scholarly journals Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Michael E. Kurczy ◽  
Zheng-Jiang Zhu ◽  
Julijana Ivanisevic ◽  
Adam M. Schuyler ◽  
Kush Lalwani ◽  
...  
Keyword(s):  
Fluorinated Nanoparticles

scholarly journals In Vitro Cellular Uptake Studies of Self-Assembled Fluorinated Nanoparticles Labelled with Antibodies

Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1906
Author(s):  
Mona Atabakhshi-Kashi ◽  
Mónica Carril ◽  
Hossein Mahdavi ◽  
Wolfgang J. Parak ◽  
Carolina Carrillo-Carrion ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Cellular Uptake ◽  
Hydrophobic Interactions ◽  
Intrinsic Properties ◽  
Wide Range ◽  
Self Assembled ◽  
Uptake Studies ◽  
Targeting Ability ◽  
Fluorinated Nanoparticles

Nanoparticles (NPs) functionalized with antibodies (Abs) on their surface are used in a wide range of bioapplications. Whereas the attachment of antibodies to single NPs to trigger the internalization in cells via receptor-mediated endocytosis has been widely studied, the conjugation of antibodies to larger NP assemblies has been much less explored. Taking into account that NP assemblies may be advantageous for some specific applications, the possibility of incorporating targeting ligands is quite important. Herein, we performed the effective conjugation of antibodies onto a fluorescent NP assembly, which consisted of fluorinated Quantum Dots (QD) self-assembled through fluorine–fluorine hydrophobic interactions. Cellular uptake studies by confocal microscopy and flow cytometry revealed that the NP assembly underwent the same uptake procedure as individual NPs; that is, the antibodies retained their targeting ability once attached to the nanoassembly, and the NP assembly preserved its intrinsic properties (i.e., fluorescence in the case of QD nanoassembly).

scholarly journals Hydrophobin‐Coated Solid Fluorinated Nanoparticles for 19 F‐MRI

2021 ◽  
pp. 2101677
Author(s):  
Nazeeha Ayaz ◽  
Valentina Dichiarante ◽  
Claudia Pigliacelli ◽  
Jacopo Repossi ◽  
Lara Gazzera ◽  
...  
Keyword(s):  
Fluorinated Nanoparticles

scholarly journals Preparation of Thermo-Responsive and Cross-Linked Fluorinated Nanoparticles via RAFT-Mediated Aqueous Polymerization in Nanoreactors

Molecules ◽  
2017 ◽  
Vol 22 (2) ◽  
pp. 152 ◽  
Author(s):  
Jiachen Ma ◽  
Luqing Zhang ◽  
Bing Geng ◽  
Umair Azhar ◽  
Anhou Xu ◽  
...  
Keyword(s):  
Aqueous Polymerization ◽  
Fluorinated Nanoparticles

scholarly journals Preparation and Investigation of Foaming Amphiphilic Fluorinated Nanoparticles for Enhanced Oil Recovery

Materials ◽  
2017 ◽  
Vol 10 (12) ◽  
pp. 1403 ◽  
Author(s):  
Keliang Wang ◽  
Gang Wang ◽  
Chunjing Lu ◽  
Cuiying Pei ◽  
Ying Wang
Keyword(s):  
Enhanced Oil Recovery ◽  
Oil Recovery ◽  
Fluorinated Nanoparticles

scholarly journals Fluorinated Molecules and Nanotechnology: Future ‘Avengers’ against the Alzheimer’s Disease?

2020 ◽  
Vol 21 (8) ◽  
pp. 2989 ◽  
Author(s):  
Meghna Dabur ◽  
Joana A. Loureiro ◽  
Maria Carmo Pereira
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
New Drugs ◽  
Limiting Factors ◽  
Health Concern ◽  
Aβ Peptide ◽  
Physiochemical Properties ◽  
Unknown Mechanism ◽  
Future Work ◽  
Fluorinated Nanoparticles

Alzheimer’s disease (AD) is a serious health concern, affecting millions of people globally, which leads to cognitive impairment, dementia, and inevitable death. There is still no medically accepted treatment for AD. Developing therapeutic treatments for AD is an overwhelming challenge in the medicinal field, as the exact mechanics underlying its devastating symptoms is still not completely understood. Rather than the unknown mechanism of the disease, one of the limiting factors in developing new drugs for AD is the blood–brain barrier (BBB). A combination of nanotechnology with fluorinated molecules is proposed as a promising therapeutic treatment to meet the desired pharmacokinetic/physiochemical properties for crossing the BBB passage. This paper reviews the research conducted on fluorine-containing compounds and fluorinated nanoparticles (NPs) that have been designed and tested for the inhibition of amyloid-beta (Aβ) peptide aggregation. Additionally, this study summarizes fluorinated molecules and NPs as promising agents and further future work is encouraged to be effective for the treatment of AD.

Controlling Amyloid-β Peptide(1-42) Oligomerization and Toxicity by Fluorinated Nanoparticles

ChemBioChem ◽  
2010 ◽  
Vol 11 (13) ◽  
pp. 1905-1913 ◽  
Author(s):  
Ana M. Saraiva ◽  
Isabel Cardoso ◽  
M. Carmo Pereira ◽  
Manuel A. N. Coelho ◽  
Maria João Saraiva ◽  
...  
Keyword(s):  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Fluorinated Nanoparticles

scholarly journals Cover Picture: Controlling Amyloid-β Peptide(1-42) Oligomerization and Toxicity by Fluorinated Nanoparticles (ChemBioChem 13/2010)

ChemBioChem ◽  
2010 ◽  
Vol 11 (13) ◽  
pp. 1789-1789
Author(s):  
Ana M. Saraiva ◽  
Isabel Cardoso ◽  
M. Carmo Pereira ◽  
Manuel A. N. Coelho ◽  
Maria João Saraiva ◽  
...  
Keyword(s):  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Fluorinated Nanoparticles

scholarly journals Synthesis of fluorinated nanoparticles via RAFT dispersion polymerization-induced self-assembly using fluorinated macro-RAFT agents in supercritical carbon dioxide

RSC Advances ◽  
2017 ◽  
Vol 7 (81) ◽  
pp. 51612-51620 ◽  
Author(s):  
Anhou Xu ◽  
Quanxuan Lu ◽  
Zhiyuan Huo ◽  
Jiachen Ma ◽  
Bing Geng ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Block Copolymer ◽  
Supercritical Carbon Dioxide ◽  
Self Assembly ◽  
Dispersion Polymerization ◽  
Fluorinated Nanoparticles ◽  
Supercritical Carbon

Nano-sized fluorinated block copolymer particles are prepared by RAFT dispersion polymerization with polymerization-induced self-assembly proceeding in supercritical carbon dioxide.

scholarly journals In vivo “hot spot” MR imaging of neural stem cells using fluorinated nanoparticles

2008 ◽  
Vol 60 (6) ◽  
pp. 1506-1511 ◽  
Author(s):  
Jesús Ruiz-Cabello ◽  
Piotr Walczak ◽  
Dorota A. Kedziorek ◽  
Vadappuram P. Chacko ◽  
Anna H. Schmieder ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mr Imaging ◽  
Neural Stem Cells ◽  
Hot Spot ◽  
Fluorinated Nanoparticles
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