for medicolegal reasons.

Limitations of Parotid Scans

1977 ◽  
Vol 86 (2) ◽  
pp. 247-250 ◽  
Author(s):  
W. F. McGuirt ◽  
B. F. McCabe
Keyword(s):  
Diagnostic Tool ◽  
Individual Case ◽  
Present Stage ◽  
University Of Iowa ◽  
Stage Of Development ◽  
Malignant Lesions ◽  
Mass Lesions ◽  
The University ◽  
Diagnostic Step ◽  
Nuclear Scanning

In 1967, Gates and Work proposed technetium scanning as a diagnostic tool for salivary neoplasms. Since then, many publications have dealt with the results of scanning. The impression has been that it has certain diagnostic implications, especially in regard to the lesion which is radiopositive on the scan. A review of 29 salivary scans from the University of Iowa Hospitals was carried out, and the conclusion reached was that nuclear scanning using technetium gave little assurance of a specific histological entity in any individual case. Cases having both cold and hot nodules ran the gamut from benign and nonneoplastic to frankly malignant lesions. These cases are illustrated, and the conclusion is reached that salivary scanning at its present stage of development may only delay the proper diagnostic step of excisional (at least lateral lobectomy) biopsy for all nondiffuse parotid mass lesions.

scholarly journals Ultrasound in Inflammatory and Obstructive Salivary Gland Diseases: Own Experiences and a Review of the Literature

2021 ◽  
Vol 10 (16) ◽  
pp. 3547
Author(s):  
Michael Koch ◽  
Matti Sievert ◽  
Heinrich Iro ◽  
Konstantinos Mantsopoulos ◽  
Mirco Schapher
Keyword(s):  
Salivary Gland ◽  
Diagnostic Tool ◽  
Clinical Symptoms ◽  
Inflammatory Diseases ◽  
Screening Method ◽  
Review Of The Literature ◽  
First Line ◽  
Eligibility Criteria ◽  
Salivary Gland Diseases ◽  
Technical Developments

Background: Ultrasound is established as a diagnostic tool in salivary glands for obstructive diseases such as sialolithiasis and tumors. Concerning inflammatory diseases and in non-sialolithiasis-caused obstruction, much fewer data are available. In recent years, technical development has allowed a better assessment of the gland parenchyma, and knowledge about intraductal pathologies has increased considerably, which has provided new insights and a new interpretation of ultrasound findings. Objectives: To provide a comprehensive review of the literature that includes our own experiences and to point out the state of the art in ultrasound in the diagnostics of inflammatory and obstructive salivary gland diseases, taking adequate techniques and recent technical developments into consideration. Data sources and study eligibility criteria: A systematic literature search was performed in Pubmed using various specific key words. Results: According to the literature results, including our own experiences, ultrasound is of value in up to >90% of cases presenting with inflammatory and/or obstructive diseases. Technical developments (e.g., elastography) and the application of modified ultrasound techniques (e.g., transoral ultrasound) have contributed to these results. Today, ultrasound is considered a first-line diagnostic tool in these diseases. However, in some inflammatory diseases, the final diagnosis can be made only after inclusion of the anamnesis, clinical symptoms, serologic blood tests, or histopathologic investigation. Conclusions: Ultrasound can be considered as a first-line diagnostic tool in obstructive and inflammatory salivary gland diseases. In obstructive diseases, it may be sufficient for diagnostics in >90% of cases. In inflammatory diseases, ultrasound is at least an excellent screening method and can be used to establish the diagnosis in cases of an early suspicion. In all diseases ultrasound can contribute to better management and can be used for monitoring during follow-up.

scholarly journals Right occipital transtentorial approach for a pineal malignant germ cell tumor

2021 ◽  
Vol 5 (1) ◽  
pp. V3
Author(s):  
Brian J. A. Gill ◽  
Dominique M. Higgins ◽  
Matei A. Banu ◽  
Michael G. Argenziano ◽  
Neil A. Feldstein ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumors ◽  
Pineal Region ◽  
First Line ◽  
Intracranial Germ Cell Tumors ◽  
Somatic Transformation ◽  
Malignant Germ Cell Tumor ◽  
Occipital Transtentorial Approach ◽  
Malignant Lesions ◽  
Transtentorial Approach

Germ cell tumors account for up to 53% of the malignant lesions found in the pineal region and are typically managed with a combination of radiation therapy and chemotherapy. Malignant somatic transformation of intracranial germ cell tumors is exceedingly rare and has only been reported on two other occasions. Here the authors present the case of a pineal yolk sac tumor that failed optimum first-line treatment and underwent malignant somatic transformation to an enteric mucinous adenocarcinoma requiring surgical intervention. This video demonstrates the technical nuances of the occipital transtentorial approach and the safe microsurgical dissection of lesions within the pineal region. The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID2151.

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