scholarly journals Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins

2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Mor Goldfeder ◽  
Margarita Kanteev ◽  
Sivan Isaschar-Ovdat ◽  
Noam Adir ◽  
Ayelet Fishman
Keyword(s):  
Substrate Binding ◽  
Copper Proteins ◽  
Binding Modes ◽  
Type 3

Dicopper complexes of a macrocyclic ligand as models for type 3 copper proteins

1983 ◽  
Vol 105 (17) ◽  
pp. 5693-5695 ◽  
Author(s):  
S. Martin Nelson ◽  
Ferida Esho ◽  
Aidan Lavery ◽  
Michael G. B. Drew
Keyword(s):  
Macrocyclic Ligand ◽  
Copper Proteins ◽  
Type 3 ◽  
Dicopper Complexes

Emission spectra from copper proteins containing type-3 centres

1983 ◽  
Vol 17 (2) ◽  
pp. 125-130 ◽  
Author(s):  
M. Bacci ◽  
M.G. Baldecchi ◽  
P. Fabeni ◽  
R. Linari ◽  
G.P. Pazzi
Keyword(s):  
Emission Spectra ◽  
Copper Proteins ◽  
Type 3

Determination of the drug–DNA binding modes using fluorescence-based assays

2012 ◽  
Vol 422 (2) ◽  
pp. 66-73 ◽  
Author(s):  
Alicia K. Williams ◽  
Sofia Cheliout Dasilva ◽  
Ankit Bhatta ◽  
Baibhav Rawal ◽  
Melinda Liu ◽  
...  
Keyword(s):  
Dna Binding ◽  
Binding Modes

X-ray absorption spectroscopy studies for the determination of adsorption binding modes of selenium oxoanions onto iron and manganese based nanomaterials

2012 ◽  
Vol 1480 ◽  
Author(s):  
Christina M. Gonzalez ◽  
Jason G. Parsons ◽  
Jeffrey Hernandez ◽  
Jorge L. Gardea-Torresdey
Keyword(s):  
Absorption Spectroscopy ◽  
Binding Modes ◽  
Edge Structure ◽  
X Ray ◽  
Microwave Assisted ◽  
Spectroscopy Studies ◽  
X Ray Absorption ◽  
Binding Mechanisms ◽  
Iron And Manganese

ABSTRACTIncreasing concentrations of selenium oxoanions in the environment are placing many animals at risk for reproduction failure and deformities. The understanding of binding mechanisms of selenium oxoanions to iron and manganese based oxide minerals could lead to enhanced understanding of selenium mobility in the environment. In this study, the binding mechanisms of selenium oxoanions, selenite and selenate, to non microwave-assisted and microwave-assisted synthetic Fe3O4, Mn3O4, and MnFe2O4 nanomaterials were investigated through the use of X-ray absorption spectroscopy. The X-ray absorption near-edge structure (XANES) spectroscopy studies revealed the oxidation state of selenite and selenate remains the same after binding occurs to all nanomaterials in pH 2, 4, or 6 environments. The binding modes of selenite and selenate were determined to be bidentate binuclear through use of Extended x-ray absorption fine structure (EXAFS) and were independent of nanomaterials, synthetic technique, and pH.

Monooxygenase Activity of Type 3 Copper Proteins

2007 ◽  
Vol 40 (7) ◽  
pp. 592-600 ◽  
Author(s):  
Shinobu Itoh ◽  
Shunichi Fukuzumi
Keyword(s):  
Copper Proteins ◽  
Monooxygenase Activity ◽  
Type 3

scholarly journals Spinocerebellar ataxia type 3: subphenotypes in a cohort of brazilian patients

2014 ◽  
Vol 72 (9) ◽  
pp. 659-662 ◽  
Author(s):  
Adriana Moro ◽  
Renato P. Munhoz ◽  
Walter O. Arruda ◽  
Salmo Raskin ◽  
Mariana Moscovich ◽  
...  
Keyword(s):  
Spinocerebellar Ataxia ◽  
Spinocerebellar Ataxia Type ◽  
Cerebellar Syndrome ◽  
Motor Systems ◽  
Spinocerebellar Ataxia Type 3 ◽  
Future Studies ◽  
Type 3 ◽  
Extrapyramidal Motor ◽  
Genotype Correlation

Spinocerebellar ataxia type 3 (SCA3) involves cerebellar, pyramidal, extrapyramidal, motor neuron and oculomotor systems with strong phenotypic heterogeneity, that lead us to classify the disorder into different clinical subtypes according to the predominantly affected motor systems. Method The series comprises 167 SCA3 patients belonging to 68 pedigrees, studied from 1989-2013. These patients were categorized into seven different subphenotypes. Results SCA3 cases were clustered according to the predominant clinical features. Three most common forms were subphenotype 2, characterized by ataxia and pyramidal symptom was observed in 67.5%, subphenotype 3 with ataxia and peripheral signs in 13.3%, and subphenotype 6 with pure cerebellar syndrome in 7.2%. Conclusion Our study was the first to systematically classify SCA3 into seven subphenotypes. This classification may be particularly useful for determination of a more specific and direct phenotype/genotype correlation in future studies.

Monooxygenase Activity of Type 3 Copper Proteins

ChemInform ◽  
2007 ◽  
Vol 38 (41) ◽  
Author(s):  
Shinobu Itoh ◽  
Shunichi Fukuzumi
Keyword(s):  
Copper Proteins ◽  
Monooxygenase Activity ◽  
Type 3

Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3

2017 ◽  
Vol 57 (2) ◽  
pp. 560-563 ◽  
Author(s):  
Chin Piow Wong ◽  
Takayoshi Awakawa ◽  
Yu Nakashima ◽  
Takahiro Mori ◽  
Qin Zhu ◽  
...  
Keyword(s):  
Substrate Binding ◽  
Binding Modes
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